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200 Possible Causes for Broad Nasal Bridge, Macroglossia

  • Down Syndrome

    bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21 — called also trisomy 21 First Known Use of Down syndrome[merriam-webster.com] Dental malocclusion and macroglossia are associated. Technical modifications to increase macroglossia surgery safety and efficacy have been described.[doi.org] bridge, protruding tongue, high-arched palate, dental abnormalities, and a short and broad neck.[symptoma.com]

  • Mucopolysaccharidosis 6

    [rarediseases.org] Jaw & Teeth Macroglossia . , , , , , Source MeSH Alveolar Process Child Consanguinity Dentigerous Cyst Gingival Hyperplasia Humans Macroglossia Male Mouth[symptoma.com] . , , , , , Source MeSH Alveolar Process Child Consanguinity Dentigerous Cyst Gingival Hyperplasia Humans Macroglossia Male Mouth Abnormalities Mucopolysaccharidosis VI Open[unboundmedicine.com] The features of MPS VI include macrocephaly, hydrocephalus and macroglossia.[ivami.com]

  • Mucopolysaccharidosis 2

    Common signs and symptoms include a large head, full lips, large rounded cheeks, a broad nose, hoarse voice and an enlarged tongue (macroglossia).[symptoma.com] Physical findings: • Coarse facial features; • Narrowing of the cervical spinal canal (spinal stenosis); • Enlarged tongue (macroglossia) and vocal cords; • Enlarged liver[secure.ssa.gov] Between ages 2 and 4, they develop full lips, large rounded cheeks , a broad nose , and an enlarged tongue ( macroglossia ).[ghr.nlm.nih.gov]

  • Mucopolysaccharidosis 1

    Developmental delays, hearing loss and macroglossia contribute to severely reduced language acquisition.[symptoma.com] […] hydrocephalus), heart valve abnormalities, distinctive-looking facial features that are described as "coarse," an enlarged liver and spleen (hepatosplenomegaly), and a large tongue (macroglossia[ghr.nlm.nih.gov] This type of deposit can as well be seen on the pharynx walls and, when in association with macroglossia and mandible abnormalities (occasionally they are seen on MPS cases[arquivosdeorl.org.br]

  • Mucopolysaccharidosis

    However, access to secure the airway and for conventional surgery can be challenging, due to limited neck extension, macroglossia and reduced mouth opening.[ncbi.nlm.nih.gov] […] hydrocephalus), heart valve abnormalities, distinctive-looking facial features that are described as "coarse," an enlarged liver and spleen (hepatosplenomegaly), and a large tongue (macroglossia[ghr.nlm.nih.gov] Beyond neurological, orthopedic, and ophthalmological findings, macroglossia, tonsillar hypertrophy, otitis media and conductive hearing loss, upper airway obstruction, valvular[symptoma.com]

  • Simpson Dysmorphia Syndrome

    Characteristic dysmorphic features include macrocephaly with coarse, distinctive facies with a large protruding jaw, broad nasal bridge and cleft palate.[uniprot.org] Keywords: Simpson-Golabi-Behmel Syndrome, Anesthetic Management, Macroglossia 1.[file.scirp.org] An X-linked dysmorphia complex [MIM 312870] which is characterised by a large, square protruding jaw, a broad nasal bridge, an upturned nose tip, and macroglossia, resulting[medical-dictionary.thefreedictionary.com]

  • Hypertrichotic Osteochondrodysplasia

    Clinical description Dysmorphic features include macrocephaly and a coarse facial appearance with thick eyebrows, prominent supraorbital ridges, broad nasal bridge, anteverted[orpha.net] Some features are suggestive of a storage disorder, including macrocephaly and coarse facial features, with a broad nasal bridge, epicanthal folds, wide mouth, and full lips[diseaseinfosearch.org] […] acromegaloid facial features (HAFF) are characterized by congenital hypertrichosis; distinctive coarse facial features (including broad nasal bridge, wide mouth with full lips and macroglossia[ncbi.nlm.nih.gov]

  • Pallister-Killian Syndrome

    nasal bridge, short nose with upturned nares, large mouth with downturned corners and prominent upper lip.[orpha.net] The disorder in older children and young adults is characterized by a coarse and flat facies, macroglossia prognathia, everted lower lip, and severe psychomotor retardation[ncbi.nlm.nih.gov] Oro-dental features, such as "Pallister lip," macroglossia, delayed eruption of primary teeth, high arched-palate, prognathism, and cleft palate have been occasionally reported[ncbi.nlm.nih.gov]

  • Smith-Magenis Syndrome

    The common clinical findings were: speech delay with behavioural problems associated with broad flat midface, brachycephaly, broad nasal bridge and brachydactyly.[ncbi.nlm.nih.gov] Other findings including protrusion of the mandibular anterior teeth, increased bony chin size, and macroglossia were noted, which may contribute to the prognathic appearance[ncbi.nlm.nih.gov] The main clinical features consist of a broad flat midface with brachycefaly, broad nasal bridge, brachydactily, speech delay, hoarse deep voice and peripheral neuropathy.[ncbi.nlm.nih.gov]

  • Beckwith-Wiedemann Syndrome

    , flat nasal bridge, and micrognathia.[ncbi.nlm.nih.gov] Its most common feature is macroglossia, being present in most cases. Clinically macroglossia can compromise the airway, cause dysphagia, drooling and poor cosmesis.[ncbi.nlm.nih.gov] Beckwith Wiedemann syndrome (BWS) is a rare, congenital overgrowth disorder that is characterized by macroglossia, anterior abdominal wall defects, visceromegaly, gigantism[ncbi.nlm.nih.gov]

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