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66 Possible Causes for Brushfield Spot, Drooling

  • Down Syndrome

    Brushfield's spots: Speckled iris. Little white spots that slightly elevated on the surface of the iris arranged in a ring concentric with the pupil.[medterms.com] Results: Ocular findings included nystagmus (29.2%), esotropia (26.1%), epiphora (21.5%), Brushfield spots (16.9%), lens opacities (12.3%), abnormalities of the retinal vessels[dx.doi.org] These spots occur in normal children but are far more frequent in Down's syndrome (trisomy 21).[medterms.com]

  • Peritonsillar Abscess

    […] on the colored part of the eye (Brushfield spots) Physical development is often slower than normal.[mclarenhealthplan.org] Children younger than 5 years who present with poor oral intake, high fever, drooling, and trismus should be suspected of having a peritonsillar abscess.[ncbi.nlm.nih.gov] Patients who received initial surgical management had larger abscess size (2.6 vs. 1.3 cm, P .001) and were and more likely to have muffled voice (79% vs. 47%, P .001), drooling[ncbi.nlm.nih.gov]

  • Receptive Aphasia

    spots, epicanthic folds, brachycephaly, simian creases Down syndrome Goiter Pendred syndrome Café au lait spots Neurofibromatosis Adenoma sebaceum, shagreen patches, hypopigmented[aafp.org] Excessive drooling can sometimes accompany language delay. Other children may have poor coordination, such as difficulty catching a ball or riding a bicycle.[childneurologyfoundation.org] […] retardation, cerebral palsy, hearing loss Deformities of auricle or external ear canal Hearing loss Enlarged pinna, macroorchidism Fragile X syndrome Upward slanting eyes, Brushfield[aafp.org]

  • Degenerative Brain Disorder

    spots, pigmentary retinopathy, and nerve dysplasia). • More than 90% show postnatal growth failure 26.[slideshare.net] Drooling, unintentional weight loss and swelling of the feet, ankles or legs are other symptoms affecting amyotrophic lateral sclerosis sufferers.[livestrong.com] […] reaction time, voice changes or decreased facial expression; gradual loss of automatic movement, often leading to decreased blinking, decreased frequency of swallowing, and drooling[aans.org]

  • Infantile Choroidocerebral Calcification Syndrome

    Eye problems associated with this syndrome are myopia and "Brushfield" spots (gray or pale yellow spots at the periphery of the iris).[tsbvi.edu] […] behavior High-frequency hearing impairment Abnormality of the basal ganglia Anemia Babinski sign Polymicrogyria Hemolytic anemia Spontaneous abortion Mitral valve prolapse Drooling[mendelian.co]

  • Familial Developmental Dysphasia

    spots, epicanthic folds, brachycephaly, simian creases Down syndrome Goiter Pendred syndrome Café au lait spots Neurofibromatosis Adenoma sebaceum, shagreen patches, hypopigmented[aafp.org] Excessive drooling can sometimes accompany language delay. Other children may have poor coordination, such as difficulty catching a ball or riding a bicycle.[childneurologyfoundation.org] […] progresses: Swallowing difficulties (usually a later symptom): At least 50% of people with Parkinson’s develop swallowing problems (dysphagia) that may cause the person to drool[caregiver.org]

  • Familial Congenital Nasolacrimal Duct Obstruction

    Associated features include generalized hypotonia, transverse palmar creases (simian lines),shortening and incurving of the 5th fingers (clinodactyly),Brushfield's spots and[quizlet.com] […] is shorter and has an upward curve Eustachian tube is relatively wider, shorter and more horizontal Reflux of nasopharyngeal secretions Salivation increases by 3 months Drools[quizlet.com] Common minor anomalies include: upward-slanting eyes inner epicanthal folds small upturned nose with saddle bridge a protruding tongue that develops fissures with age Brushfield[medicalhomeportal.org]

  • Smith-Magenis Syndrome

    Both conditions share brachycephaly, upward slanting palpebral fissures, a short and broad nose, a round face with midface flattening, iris hamartomas (Brushfield spots in[jmg.bmj.com] (low muscle tone) * Short stature * Small, short and wide hands and feet * Scoliosis * Hearing loss * Flat feet * Over responsive reflexes * Open mouth posture, frequent drooling[ctmq.org] […] dysfunction, in which affected individuals have difficulties controlling the lips, tongue and jaw muscles, may also develop and can cause tongue protrusion and frequent drooling[rarediseases.org]

  • Gradenigo's Syndrome

    J Pediatr. 2009;123:124–133 Angela Dillon, MA Brushfield Spots Brushfield's spots: Speckled iris.[michiganorthopticprogram.com] 食道二重造影法 esophagography 同 diplopia double vision 複視 " downbeat nystagmus 下眼瞼向き眼振 同2 Down syndrome ダウン症候群 " 1trisomy 同 iron lung Drinker respirator ドリンカー呼吸器 " 同 sialorrhea drooling[upslide.site] : No, statistics show that patients with brown irides are never seen to have Brushfield spots.[michiganorthopticprogram.com]

  • Alpers Syndrome

    spots, upslanting palpebral fissures, epicanthal folds Most cases not inherited Trisomy 21 (most cases), translocation, mosaic #190685 DOYNE HONEYCOMB DYSTROPHY (MALATTIA[eyewiki.aao.org] As she's more awake I spend a lot less time wiping the drool from her lips.[livingwithalpersaveriestory.blogspot.com] REFERENCE DELLEMAN SYNDROME (OCULOCEREBROCUTANEOUS SYNDROME) Anophthalmia, microphthalmia, eyelid coloboma, orbital cysts, nystagmus Isolated cases - 164180 DOWN SYNDROME Iris brushfield[eyewiki.aao.org]

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