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226 Possible Causes for Brushfield Spots

  • Down Syndrome

    Individuals with DS may have certain physical attributes including: Almond-shaped eyes with striking Brushfield spots (small, white, crescent-shaped markings) on the irises[babycenter.com] […] on the colored part (iris) of the eye called Brushfield's spots Short height Infants with Down syndrome may be average size, but typically they grow slowly and remain shorter[mayoclinic.org] […] on the colored part of the eye (Brushfield spots) Physical development is often slower than normal.[mountsinai.org]

  • Zellweger Syndrome

    We did not observe any Brushfield spots, any renal and brain cysts, or adrenal insufficiency.[ncbi.nlm.nih.gov] Clinical Features [ edit ] Craniofacial Features Flat occiput and face Anteverted nares Epicanthal folds Brushfield spots High forehead Large fontanels Shallow orbits Ocular[en.wikibooks.org] Ophthalmologic Manifestations corneal clouding Brushfield spots cataracts glaucoma optic nerve dysplasia pigmentary retinopathy 4.[pedbase.org]

  • Brachyphalangy Polydactyly and Tibial Aplasia/Hypoplasia

    spots Fraser’s syndrome (219000) Cryptophthalmos, malformed lacrimal ducts, hypertelorism, blindness Glucose transport defect (606777) Abnormal paroxysmal eye movements;[clinicalgate.com] […] palpebral fissures, chorioretinal dystrophy, myopia, decreased visual acuity, optic atrophy Down syndrome (190685) Upslanting palpebral fissures, epicanthal folds, iris Brushfield[clinicalgate.com]

  • Autosomal Dominant Mental Retardation 5

    ) spots overlying the iris of the eye.[diapedia.org] Will see epicanthal folds, simian crease , brushfield spots in eyes.[kumc.edu] […] short stature, a small rounded head flattened posteriorly, broadening of the neck, slanting eyes, a flattened nose, small broad hands with a single palmar crease and white (Brushfield[diapedia.org]

  • Ringed Hair Disease

    spots genetic disorders / phakomatosis / neurofibromatosis / genetic disorders/ phakomatosis/ neurofibromatosis genetic disorders / phakomatosis / neurofibromatosis / genetic[dermquest.com]

  • Congenital Cataract-Hearing Loss-Severe Developmental Delay Syndrome

    Eye problems associated with this syndrome are myopia and "Brushfield" spots (gray or pale yellow spots at the periphery of the iris).[tsbvi.edu] spots, epicanthic folds, brachycephaly, simian creases Down syndrome Goiter Pendred syndrome Café au lait spots Neurofibromatosis Adenoma sebaceum, shagreen patches, hypopigmented[aafp.org] spots), 3 fontanelles with delayed closure, midface hypoplasia, mild microcephaly, short hard palate, small nose with flat nasal bridge, protruding tongue MSK - short metacarpals[quizlet.com]

  • High Myopia-Sensorineural Deafness Syndrome

    Eye problems associated with this syndrome are myopia and "Brushfield" spots (gray or pale yellow spots at the periphery of the iris).[tsbvi.edu] Ocular features include Brushfield's spots (small white spots on the periphery of the iris which are found sometimes in unaffected children).[patient.info]

  • Hypertelorism and Tetralogy of Fallot

    Down21 - non-disjunction causing trisomy 21; or Robertsonian translocation (14;21)Epicanthic folds; flat nasal bridge; protruding tongue; Brushfield spots; increased space[dontforgetthebubbles.com]

  • Congenital Nystagmus 2, Autosomal Dominant

    Eye problems associated with this syndrome are myopia and "Brushfield" spots (gray or pale yellow spots at the periphery of the iris).[tsbvi.edu]

  • Iris Disorder

    Lopp, OD Brushfield spots Brushfield spots are a type of iris feature that is found in 90% of patients having Down syndrome.[milesresearch.com] These are somewhat distinct from Brushfield spots. Example of Wolfflin Spots: Image from Photo Library of M. H.[milesresearch.com] ) Horner-Trantas Dots Abnormal Microvascular Topography Arteriolar Narrowing Signs in Iris Images Lisch Nodules Wolfflin Spots Brushfield Spots Bilateral Heterochromia Gray[milesresearch.com]

Further symptoms