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265 Possible Causes for Brushfield Spots, Duplication or Triplication of Phalanges, Wide Space Between the First and Second Toe

  • Down Syndrome

    A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] Brushfield's spots: Speckled iris. Little white spots that slightly elevated on the surface of the iris arranged in a ring concentric with the pupil.[medterms.com] spacing, often with a deep plantar groove between the first and second toes.[dx.doi.org]

    Missing: Duplication or Triplication of Phalanges
  • Kleiner Holmes Syndrome

    […] gap between first and second toes Wide space between 1st, 2nd toes Wide space between first and second toes Widely spaced 1st-2nd toes Widely spaced first and second toes[rarediseases.info.nih.gov] Radiographs show broad, shortened, misshapen first metatarsals and may associate incomplete or complete duplication of proximal phalanges and duplication or triplication of[malacards.org] […] gap between first and second toes Wide space between 1st, 2nd toes Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first[rarediseases.info.nih.gov]

    Missing: Brushfield Spots
  • Familial Congenital Nasolacrimal Duct Obstruction

    space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org] Associated features include generalized hypotonia, transverse palmar creases (simian lines),shortening and incurving of the 5th fingers (clinodactyly),Brushfield's spots and[quizlet.com] […] protruding tongue that develops fissures with age Brushfield spots small ears short neck with redundant skin folds brachycephaly flat occiput single palmar (simian) crease wide[medicalhomeportal.org]

    Missing: Duplication or Triplication of Phalanges
  • Adactyly of Foot

    Synonyms:Anterior Polydactyly Replaces: Anterior Duplication of the Limb, Tibial Polydactyly Foot, Preaxial Polydactyly of Subjective: A widely spaced gap between the first[quizlet.com] spots, 89 hamartomata, 24 isolated congenital nail dysplasia, 469 J Jackson-Weiss syndrome, 209 Jadassohn nevus phakomatosis, 366 joint ankylosis, 59 contracture, 59 hypermobility[docplayer.net] toe (the great toe) and the second toe Comments:The term is a subjective one but should be used when the gap between the toes is as wide as the second toe is broad.[quizlet.com]

    Missing: Duplication or Triplication of Phalanges
  • Dubowitz Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov] […] infection infections, recurrent Predisposition to infections Susceptibility to infection [ more ] 0002719 Respiratory insufficiency Respiratory impairment 0002093 Sandal gap Gap between[rarediseases.info.nih.gov]

    Missing: Brushfield Spots Duplication or Triplication of Phalanges
  • Zellweger Syndrome

    We did not observe any Brushfield spots, any renal and brain cysts, or adrenal insufficiency.[ncbi.nlm.nih.gov] Clinical Features [ edit ] Craniofacial Features Flat occiput and face Anteverted nares Epicanthal folds Brushfield spots High forehead Large fontanels Shallow orbits Ocular[en.wikibooks.org] Eye abnormalities and vision problems like brushfield spots, abnormal retinal pigmentation, optic disk pallor, glaucoma and cataract occur as well.[ic.steadyhealth.com]

    Missing: Duplication or Triplication of Phalanges Wide Space Between the First and Second Toe
  • Ring Chromosome 10

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov] […] weak muscle tone 0001252 Pectus excavatum Funnel chest 0000767 Renal hypoplasia/aplasia Absent/small kidney Absent/underdeveloped kidney [ more ] 0008678 Sandal gap Gap between[rarediseases.info.nih.gov]

    Missing: Brushfield Spots Duplication or Triplication of Phalanges
  • Atelosteogenesis Type 2

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov] Flattened vertebrae 0000926 Pulmonary hypoplasia Small lung Underdeveloped lung [ more ] 0002089 Respiratory insufficiency Respiratory impairment 0002093 Sandal gap Gap between[rarediseases.info.nih.gov]

    Missing: Brushfield Spots Duplication or Triplication of Phalanges
  • Other Specified Congenital Malformations of the Eye

    Clinically indistinguishable from Brushfield spots of Down syndrome Name the condition: Acid accumulation in cartilage & tendons Associations: arthropathy, dark urine Ocular[quizlet.com] spots, upslanting palpebral fissures, epicanthal folds Most cases not inherited Trisomy 21 (most cases), translocation, mosaic #190685 DOYNE HONEYCOMB DYSTROPHY (MALATTIA[eyewiki.aao.org] spots, upslanting palpebral fissures, epicanthal folds/Most cases not inherited /Trisomy 21 (most cases), translocation, mosaic /#190685 DOYNE HONEYCOMB DYSTROPHY (MALATTIA[eyewiki.org]

    Missing: Duplication or Triplication of Phalanges Wide Space Between the First and Second Toe
  • High Myopia-Sensorineural Deafness Syndrome

    Eye problems associated with this syndrome are myopia and "Brushfield" spots (gray or pale yellow spots at the periphery of the iris).[tsbvi.edu] Ocular features include Brushfield's spots (small white spots on the periphery of the iris which are found sometimes in unaffected children).[patient.info]

    Missing: Duplication or Triplication of Phalanges Wide Space Between the First and Second Toe

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