Buffalo-hump: Causes & Reasons

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Possible Causes for buffalo hump

Obesity

Cushing syndrome typically causes fat to accumulate in the face, making it look full (called moon face), and behind the neck (called a buffalo hump). [msdmanuals.com]

Morbid Obesity

Morbid obesity is associated with liver pathology, most commonly non-alcoholic steatohepatitis (NASH) leading to cirrhosis. However, the morbid obesity impedes qualification for organ transplantation. We present a case report of a 56-year-old woman who underwent bariatric procedure followed by liver transplantation[…] [ncbi.nlm.nih.gov]

Paraneoplastic Syndrome

hump generally do not manifest, as hypercortisolism is an acute phenomenon and patients do not live long enough for the manifestation of morphological changes [33, 34]. [intechopen.com]

Characteristic findings on physical examination include abnormal fat deposition (moon facies, buffalo hump, centripetal obesity) and violaceous striae (20). [atm.amegroups.com]

[…] patients generally are found to have electrolyte imbalances rather than having a cushingoid appearance, although typical cushingoid characteristics such as moon face and buffalo [intechopen.com]

Cushing Syndrome

hump"), increased supraclavicular fat pads, and white abdominal striae. [ncbi.nlm.nih.gov]

On examination, the child had central obesity, moon facies, and buffalo hump. [ncbi.nlm.nih.gov]

hump Have weak muscles or bones, including osteoporosis, bone pain, and fractures Show skin changes, including: Acne or skin infections Reddish-purple stretch marks called [web.archive.org]

Pituitary Cushing Syndrome

In addition to the typical clinical symptoms such as moon face,buffalo hump,and central obesity,the CD patients may also experience mental disorders and cognitive dysfunction [ncbi.nlm.nih.gov]

She did not have a Cushingoid appearance, such as a moon-face, buffalo hump, purple striae or central obesity. [ncbi.nlm.nih.gov]

[Photographer: Renea's family] September 2001 Libby's 3rd birthday party.....full-blown Cushing's....moon face, acne, buffalo hump, facial flushing, sweating all the time. [cushings-help.com]

Iatrogenic Cushing Syndrome

View of buffalo hump, on the patient’s neck. F ig. 2. View of buffalo hump, on the patient’s neck. [academic.oup.com]

The authors note that the patient was referred to the pediatric department with stunted growth, truncal obesity, purple skin striate, buffalo hump, and moon face six months [medicalxpress.com]

He had a moon face appearance with truncal obesity, buffalo hump, hypertrichosis in trunk, and purple striae in the axilla, periumbilical, and inguinal region. [ncbi.nlm.nih.gov]

Adrenocortical Carcinoma

Symptoms of increased cortisol or other adrenal gland hormones may include: Fatty, rounded hump high on the back just below the neck (buffalo hump) Flushed, rounded face with [medlineplus.gov]

Symptoms of increased cortisol or other adrenal gland hormones may include: Fatty, rounded hump high on the back just below the neck ( buffalo hump ) Flushed, rounded face [nlm.nih.gov]

Symptoms Symptoms of increased cortisol or other adrenal gland hormones may include: Fatty, rounded hump high on the back just below the neck ( buffalo hump ) Flushed, rounded [ufhealth.org]

Adrenal Cushing Syndrome

It causes characteristic symptoms including obesity of the trunk and thinning of the extremities, a thickening at the base of neck called a buffalo hump, a rounding of the [surgery.med.miami.edu]

The clinical suspicion of Cushing's arises from clinical signs such as thin skin, bruising, hypertension, 'buffalo hump', plethora, moon face, purple striae, and proximal [endocrinesurgeon.co.uk]

Symptoms: Moon face (round, red, and full) Weight gain Buffalo hump (a collection of fat between the shoulders) Central obesity with protruding abdomen and thin extremities [uclahealth.org]

Lipodystrophy

Liposuction is often explored for the removal of accumulated fat around the back of the neck (commonly referred to as a "buffalo hump"). [aids.about.com]

These include, but are not limited to, having sunken cheeks and/or "humps" on the back or back of the neck (also referred to as buffalo hump) which also exhibits due to excess [en.wikipedia.org]

Fat deposits behind the neck (buffalo humps) can get big enough to cause headaches and problems with breathing and sleeping. [aidsinfonet.org]

ACTH-Dependent Cushing Syndrome

It causes characteristic symptoms including obesity of the trunk and thinning of the extremities, a thickening at the base of neck called a buffalo hump, a rounding of the [surgery.med.miami.edu]

[…] thin skin, poor wound healing, hirsutism or scalp thinning; pigmentation (usually sign of ACTH dependent Cushings) Weight gain/central obesity (97%); dorsocervical fat pad (buffalo [dundeemedstudentnotes.wordpress.com]

[…] features 6 : rounded face, sometimes described as 'moon-shaped' progressive centripetal obesity and weight gain prominent supraclavicular fat pad, sometimes known as a 'buffalo [radiopaedia.org]

ACTH-Independent Cushing Syndrome

hump or dorsocervical fat pad Enlarged fat pads in the supraclavicular fossa Truncal obesity Generalized obesity Facial plethora Wasting in the extremities Acne Easy bruising [specialty.mims.com]

(1) Rapid weight gain/inability to lose weight (2) Moon facies (3) Dorsocervical fat pad (Buffalo hump) (4) Hirsutism and irregular menses in women (5) Glucose intolerance [quizlet.com]

Corticotroph Pituitary Adenoma

[…] signs of Cushings syndrome and disease may include: Change in body habitus: weight gain in face (moon face), above the collar bone (supraclavicular) and on back of neck (buffalo [pituitary.org]

Weight gain (with centripetal distribution, buffalo-hump, supraclavicular fat pad), arterial hypertension, ecchymoses and purple striae on flanks and lower abdomen are all [primarycare.imedpub.com]

Adrenal Gland Neoplasm

Most patients present with features of glucocorticoid excess (Cushing's syndrome), which includes central obesity, peripheral weakness, abdominal striae, buffalo hump, hirsutism [surgwiki.com]

[…] or buffalo hump) Purple stretch marks on the abdomen Excessive hair growth on the face, chest, and back in women Menstrual irregularities Weakness and loss of muscle mass [cancer.org]

hump,” and fat pads on the face, creating what’s known as a “moon face.” [nyulangone.org]

Ectopic ACTH Syndrome

She did not have other findings such as striae, supraclavicular fat accumulation, and buffalo hump. [ncbi.nlm.nih.gov]

Classic features of Cushing's syndrome are: moon face (round, red, and full) "buffalo hump" -- collection of fat between the shoulders central obesity -- protruding abdomen [uclahealth.org]

Cushing Syndrome due to Macronodular Adrenal Hyperplasia

[…] nodular adrenal hyperplasia; “ Decrease ACTH” due to negative feedback Signs and Symptoms of Cushing’s syndrome: Hypertension, Weight gain, Moon facies, Truncal obesity, Buffalo [medical-institution.com]

Classical Cushing Syndrome  Many of the classic symptoms of hypercortisolism, such as central obesity, moon faces, buffalo hump, proximal muscle weakness, easy bruisability [slideshare.net]

Nelson Syndrome

hump" a red, puffy, rounded face Other symptoms include: skin that bruises easily large purple stretch marks weakness in your upper arms and thighs a low libido and fertility [nhs.uk]

hump' purple skin striae easy skin bruising acanthosis nigricans proximal myopathy depression and other mood disorders osteoporosis hypertension hyperglycemia and development [radiopaedia.org]

Hypertension

On physical examination, centripetal obesity with 'moon face' and 'buffalo's hump' were identified, and wheezing on left lung was heard. [ncbi.nlm.nih.gov]

Signs suggesting a secondary medical cause of chronic hypertension Centripetal obesity, "buffalo hump," and/or wide purple abdominal striae suggest glucocorticoid excess. [web.archive.org]

Signs suggesting a secondary medical cause of chronic hypertension Centripetal obesity, "buffalo hump," and/or wide purple abdominal striae suggest glucocorticoid excess; [emedicine.medscape.com]

Multiple Symmetric Lipomatosis

Fat deposition in the parotid region (hamster cheeks), cervical region (horse collar), posterior neck (buffalo hump) and upper trunk gives the patient a "pseudoathletic appearance [doi.org]

Typical locations include the cervical region ("horse collar"); posterior neck ("buffalo hump"); parotids: submentovertex and retroauricular ("hamster cheek"); and on the [rbcp.org.br]

Urso, R, Gentil, M 2001 Are “buffalo hump” syndrome, Madelung’s disease, and multiple symmetrical lipmatosis variants of the same dysmetabolism? [doi.org]

Endocrine Dysfunction

Key features are central fat deposition resulting in a moon face, fat deposition over the clavicles and upper spine ("buffalo hump") and around the abdomen with production [diapedia.org]

hump -increased facial hair in women Etiologies of Addisons disease -autoimmune -secondary insufficiency due to pituitary or hypothalamic disorder -withdrawal of steroid [quizlet.com]

Symptoms of Cushing’s syndrome include: Buffalo hump (fat between the shoulder blades) Skin discoloration such as bruising Fatigue Feeling very thirsty Thinning and weakening [secondopiniongroup.com]

Benign Lipomatous Neoplasm

[…] as buffalo hump. [wikinow.co]

Keywords Subcutaneous Nodule Buffalo Hump Motor Nerve Branch Suction Cannula Suction Lipectomy These keywords were added by machine and not by the authors. [link.springer.com]

A 51-year-old man with HIV and cervicodorsal lipodystrophy (buffalo hump). JAMA. 2013;309:1289–1290. 45. Apfelberg DB. [dovepress.com]

Cushing Ulcer

MOODIAH M- moon face,buffalo hump O- osteoporosis O- obesity and oedema from Na & H2O retension D- diabetes I- infections A- atherosclerosis H- hypertension, hirsutism A Cushing [notesmedical.blogspot.com]

Acanthosis Nigricans

It is better marker of insulin resistance than the traditionally used markers like BMI, or buffalo hump. [ijem.in]

She had macrocephaly with a prominent nose, round face and a “buffalo hump”. There were no skin tags or oral and tongue changes. [karger.com]

Metabolic Syndrome

He had marked loss of sc fat from the face and limbs but had increased sc fat deposition in the neck region anteriorly and posteriorly showing buffalo hump. [ncbi.nlm.nih.gov]

Excess fat accumulation in the dorso-cervical (causing a buffalo-hump), supraclavicular and submental regions gives these patients a “Cushingoid appearance” and many of these [ncbi.nlm.nih.gov]

Sinusitis

Metabolic: Corticosteroids cause a movement of body fat to the face and torso, resulting in "moon face", "buffalo hump", and "pot belly" or "beer belly", and cause movement [en.wikipedia.org]

Lipedema

In men with lipodystrophy, SAT can be increased on the abdomen and chest (gynecomastia), and a dorsocervical fat pad or “buffalo hump” is common 9, 10. [doi.org]

Are 'buffalo hump' syndrome, Madelung's disease and multiple symmetrical lipomatosis variants of the same dysmetabolism? Aids 2001; 15 : 290–1. 54. [doi.org]

“Buffalo hump” in men with HIV-1 infection. Lancet 1998; 351 : 867–70. 11. Grunfeld C, Rimland D, Gibert CL, Powderly WG, Sidney S, Shlipak MG, et al. [doi.org]

Primary Pigmented Nodular Adrenocortical Disease

The classic symptoms of Cushing's syndrome include rapid central weight gain, a puffy red face and a buffalo hump at the back of the neck due to fat deposits. [en.wikipedia.org]

On clinical examination, skin atrophy, buffalo hump, moon facies, proximal muscle weakness and elevated blood pressure (145/90 mmHg) were documented. [jmedicalcasereports.biomedcentral.com]

For Cushing's syndrome ( glucocorticoid excess) these include weight gain, muscle wasting, purple lines on the abdomen, a fatty " buffalo hump " on the neck, a "moonlike" [en.wikipedia.org]

Pituitary Disorder

There is a characteristic appearance in many patients with Cushing's disease which includes a round face, excess fat pad in the back of the neck ("buffalo hump"), excess fat [emoryhealthcare.org]

Cushing's disease : Cushing's syndrome, or hypercortisolism, is a condition that is characterized by a fatty hump between the shoulders (called a buffalo hump), a rounded [naturallivingcenter.net]

[…] a buffalo hump), fatigue, muscle weakness, rounded face (often called moon face), facial flushing, thin and fragile skin that bruises easily, depression, anxiety, irritability [naturallivingcenter.net]

Adenoma

Symptoms of Cushing’s disease: Weight gain Roundness and fullness of the face (moon facies) Excess fat on the back of the neck (buffalo hump) Purple stretch marks on the abdomen [innerbody.com]

hump), thin skin with striae, hirsutism Nelson's syndrome : hyperpigmentation and muscle weakness TSH ( hyperthyroid symptoms Other hormonal tumors are rare Diagnosis [ edit [en.wikibooks.org]

The clinical features of Cushing disease include central obesity, moon facies, 'buffalo hump,' diabetes, hypertension, fatigue, easy bruising, depression, and reproductive [omim.org]

Thrombocytopenia

At presentation, physical findings showed Cushingoid appearance, with moon face, hyperpigmentation, easy bruising and buffalo hump. [endocrine-abstracts.org]

Renal Adenoma

Cushing's syndrome is characterized by hypertension, moon-shaped face, proximal muscle weakness, truncal obesity, buffalo hump, thin skin, abdominal striae and easy bruising [aafp.org]

The association with facial rounding (“moon face”) and supraclavicular and dorsocervical fat pads (“buffalo hump”) is less strong as these can be seen in obesity from other [clinicaladvisor.com]

hump, striae, proximal muscle weakness, truncal obesity, thin skin, easy bruising 24-hour urinary free cortisol measurement or dexamethasone suppression test Pheochromocytoma [aafp.org]