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66 Possible Causes for Buffalo Hump, Estrogen Increased

  • Adrenocortical Carcinoma

    Testosterone and other androgens: increased facial and body hair, particularly in females deepened voice in females Estrogen: early signs of puberty in children enlarged breast[healthline.com] Symptoms of increased cortisol or other adrenal gland hormones may include: Fatty, rounded hump high on the back just below the neck ( buffalo hump ) Flushed, rounded face[nlm.nih.gov] […] tumor makes extra estrogens, and can create breast growth and impotence in men An adrenal tumor that creates extra adrenaline is a pheochromocytoma.[dartmouth-hitchcock.org]

  • Endocrine Dysfunction

    Key features are central fat deposition resulting in a moon face, fat deposition over the clavicles and upper spine ("buffalo hump") and around the abdomen with production[diapedia.org] Melasma has also been described among men, especially with low testosterone and increased LH levels or taking exogenous estrogens .[omicsonline.org] hump -increased facial hair in women Etiologies of Addisons disease -autoimmune -secondary insufficiency due to pituitary or hypothalamic disorder -withdrawal of steroid[quizlet.com]

  • Iatrogenic Cushing's Disease

    Use of estrogen containing OCPs can contribute to false positive dexamethasone suppression test due to increased cortisol binding globulin and may be discontinued prior to[hopkinsguides.com] View of buffalo hump, on the patient’s neck. F ig . 2. View of buffalo hump, on the patient’s neck.[academic.oup.com] These effects include redistribution of fat resulting in moon face and centripetal obesity, glucocorticoid acne, buffalo hump, thinning of the skin, and purple striae.[symptoma.com]

  • Cushing's Disease

    In addition to the typical clinical symptoms such as moon face,buffalo hump,and central obesity,the CD patients may also experience mental disorders and cognitive dysfunction[ncbi.nlm.nih.gov] […] cortisol binding globulin, such as estrogen.[csrf.net] hump" a red, puffy, rounded face Other symptoms include: skin that bruises easily large purple stretch marks weakness in your upper arms and thighs a low libido and fertility[nhs.uk]

  • Adrenal Cortex Hormone

    The symptoms may include weight gain and fatty deposits in certain areas of the body, such as the face, below the back of the neck called a buffalo hump and in the abdomen[hopkinsmedicine.org] This imitates estrogen's good effects on bone density, without some of the increased cancer risks. Hot flashes are a common side effect.[cedars-sinai.edu] Adverse effects of systemic steroids Effects on body fat Redistribution of body fat: moon face, buffalo hump, truncal obesity Weight gain: increased appetite and food intake[dermnetnz.org]

  • ACTH-Independent Cushing Syndrome

    hump or dorsocervical fat pad Enlarged fat pads in the supraclavicular fossa Truncal obesity Generalized obesity Facial plethora Wasting in the extremities Acne Easy bruising[specialty.mims.com] Urine free cortisol is not increased in simple obesity, high estrogen states or by drugs such as phenytoin.[clinlabnavigator.com] Medications that increase corticosteroid-binding globulin, such as estrogen and tamoxifen, may cause appropriate increases in cortisol levels.[aippg.net]

  • Obesity

    For cancer, the production of estrogens by the enlarged stromal mass plays a role in the risk for breast cancer.[ncbi.nlm.nih.gov] One explanation for the increased risk of endometrial cancer in overweight women is the increased production of estrogens by adipose tissue stromal cells.[doi.org] Increased cytokine release may play a role in other forms of proliferative growth.[ncbi.nlm.nih.gov]

  • Cushing Syndrome

    On examination, the child had central obesity, moon facies, and buffalo hump.[ncbi.nlm.nih.gov] Other hormonal changes are involved including growth hormone, testosterone in men and estrogen in women, catecholamines and cytokines.[ncbi.nlm.nih.gov] hump Have weak muscles or bones, including osteoporosis, bone pain, and fractures Show skin changes, including: Acne or skin infections Reddish-purple stretch marks called[web.archive.org]

  • Adrenal Cushing Syndrome

    A feminizing adrenal tumor makes excess estrogen.[uofmhealth.org] It causes characteristic symptoms including obesity of the trunk and thinning of the extremities, a thickening at the base of neck called a buffalo hump, a rounding of the[surgery.med.miami.edu] The clinical suspicion of Cushing's arises from clinical signs such as thin skin, bruising, hypertension, 'buffalo hump', plethora, moon face, purple striae, and proximal[endocrinesurgeon.co.uk]

  • ACTH-Dependent Cushing Syndrome

    Urine free cortisol is not increased in simple obesity, high estrogen states or by drugs such as phenytoin.[clinlabnavigator.com] It causes characteristic symptoms including obesity of the trunk and thinning of the extremities, a thickening at the base of neck called a buffalo hump, a rounding of the[surgery.med.miami.edu] 1. elevated CBG (estrogens): bind cortisol, test measures free and bound 2. increased dexamehsone metabolism (antiseizure meds) What is considered the most useful Cushings[quizlet.com]

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