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124 Possible Causes for Buffalo Hump, Estrogen Increased

  • Adrenocortical Carcinoma

    Symptoms of increased cortisol or other adrenal gland hormones may include: Fatty, rounded hump high on the back just below the neck ( buffalo hump ) Flushed, rounded face[medlineplus.gov] Testosterone and other androgens: increased facial and body hair, particularly in females deepened voice in females Estrogen: early signs of puberty in children enlarged breast[healthline.com] Symptoms Symptoms of increased cortisol or other adrenal gland hormones may include: Fatty, rounded hump high on the back just below the neck ( buffalo hump ) Flushed, rounded[ufhealth.org]

  • Obesity

    For cancer, the production of estrogens by the enlarged stromal mass plays a role in the risk for breast cancer.[ncbi.nlm.nih.gov] Fat tissue is important in the production of estrogen, and prolonged exposure to high levels of estrogen increases the risk of breast cancer.[medicinenet.com] Increased cytokine release may play a role in other forms of proliferative growth.[ncbi.nlm.nih.gov]

  • Cushing Syndrome

    hump"), increased supraclavicular fat pads, and white abdominal striae.[ncbi.nlm.nih.gov] Other hormonal changes are involved including growth hormone, testosterone in men and estrogen in women, catecholamines and cytokines.[ncbi.nlm.nih.gov] On examination, the child had central obesity, moon facies, and buffalo hump.[ncbi.nlm.nih.gov]

  • Cushing's Disease

    In addition to the typical clinical symptoms such as moon face,buffalo hump,and central obesity,the CD patients may also experience mental disorders and cognitive dysfunction[ncbi.nlm.nih.gov] […] cortisol binding globulin, such as estrogen.[csrf.net] She did not have a Cushingoid appearance, such as a moon-face, buffalo hump, purple striae or central obesity.[ncbi.nlm.nih.gov]

  • Iatrogenic Cushing's Disease

    View of buffalo hump, on the patient’s neck. F ig. 2. View of buffalo hump, on the patient’s neck.[academic.oup.com] Use of estrogen containing OCPs can contribute to false positive dexamethasone suppression test due to increased cortisol binding globulin and may be discontinued prior to[hopkinsguides.com] Plasma cortisol may be spuriously elevated in patients with congenital increases of corticosteroid-binding globulinor in those receiving estrogen therapy, but diurnal variation[physio-pedia.com]

  • Adrenal Cushing Syndrome

    It causes characteristic symptoms including obesity of the trunk and thinning of the extremities, a thickening at the base of neck called a buffalo hump, a rounding of the[surgery.med.miami.edu] A feminizing adrenal tumor makes excess estrogen.[uofmhealth.org] The clinical suspicion of Cushing's arises from clinical signs such as thin skin, bruising, hypertension, 'buffalo hump', plethora, moon face, purple striae, and proximal[endocrinesurgeon.co.uk]

  • ACTH-Dependent Cushing Syndrome

    It causes characteristic symptoms including obesity of the trunk and thinning of the extremities, a thickening at the base of neck called a buffalo hump, a rounding of the[surgery.med.miami.edu] Urine free cortisol is not increased in simple obesity, high estrogen states or by drugs such as phenytoin.[clinlabnavigator.com] […] thin skin, poor wound healing, hirsutism or scalp thinning; pigmentation (usually sign of ACTH dependent Cushings) Weight gain/central obesity (97%); dorsocervical fat pad (buffalo[dundeemedstudentnotes.wordpress.com]

  • Adrenal Gland Neoplasm

    Most patients present with features of glucocorticoid excess (Cushing's syndrome), which includes central obesity, peripheral weakness, abdominal striae, buffalo hump, hirsutism[surgwiki.com] Estrogen: may increase due to production of the hormone by the adrenal tumor.[news-medical.net] Men with tumors that cause increases in estrogen may notice breast enlargement or breast tenderness.[healthline.com]

  • ACTH-Independent Cushing Syndrome

    hump or dorsocervical fat pad Enlarged fat pads in the supraclavicular fossa Truncal obesity Generalized obesity Facial plethora Wasting in the extremities Acne Easy bruising[specialty.mims.com] Urine free cortisol is not increased in simple obesity, high estrogen states or by drugs such as phenytoin.[clinlabnavigator.com] Medications that increase corticosteroid-binding globulin, such as estrogen and tamoxifen, may cause appropriate increases in cortisol levels.[aippg.net]

  • Corticotroph Pituitary Adenoma

    […] features 6 : rounded face, sometimes described as 'moon-shaped' progressive centripetal obesity and weight gain prominent supraclavicular fat pad, sometimes known as a 'buffalo[radiopaedia.org] increase in cortisol binding globulin (CBG) levels and an increase in cortisol production.[clinicaladvisor.com] […] signs of Cushings syndrome and disease may include: Change in body habitus: weight gain in face (moon face), above the collar bone (supraclavicular) and on back of neck (buffalo[pituitary.org]

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