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171 Possible Causes for Buffalo Hump, Insulin Resistance

  • Endocrine Dysfunction

    Key features are central fat deposition resulting in a moon face, fat deposition over the clavicles and upper spine ("buffalo hump") and around the abdomen with production[diapedia.org] The pathogenesis of diabetes is still relatively unclear, but the main mechanisms include the loss of insulin secretory capacity and insulin resistance secondary to liver[ncbi.nlm.nih.gov] hump -increased facial hair in women Etiologies of Addisons disease -autoimmune -secondary insufficiency due to pituitary or hypothalamic disorder -withdrawal of steroid[quizlet.com]

  • Lipodystrophy

    It can manifest as a loss of fat in legs, arms, face or buttocks or even by an accumulation of fat in the belly, on breasts/chest or at the nape of the neck (buffalo hump)[hug-ge.ch] Measurements of insulin resistance IR was defined by the homeostasis model assessment of insulin resistance (HOMA) and insulin sensitivity by the quantitative insulin sensitivity[bmcinfectdis.biomedcentral.com] Liposuction is often explored for the removal of accumulated fat around the back of the neck (commonly referred to as a "buffalo hump").[aids.about.com]

  • Obesity

    The aim of this paper is to analyze the pathogenetic mechanisms of insulin resistance development in pregnant women with varying obesity degrees in early and late gestation[ncbi.nlm.nih.gov] Obesity is a serious health risk factor strongly associated with insulin resistance and type 2 diabetes; however, the underlying mechanisms associating obesity with insulin[ncbi.nlm.nih.gov] Serum insulin levels were measured using enzyme-linked immunosorbent assay (ELISA), and insulin resistance was calculated using the homeostasis model assessment of insulin[ncbi.nlm.nih.gov]

  • Generalized Lipodystrophy

    hump[glosbe.com] insulin receptors exists and contributes to insulin resistance in the patient.[ncbi.nlm.nih.gov] Studies on insulin receptors of circulating mononuclear leucocytes indicated that insulin-resistant diabetes combined with congenital generalized lipodystrophy may be due[ncbi.nlm.nih.gov]

  • Familial Partial Lipodystrophy

    A “ buffalo hump ” can be observed between the shoulder blades. The arms and legs appear very muscular. In women, lack of fat in the buttocks is striking — flat hips .[manbironline.com] The findings in FPLD indicate that defective structure of the nuclear envelope produces a phenotype of insulin resistance.[ncbi.nlm.nih.gov] Some patients at the same time .gain excess fat at the the face, chin (double chin), and neck (Cushingoid appearance with buffalo hump).[het-werner-syndroom.com]

  • Morbid Obesity

    […] to assess insulin resistance among morbidly obese subjects.[ncbi.nlm.nih.gov] Visceral adiposity is associated with decreased serum adiponectin levels, peripheral resistance to insulin and an increased risk of cardio-metabolic complications.[ncbi.nlm.nih.gov] To investigate 1) differences in cardiometabolic risk and HOMA of insulin resistance (HOMA-IR) across BMI categories (underweight to morbid obesity), 2) whether fit children[ncbi.nlm.nih.gov]

  • Corticotropin

    hump") Thinning skin that is easy to bruise Acne Being very tired Weak muscles, especially when using your shoulders and hip muscles High blood pressure High blood sugar[webmd.com] To present a case of a young woman with new-onset diabetes mellitus resistant to insulin attributable to Cushing's syndrome caused by ectopic production of corticotropin by[ncbi.nlm.nih.gov] Induces insulin resistance, promotes a proinflammatory profile and stimulates UCP-1 in adipocytes in vitro .[rndsystems.com]

  • Pediatric Hypertension

    Moon facies, truncal obesity, buffalo hump (Thyromegaly, Proptosis, hyperdynamic circulation…….. (Hyperthyroidism Signs of meningeal irritation,…………………… CNS Infections.[slideshare.net] We present updates on the complex interactions of these two systems with dietary salt intake in relation to obesity, insulin resistance, inflammation, and oxidative stress[ncbi.nlm.nih.gov] Children (and adults) who are overweight or obese are more likely to have risk factors for heart disease like hypertension, high cholesterol, diabetes, insulin resistance[hopkinsmedicine.org]

  • Hypernatremia

    History and clinical examination, the latter demonstrating features of syndrome, e.g. hypertension, buffalo hump, striae, truncal obesity, plethora, are important clues.[tcd.ie] High-dose glucocorticoid, insulin resistance, and a postsurgical catabolic stress likely contributed.[ncbi.nlm.nih.gov] resistance and impairs hepatic neoglucogenesis [ 24 ].[bmcnephrol.biomedcentral.com]

  • Endometrial Hyperplasia

    The patient's striae, weight gain, and buffalo hump markedly improved, and further bone loss was halted.[ncbi.nlm.nih.gov] However, little is known about the prevalence of abnormal glucose metabolism and insulin resistance (IR) in EC patients.[ncbi.nlm.nih.gov] Insulin resistance might play a role in the occurrence of atypical endometrial hyperplasia complicating PCOS.[ncbi.nlm.nih.gov]

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