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12 Possible Causes for Bullous Rash, Chills, Degeneration of Epidermal Basal Cells

  • Vasculitis

    Abstract A previously healthy 77-year-old Japanese man presented with a 2-week history of daily fevers peaking at 38 C, chills, hearing loss, and almost 10 kg of unintentional[ncbi.nlm.nih.gov] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[dermnetnz.org] After completion of 4 cycles of ipilimumab for the treatment of metastatic melanoma, our patient complained of increasing fatigue, drenching night sweats, and chills.[ncbi.nlm.nih.gov]

  • Erythema Multiforme

    Systemic side effects of PCV13 include chills, fever, headache, vomiting, fatigue, arthralgia, myalgias, decreased appetite, and diarrhea, whereas its cutaneous adverse reactions[ncbi.nlm.nih.gov] Acquired rashes in the older child. In: Kleigman RM, Lye PS, Bordini BJ, Toth H, Basel D, eds. Nelson Pediatric Symptom-Based Diagnosis.[nlm.nih.gov] Pathologic findings include liquefactive degeneration of the basal epidermal cells, necrotic keratinocytes, and exocytosis of lymphocytes.[onlinelibrary.wiley.com]

  • Epidermolysis Bullosa

    Fever or chills. If you get an infection, your doctor may treat it with: A soaking liquid. An antibiotic cream or pill. A special covering (for sores that don’t heal).[niams.nih.gov] […] layer caused by degeneration of individual epidermal cells Dystrophic EB: pretibial lesion Electron microscopy description Electron microscopy images Images hosted on other[pathologyoutlines.com] […] servers: EB simplex: epidermal basal keratinocytes Back to top[pathologyoutlines.com]

  • Graft-versus-Host-Disease

    Photo Credit Dolly Faibyshev for The New York Times Work Out and Chill?[nytimes.com] […] nausea, vomiting, or anorexia, with a positive upper GI biopsy result 2 Maculopapular rash 25%-50% BSA 3.1-6 mg/dL 1000-1500 mL/d (Child: 20-30 mL/kg/d) 3 Maculopapular rash[clinicaladvisor.com] Skin biopsies were consistent with GVHD, showing vacuolar degeneration of the basal layer of the epithelium, epidermal infiltration by lymphocytes and necrotic eosinophilic[ncbi.nlm.nih.gov]

  • Pityriasis Circinata

    Especially in children Other symptoms present in only 5% of patients Viral prodrome-type constitutional symptoms may occur with mild URI symptoms Headache Malaise Arthralgia s Chills[fpnotebook.com] The lesions may be punctate, erosive, bullous or hemorrhagic. They disappear concomitantly as the skin eruption fades.[wjgnet.com] Besides, histology shows epidermal atrophy and basal layer degeneration.[wjgnet.com]

  • Lupus Erythematosus

    Side effects Common side effects of belimumab include: flu-like symptoms, such as chills and a high temperature nausea and diarrhoea headache difficulty sleeping ( insomnia[nhsinform.scot] Bullous rash and brown urine in a systemic lupus erythematous patient treated with hydroxychloroquine. Arthritis Rheum 1995 ; 38 : 440 –443 15 Gibson GE, McEvoy MT.[academic.oup.com] […] of basal cells; 4) a predominantly lymphocytic infiltrate along the dermal-epidermal junction, around the fair follicles and eccrine ducts, in an interstitial pattern; 14[scielo.br]

  • Systemic Lupus Erythematosus

    We highlight the case of a 61year-old male with complaints of acute onset shortness of breath and generalized body aches associated with a fever and chills in the ER.[ncbi.nlm.nih.gov] An uncommon but serious form of lupus rash results in the development of large blisters and is called a "bullous" lupus rash. Joints.[webmd.com] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com]

  • Rare Cutaneous Lichen Planus

    I try to chill out and keep my stress levels down by going for massages and doing yoga. After all, there are people out there with worse things."[your.md] Blistering (bullous) lichen planus is rare and usually affects the lower legs.[britishskinfoundation.org.uk] There is a T-cell infiltrate at the dermo-epidermal junction, with vacuolar or liquefactive degeneration of the basal cells of the epidermis.[news-medical.net]

  • Erythema Annulare Centrifugum

    There may be symptoms - such as night sweats, fever and chills - of underlying diseases (eg, Hodgkin's lymphoma or TB).[patient.info] ) - Diaper rash - Urushiol-induced contact dermatitis - Contact dermatitis - Erythroderma - Lichen simplex chronicus - Prurigo nodularis - Itch - Pruritus ani - Nummular dermatitis[bionity.com] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[ijpd.in]

  • Erythema Marginatum

    Often there are also systemic symptoms, including chills, fever, headache, vomiting, backache, and stiff neck.[medical-dictionary.thefreedictionary.com] Acquired rashes in the older child. In: Kleigman RM, Lye PS, Bordini BJ, Toth H, Basel D, eds. Nelson Pediatric Symptom-Based Diagnosis.[medlineplus.gov] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[ijpd.in]

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