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11 Possible Causes for Bullous Rash, Degeneration of Epidermal Basal Cells, Elevated Sedimentation Rate

  • Vasculitis

    Their results will generally show signs of inflammation in the body, such as increased erythrocyte sedimentation rate (ESR), elevated C-reactive protein (CRP), anemia, increased[en.wikipedia.org] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[dermnetnz.org] The univariate analysis demonstrated a significant association between systemic vasculitic involvement and elevated erythrocyte sedimentation rate (cRR, 4.15), leukocytosis[jamanetwork.com]

  • Erythema Multiforme

    Acquired rashes in the older child. In: Kleigman RM, Lye PS, Bordini BJ, Toth H, Basel D, eds. Nelson Pediatric Symptom-Based Diagnosis.[nlm.nih.gov] Laboratory Findings Laboratory findings are non-specific and can include an elevated erythrocyte sedimentation rate ( ESR ), elevated white blood cell count ( WBC ), and elevated[wikidoc.org] Pathologic findings include liquefactive degeneration of the basal epidermal cells, necrotic keratinocytes, and exocytosis of lymphocytes.[onlinelibrary.wiley.com]

  • Systemic Lupus Erythematosus

    An uncommon but serious form of lupus rash results in the development of large blisters and is called a "bullous" lupus rash. Joints.[webmd.com] Initial labs showed pancytopenia, bandemia, proteinuria, elevated erythrocyte sedimentation rate, and elevated d-dimer.[ncbi.nlm.nih.gov] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com]

  • Lupus Erythematosus

    Bullous rash and brown urine in a systemic lupus erythematous patient treated with hydroxychloroquine. Arthritis Rheum 1995 ; 38 : 440 –443 15 Gibson GE, McEvoy MT.[academic.oup.com] The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.[fpnotebook.com] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com]

  • Discoid Lupus Erythematosus

    An uncommon but serious form of lupus rash results in the development of large blisters and is called a "bullous" lupus rash. Joints.[webmd.com] rate will be elevated Rheumatoid factor- may be positive Urinalysis – Urine test may show involvement of kidneys.[steadyhealth.com] A skin biopsy from her cheek revealed hyperkeratosis, focal epidermal atrophy, basal cell degeneration and dilated follicular orifices filled with compact keratin.[ncbi.nlm.nih.gov]

  • Chilblain Lupus Erythematosus

    […] on arms, sometimes forming large plaques and spreading widely Photosensitivity (a rash on all recently sun- exposed skin ) Cheilitis and mouth ulcers Blisters ( bullous LE[dermnetnz.org] A faster than normal rate may indicate a systemic disease, such as lupus. The sedimentation rate isn’t specific for any one disease.[healthjade.com] In particular, skin histopathology of DLE shows classical features: vacuolar degeneration of basal cell layer; thickened basement membrane; orthokeratosis with follicular[ped-rheum.biomedcentral.com]

  • Chronic Lichenoid Pityriasis

    […] and eczema Atopic dermatitis · Seborrhoeic dermatitis ( Dandruff, Cradle cap ) · Contact dermatitis ( Diaper rash, Urushiol-induced contact dermatitis ) · Erythroderma ·[wikidoc.org] sedimentation rate. 6 Unfortunately, even though electron microscopy shows some viral changes and possible viral particles, antibody and polymerase chain reaction tests for[aafp.org] Epidermal changes include spongiosis and, characteristically, vacuolar degeneration of stratum basale. [22] Lymphocytic exocytosis into the epidermis is seen in EM as also[e-ijd.org]

  • Erythema Annulare Centrifugum

    ) - Diaper rash - Urushiol-induced contact dermatitis - Contact dermatitis - Erythroderma - Lichen simplex chronicus - Prurigo nodularis - Itch - Pruritus ani - Nummular dermatitis[bionity.com] FBC, erythrocyte sedimentation rate (ESR) and CXR may be useful in excluding malignancy. Lyme antibody titre to exclude erythema migrans may be appropriate.[patient.info] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[ijpd.in]

  • Erythema Marginatum

    Acquired rashes in the older child. In: Kleigman RM, Lye PS, Bordini BJ, Toth H, Basel D, eds. Nelson Pediatric Symptom-Based Diagnosis.[medlineplus.gov] Moreover other objective findings, such as elevation of erytrocyte sedimentation rate or C-reactive protein and a prolonged P-R interval on ECG can be detected.[dermatologyadvisor.com] Histopathology demonstrates epidermal atrophy, basal cell degeneration, and mononuclear cell infiltrate in the dermis.[ijpd.in]

  • Bullous Systemic Lupus Erythematosus

    […] to form painful desquamating bullous lesions filled with serous fluid.[the-rheumatologist.org] The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of le cells in the blood or bone marrow.[icd10data.com] […] of the epidermal basal layer.[mussenhealth.us]