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20 Possible Causes for Bullous Rash, Degeneration of Epidermal Basal Cells, Eruptions

  • Erythema Multiforme

    We report a case of an erythema multiforme drug eruption associated with erythrodermic psoriasis induced by SOF and DCV.[ncbi.nlm.nih.gov] Acquired rashes in the older child. In: Kleigman RM, Lye PS, Bordini BJ, Toth H, Basel D, eds. Nelson Pediatric Symptom-Based Diagnosis.[nlm.nih.gov] Pathologic findings include liquefactive degeneration of the basal epidermal cells, necrotic keratinocytes, and exocytosis of lymphocytes.[onlinelibrary.wiley.com]

  • Graft-versus-Host-Disease

    […] report the case of a 56-year-old male with a history of relapsed follicular lymphoma status post allogenic bone marrow transplant who developed severe diarrhea with a skin eruption[ncbi.nlm.nih.gov] […] nausea, vomiting, or anorexia, with a positive upper GI biopsy result 2 Maculopapular rash 25%-50% BSA 3.1-6 mg/dL 1000-1500 mL/d (Child: 20-30 mL/kg/d) 3 Maculopapular rash[clinicaladvisor.com] Skin biopsies were consistent with GVHD, showing vacuolar degeneration of the basal layer of the epithelium, epidermal infiltration by lymphocytes and necrotic eosinophilic[ncbi.nlm.nih.gov]

  • Vasculitis

    Drug eruption was been confirmed by means of a challenge test, together with histopathological and clinical findings.[ncbi.nlm.nih.gov] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[dermnetnz.org] We describe a unique case of a cocaine user who presented with an acute purpuric eruption and negative ANCA laboratory findings.[ncbi.nlm.nih.gov]

  • Pityriasis Circinata

    Gianotti-Crosti syndrome, pityriasis rosea, asymmetrical periflexural exanthem, unilateral mediothoracic exanthem, eruptive pseudoangiomatosis and papular-purpuric gloves[doi.org] The lesions may be punctate, erosive, bullous or hemorrhagic. They disappear concomitantly as the skin eruption fades.[wjgnet.com] Pityriasis Rosea (PR) History:(i) Close contacts with similar eruptions: Mostly uncommon because most cases of PR are sporadic(ii) Medication intake: Could cause a similar[dailyrounds.org]

  • Discoid Lupus Erythematosus

    We describe a unique case of eruptive keratoacanthomatous scaly papules in a 56-year-old woman with discoid lupus erythematosus.[ncbi.nlm.nih.gov] An uncommon but serious form of lupus rash results in the development of large blisters and is called a "bullous" lupus rash. Joints.[webmd.com] […] hydropic degeneration of the basal cell layer, thickening of the basement membrane zone, telangiectasia, superficial and deep perivascular and periadnexal lymphocytic inflammatory[scielo.br]

  • Epidermolysis Bullosa

    We report the case of a 60-year-old Japanese woman with persistent blistering eruptions and scar formation on the pretibial region and elbows.[ncbi.nlm.nih.gov] […] layer caused by degeneration of individual epidermal cells Dystrophic EB: pretibial lesion Electron microscopy description Electron microscopy images Images hosted on other[pathologyoutlines.com] Bullosa, bullosa epidermolysis, epidermolysis bullosa, epidermolysis bullosa (diagnosis), Epidermolysis bullosa, Acantholysis bullosa, Acanthosis bullosa, Bullous recurrent eruption[fpnotebook.com]

  • Actinic Lichen Planus

    , polymorphous light eruption, and erythema dyschronicum perstans. 5 The clinician also must exclude the possibility of a drug-induced photosensitive lichenoid eruption by[mdedge.com] Bullous: Fluid-filled blisters and lesions that can occur in the mouth, genitals, lower limbs and trunk.[draxe.com] Histology classically demonstrates hyperkeratosis, epidermal thinning, vacuolar degeneration of the basal cell layer, lymphohistiocytic band-like infiltrate, variable Civatte[jcadonline.com]

  • Bullous Lichen Planus

    There were significant differences between familial and non-familial BLP in age of onset, duration of disease and extension of eruption (P[ncbi.nlm.nih.gov] Dermatological adverse events such as pruritus and rash have been reported in various clinical trials.[ncbi.nlm.nih.gov] Degeneration of basal epidermal cells leads to exposure of the basement membrane antigens.[jemds.com]

  • Cutaneous Lupus Erythematosus

    Abstract Hydroxyurea is a medication with many well-described cutaneous side effects, notably the dermatomyositis-like eruption known as hydroxyurea dermopathy.[ncbi.nlm.nih.gov] Abstract A 29-year-old woman with a 1.5 year history of photosensitive skin lesions on her hands presented with a malar rash, bullous lesions on her hands, and was diagnosed[ncbi.nlm.nih.gov] […] of basal cells; 4) a predominantly lymphocytic infiltrate along the dermal-epidermal junction, around the fair follicles and eccrine ducts, in an interstitial pattern; 14[scielo.br]

  • Rare Cutaneous Lichen Planus

    Lichenoid drug eruption (drug-induced lichen planus). Corona, R. (Ed.), UpToDate. topic last updated: Jan 09, 2018. Accessed September 10, 2018 June 25, 2018.[rarediseases.org] Blistering (bullous) lichen planus is rare and usually affects the lower legs.[britishskinfoundation.org.uk] There is a T-cell infiltrate at the dermo-epidermal junction, with vacuolar or liquefactive degeneration of the basal cells of the epidermis.[news-medical.net]

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