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19 Possible Causes for Bullous Rash, Degeneration of Epidermal Basal Cells, Rheumatoid Arthritis

  • Vasculitis

    A patient with a history of rheumatoid arthritis presented with bilateral orbital lesions while on abatacept.[ncbi.nlm.nih.gov] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[dermnetnz.org] The best described of these is vasculitis occurring as a complication of rheumatoid arthritis (see below).[nras.org.uk]

  • Erythema Multiforme

    We present a case of a woman with a 14-year history of rheumatoid arthritis, who showed simultaneously and gradually appearing, annular, erythematous, itchy patches and exacerbation[ncbi.nlm.nih.gov] Acquired rashes in the older child. In: Kleigman RM, Lye PS, Bordini BJ, Toth H, Basel D, eds. Nelson Pediatric Symptom-Based Diagnosis.[nlm.nih.gov] Pathologic findings include liquefactive degeneration of the basal epidermal cells, necrotic keratinocytes, and exocytosis of lymphocytes.[onlinelibrary.wiley.com]

  • Systemic Lupus Erythematosus

    OBJECTIVES: In 2004 and 1999, respectively, recent-onset rheumatoid arthritis (RA) and systemic lupus erythematous (SLE) cohorts were initiated; the 36 item Medical Outcome[ncbi.nlm.nih.gov] An uncommon but serious form of lupus rash results in the development of large blisters and is called a "bullous" lupus rash. Joints.[webmd.com] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com]

  • Graft-versus-Host-Disease

    CBD has shown benefit in a number of models of inflammatory diseases including diabetes 8 , rheumatoid arthritis 9 , multiple sclerosis 10 , and inflammatory bowel disease[kalytera.co] […] nausea, vomiting, or anorexia, with a positive upper GI biopsy result 2 Maculopapular rash 25%-50% BSA 3.1-6 mg/dL 1000-1500 mL/d (Child: 20-30 mL/kg/d) 3 Maculopapular rash[clinicaladvisor.com] Skin biopsies were consistent with GVHD, showing vacuolar degeneration of the basal layer of the epithelium, epidermal infiltration by lymphocytes and necrotic eosinophilic[ncbi.nlm.nih.gov]

  • Lupus Erythematosus

    arthritis (RA), as well as many of the drugs in the therapeutic pipeline, reduce the autoimmune inflammatory process but lead to a general immunosuppression.[stm.sciencemag.org] Bullous rash and brown urine in a systemic lupus erythematous patient treated with hydroxychloroquine. Arthritis Rheum 1995 ; 38 : 440 –443 15 Gibson GE, McEvoy MT.[academic.oup.com] […] of basal cells; 4) a predominantly lymphocytic infiltrate along the dermal-epidermal junction, around the fair follicles and eccrine ducts, in an interstitial pattern; 14[scielo.br]

  • Discoid Lupus Erythematosus

    Previously, a discoid lupus erythematosus-like eruption linked to its use was rarely reported in patients with rheumatoid arthritis.[ncbi.nlm.nih.gov] An uncommon but serious form of lupus rash results in the development of large blisters and is called a "bullous" lupus rash. Joints.[webmd.com] […] hydropic degeneration of the basal cell layer, thickening of the basement membrane zone, telangiectasia, superficial and deep perivascular and periadnexal lymphocytic inflammatory[scielo.br]

  • Cutaneous Lupus Erythematosus

    Case Presentation: 80-year-old male with Rheumatoid Arthritis (RA).[shmabstracts.com] Abstract A 29-year-old woman with a 1.5 year history of photosensitive skin lesions on her hands presented with a malar rash, bullous lesions on her hands, and was diagnosed[ncbi.nlm.nih.gov] […] of basal cells; 4) a predominantly lymphocytic infiltrate along the dermal-epidermal junction, around the fair follicles and eccrine ducts, in an interstitial pattern; 14[scielo.br]

  • Chilblain Lupus Erythematosus

    […] factors – antibodies that are often found in the serum of patients with rheumatoid arthritis – which is also found in SLE patients.[research.bmh.manchester.ac.uk] […] on arms, sometimes forming large plaques and spreading widely Photosensitivity (a rash on all recently sun- exposed skin ) Cheilitis and mouth ulcers Blisters ( bullous LE[dermnetnz.org] In particular, skin histopathology of DLE shows classical features: vacuolar degeneration of basal cell layer; thickened basement membrane; orthokeratosis with follicular[ped-rheum.biomedcentral.com]

  • Chronic Lichenoid Pityriasis

    arthritis. ( 25789178 ) Echeverri A.F....Bonilla-AbadA-a F. 2015 9 Differentiation of pityriasis lichenoides chronica from guttate psoriasis by dermoscopy. ( 25682853 ) Errichetti[malacards.org] Interferon-related injection site (local) reactions -ill-defined, roundish, pruritic, self-recovering erythematous patches (Figure 17) -vesico-bullous rashes -Skin necrosis[intechopen.com] Epidermal changes include spongiosis and, characteristically, vacuolar degeneration of stratum basale. [22] Lymphocytic exocytosis into the epidermis is seen in EM as also[e-ijd.org]

  • Pityriasis Circinata

    Rheumatoid Arthritis Rheumatoid arthritis (RA) is an autoimmune disease. It causes pain, swelling, stiffness, and loss of function in the joints.[uvahealth.com] The lesions may be punctate, erosive, bullous or hemorrhagic. They disappear concomitantly as the skin eruption fades.[ncbi.nlm.nih.gov] Other autoimmune diseases are rheumatoid arthritis, some thyroid diseases, anaemia, lupus, celiac Rheumatoid Arthritis, Cluster Headaches, Dermatomyositis - Online Drugstore[enhance-itn.eu]

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