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68 Possible Causes for Bullous Rash, Nikolsky's Sign

  • Bullous Pemphigoid

    The authors describe, to their knowledge, the first report of gabapentin-induced bullous pemphigoid in an elderly man with no history of rashes or reactions to other medications[] Placing pressure on the bullae do not lead to their extension into underlying skin, and thus the bullae are negative for "Nikolsky Sign".[] Bullous pemphigoid is a condition caused by a malfunctioning immune system that produces large blisters and skin rashes on the abdomen, arms, legs, and in some cases, the[]

  • Pemphigus Vulgaris

    In taking the history, it is also imperative to identify whether the bullae are due to classic (or idiopathic) bullous pemphigoid or due to drug-induced bullous pemphigoid[] sign.[] The blisters were suspected to represent the Nikolsky's sign.[]

  • Pemphigus

    Pemphigus herpetiformis (PH) is a rare autoimmune bullous condition usually seen in adults and likely underrecognized in children.[] Nikolsky’s sign Nikolsky s sign was first described by a Russian dermatologist Pyotr Vasilievich Nikolskiy.[] PNP is a rare and often aggressive bullous disease with an autoimmune pathogenesis, associated with underlying lymphoproliferative disease.[]

  • Erythema Multiforme

    Acquired rashes in the older child. In: Kleigman RM, Lye PS, Bordini BJ, Toth H, Basel D, eds. Nelson Pediatric Symptom-Based Diagnosis.[] […] involvement, Nikolsky sign) Urticaria (annular lesions) Erythema nodosum Viral exanthems Treatment Supportive care Corticosteroids if severe Treat underlying cause if identified[] Erythema multiforme major is a form of rash with skin loss or epidermal detachment.[]

  • Bullous Impetigo

    Bullous Impetigo Duration Bullous Impetigo rashes usually take a few weeks to resolve completely.[] sign (sheet-like removal of epidermis with sliding pressure) Highly contagious; may occur in outbreaks ( Antonie Van Leeuwenhoek 2009;95:387, Euro Surveill 2009;14:19372[] sign Localization Face (most common), especially around the nose and mouth Extremities May be pruritic (especially pustules ) but is rarely painful Regional lymphadenopathy[]

  • Toxic Epidermal Necrolysis

    The rash rapidly progresses to become vesicular and bullous on the face and body.[] sign.[] rash strongly indicating toxic epidermal necrolysis associated with the use of intravenous ritodrine hydrochloride, Journal of Obstetrics and Gynaecology Research, 36, 3,[]

  • Staphylococcal Scalded Skin Syndrome

    rash without exfoliation to generalized exfoliative disease was observed in 17 children.[] […] acute illness in which the Nikolsky's sign can be easily elicited.[] The erythema is followed by cleavage of the upper epidermis in a large sheets mainly in the head, neck and the flexures, with formation of bullae (Nikolsky sign).[]

  • Epidermolysis Bullosa Acquisita

    Nikolsky's sign and bulla spreading sign were positive. Minimal atrophy and pigmentary disturbances were evident on healing. Milia were absent.[] Nikolsky’s sign was positive. In addition, mucosal lesions appeared on the tongue and lips.[] The Nikolsky and Asboe-Hansen signs (see above) are positive. The crusted lesions may follow an arcuate pattern. Healing occurs without scarring.[]

  • Epidermolysis Bullosa

    Epidermolysis bullosa is defined as a group of rare hereditary skin diseases, characterized by the formation of blisters following trivial trauma. The presentation and primary symptoms of all subtypes of epidermolysis bullosa are similar. However the age at onset, dermal layer involved, severity and extent of[…][]

  • Extensive Burns

    Abstract Classic determinants of burn mortality are age, burn size, and the presence of inhalation injury. Our objective was to describe temporal trends in patient and burn characteristics, inpatient mortality, and the relationship between these characteristics and inpatient mortality over time. All patients aged 18[…][]

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