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205 Possible Causes for Bull's Eye Maculopathy, Severely Reduced Central Responses on Multifocal ERG

  • Macular Dystrophy with Central Cone Involvement

    ERG responses to full-field testing are normal but multifocal studies reveal severely reduced central responses.[disorders.eyes.arizona.edu] Fundus anomalies are variable and include bull's eye maculopathy, severe atrophy of central fovea, relatively spared fovea with surrounding atrophic ring, central retinal[uniprot.org] Differential Diagnosis A 31-year-old Chinese male presents with acutely symptomatic decrease in vision in his left eye with a ipsilateral bulls eye maculopathy.[westcoastretina.com]

  • Occult Macular Dystrophy

    The fundi of 12 patients were essentially normal (occult macular dystrophy), and the oldest patient in one family disclosed bull's eye maculopathy.[ncbi.nlm.nih.gov] The multifocal ERGs 4 demonstrated a loss of local responses in the central retina (fig 2C).[bjo.bmj.com] ABCA4 - Bull's eye maculopathie This test is available for the following conditions: Conditions Vision impairment / blindness Macula dystrophy This product is also part of[order.radboudumc.nl]

  • Toxic Retinopathy

    The first patient had bull's eye maculopathy confirmed with visual field testing and optical coherence tomography (OCT).[ncbi.nlm.nih.gov] […] zone of hypopigmentation around both fovea, which was consistent with toxic chloroquine retinopathy, or bilateral bull's-eye maculopathy (Panel A, right eye; Panel B, left[nejm.org] ’s eye maculopathy, and vitelliform maculopathy have been described. 2– , 8 We report a patient who had rapid development of irreversible diffuse pigmentary retinopathy with[bjo.bmj.com]

    Missing: Severely Reduced Central Responses on Multifocal ERG
  • Benign Concentric Annular Macular Dystrophy

    Bull's eye maculopathy and negative electroretinogram.[scielo.br] The fundus showed a bull's-eye maculopathy,Fig. 8 (Van den Biesen, Deutman, and Pinckers).[docslide.net] F igure 2. ( A ) Fundus photograph of patient II-9, age 47 years: Typical bull’s-eye maculopathy and slightly attenuated arterioles; ( B ) fluorescein angiogram of patient[iovs.arvojournals.org]

    Missing: Severely Reduced Central Responses on Multifocal ERG
  • Chloroquine Retinopathy

    […] zone of hypopigmentation around both fovea, which was consistent with toxic chloroquine retinopathy, or bilateral bull's-eye maculopathy (Panel A, right eye; Panel B, left[doi.org] Chloroquine retinopathy, also known as Bull's eye maculopathy, is a form of toxic retinopathy (damage of the retina) caused by the drugs chloroquine or hydroxychloroquine,[en.wikipedia.org] The "bull's eye" maculopathy is considered to be a pathognomonic finding of chloroquine retinopathy, manifesting as loss of central vision, while night blindness, reduced[symptoma.com]

    Missing: Severely Reduced Central Responses on Multifocal ERG
  • Peripheral Cone Dystrophy

    Multifocal electroretinography (mfERG) showed well-preserved local responses in the central retina and severely reduced responses in the perifoveal retina (Fig. 1) corresponding[journals.lww.com] Cone dystrophy refers to a group of genetically heterogeneous disorders ranging from normal to mild pigmentary mottling to bull’s eye maculopathy.[aao.org] The results of mfERGs showed slightly detectable responses in the central area of left eye; however, the amplitudes of the other area were severely reduced in the patients[link.springer.com]

  • Adult-Onset Foveomacular Vitelliform Dystrophy

    […] of 5 patients with a bull's eye maculopathy, but none of the controls, were found to possess amino acid-changing variants in the VMD2 gene.[ncbi.nlm.nih.gov] Assessment of mutations in the best macular dystrophy (VMD2) gene in patients with adult-onset foveomacular vitelliform dystrophy, age-related maculopathy, and bull’s eye[reviewofoptometry.com] ’s eye maculopathy develops.[ophthalmologymanagement.com]

    Missing: Severely Reduced Central Responses on Multifocal ERG
  • Jalili Syndrome

    Fundus exam revealed mild to severe bull’s eye maculopathy in 3/4 and diffuse retinal dystrophy in 1/4 patients.[iovs.arvojournals.org] Ophthalmoscopy revealed macular changes (Bull’s eye maculopathy) and a pale optic disc in both patients.[journals.plos.org] Two phenotypes are proposed: associated with bull’s eye maculopathy and peripheral retinal degeneration (type A) or with minor retinal dystrophy (type B).[iovs.arvojournals.org]

    Missing: Severely Reduced Central Responses on Multifocal ERG
  • Best Disease

    Mutations have been documented in a significant percentage of patients with adult vitelliform macular dystrophy (AVMD) and in a single case of "bull's-eye" maculopathy.[ncbi.nlm.nih.gov] maculopathy.[orpha.net] Assessment of mutations in the Best macular dystrophy (VMD2) gene in patients with adult-onset foveomacular vitelliform dystrophy, age-related maculopathy, and bull's-eye[ncbi.nlm.nih.gov]

    Missing: Severely Reduced Central Responses on Multifocal ERG
  • Neuronal Ceroid Lipofuscinosis 3

    The fundus shows a bull's eye maculopathy, diffuse pigmentary degeneration, arteriolar attenuation and optic atrophy, and an extinguished ERG.[ncbi.nlm.nih.gov] Ophthalmologic examination early in the course of vLINCL (CLN5) may reveal macular changes only; gradually typical signs of pan-retinal degeneration develop: Bull's eye maculopathy[pediatricneurosciences.com] Keywords: autofluorescence ; Batten disease ; bull's eye maculopathy ; CLN3 gene ; juvenile neuronal ceroid lipofuscinosis ; macular dystrophy ; optical coherence tomography[journals.lww.com]

    Missing: Severely Reduced Central Responses on Multifocal ERG

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