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46 Possible Causes for Burning Feet, Folic Acid Deficiency, Macrocytosis

  • Folate-Deficiency Anemia

    Both subjects were African American women with markedly elevated C-reactive protein concentrations, macrocytosis, and normal serum cobalamin concentrations; only one subject[ncbi.nlm.nih.gov] […] caused by a lack of folic acid in the diet. folic acid deficiency anemia Anemia resulting from a deficiency of folic acid.[medical-dictionary.thefreedictionary.com] Nonalcoholic liver disease and hypothyroidism account for a substantial portion of macrocytosis.[aafp.org]

  • Chronic Alcoholism

    Alcohol is a common cause of macrocytosis, with a mean corpuscular volume (MCV) of 100-110 fL seen in a majority of patients.[symptoma.com] People suffering from alcoholic neuropathy may feel burning and tingling sensations in their feet, which may persist or may last from a few months to a few years.[foundationforpn.org] Folic acid and vitamins B6 and B12 deficiency may lead to hyperhomocysteinemia, as they participate in its metabolism.[ncbi.nlm.nih.gov]

  • Malabsorption Syndrome

    In this setting, microcytic anaemia usually implies iron deficiency and macrocytosis can be caused by impaired folic acid or B12 absorption or both.[en.wikipedia.org] […] sensation in legs or feet.[encyclopedia.com] Plasma viscosity (the thickness of the fluid in which blood cells are suspended), vitamin B12 level, red cell folate (folic acid), iron status, and clotting screen for vitamin[puristat.com]

  • Megaloblastic Anemia

    Medication-induced folic acid deficiency.[lpch.org] […] in hands and feet, loss of sensation (e.g. feeling like wearing thin stocking or glove) Unsteady gait and loss of balance: occur in subacute combined spinal cord degeneration[pathologyoutlines.com] Benign familial macrocytosis. Clin Lab Haematol 1996; 18 :41–43. [ PubMed ] 14.[ncbi.nlm.nih.gov]

  • Pellagra

    But it was fetal development that was the principal stimulus, as folic acid deficiency is a principal reason for congenital defects of the nervous system, such as spina bifida[blogs.creighton.edu] Bleeding may result in blackened crusts Lesions may occur anywhere on the body especially the hands, arms, lower legs, feet, face, and neck (known as Casal's necklace) Lips[web.archive.org] Deficiencies of folates (or folic acid), vitamin B 12 and protein may also cause anaemia.[fao.org]

  • Crohn's Disease

    […] with trouble moving or straightening the arms, hands, legs, or feet; pain deep in the hip bones or ribs; and muscle weakness.[emedicine.com] Complications Because Crohn's disease can cause inflammation in parts of the intestines that absorb nutrients from food, it can cause deficiencies in vitamin B12, folic acid[healthlinkbc.ca] […] include iron and micronutrients (eg, folic acid, vitamin B-12, serum iron, total iron binding capacity, calcium, and magnesium) Stool studies should be obtained to rule out[emedicine.com]

  • Pernicious Anemia

    BACKGROUND/PURPOSE: Macrocytosis is defined as having the mean corpuscular volume (MCV) 100 fL.[ncbi.nlm.nih.gov] […] re standing) A burning feeling in your legs or feet.[webmd.com] Folic Acid Deficiency Anemia Folic acid deficiency is usually due to inadequate amounts of the vitamin in the diet .[revivelifelab.com]

  • Megaloblastic Anaemia in Pregnancy

    Abstract: The occurrence and severity of folic acid deficiency during pregnancy was studied by a folic acid absorption test and measurement of serum folic acid in over 250[popline.org] […] in hands and feet, loss of sensation (e.g. feeling like wearing thin stocking or glove) Unsteady gait and loss of balance: occur in subacute combined spinal cord degeneration[pathologyoutlines.com] Nonalcoholic liver disease and hypothyroidism account for a substantial portion of macrocytosis.[aafp.org]

  • Vitamin Deficiency

    Vitamin B 12 deficiency and folate (folic acid) deficiency cause megaloblastic anemia.[msdmanuals.com] The syndrome of burning feet (nutritional melalgia) as a manifestation of nutritional deficiency.[ods.od.nih.gov] […] erythropoiesis (formation of erythrocytes), it is important for pharmacists to note that microcytosis (low mean corpuscle volume: [MCV]) should suggest sideroblastic anemia, while macrocytosis[uspharmacist.com]

  • Transcobalamin II Deficiency

    Macrocytosis for example is not specific to a vitamin B deficiency in children and also anaemia is not always present – as was previously assumed.[stichtingb12tekort.nl] In other words, excess folate (including folic acid) is more likely to lead to a burning, tingling or numbness in the hands and feets of older adults who happen to be rs1801198[snpedia.com] […] of folinic acid.[ncbi.nlm.nih.gov]

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