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174 Possible Causes for Burning Sensation, Skin Discoloration, Systemic Scleroderma

  • Systemic Scleroderma

    Patients diagnosed with systemic scleroderma can be categorized under two wide categories: diffuse systemic sclerosis (dSSc) and limited cutaneous systemic sclerosis (lSSc[] Patients will present with fatigue, arthralgia, myalgia, pain, and skin discoloration.[] As the disease progresses, the facial skin often tightens into a shiny mask. Swelling may occur, along with skin discoloration, numbness, and a tingling feeling.[]

  • Raynaud Phenomenon

    Raynaud phenomenon (RP) and associated digital ischemia can be among the most vexing clinical problems for patients with systemic sclerosis (scleroderma).[] There may be tingling or burning sensations in the affected area, however, it is usually painless with a feeling of numbness.[] Both primary and secondary RP cause skin discoloration in the digits, which first turn pale and white.[]

  • Raynaud's Disease

    Robert Riggs, CEO of the Scleroderma Foundation ( ), notes that more than 90 percent of people diagnosed with systemic scleroderma also have Raynaud's.[] The pain was intensified by the burning sensation. Raynaud’s disease may develop on its own. In these instances, the reason for the disease is not understood.[] Painful swelling and tingling often accompany skin discoloration episodes.[]

  • Varicose Veins

    Burning sensation over legs/prickly feeling People have trouble describing this, but relate a heat or burning feeling or feeling of “creepy crawlers” underneath the skin of[] While 3 patients (13.6%) noted skin discoloration overlying the treated VVs, none complained of pain on follow-up or developed leg numbness, deep vein thrombosis, or pulmonary[] Commonly, patients will present with chronic sequelae such as itching, discomfort and heaviness of the legs, night cramps, oedema, burning sensations, paraesthesiae, exercise[]

  • Morphea

    sensation, itching, or skin atrophy, were observed in Related Articles Cortexolone 17α-propionate (Clascoterone) Is a Novel Androgen Receptor Anta....[] […] primary biliary cirrhosis , systemic scleroderma , and toxoplasma gondii infection .[] Overview Morphea (mor-FEE-uh) is a rare skin condition that causes painless, discolored patches on your skin.[]

  • Vein Disorder

    Other symptoms may include: Leg pain Fatigue Heaviness Swelling Cramping Tingling, itching or burning sensation Changes in skin color (darkening) Restlessness[] You may experience redness of the legs and ankles, skin discoloration around the ankles or lower legs, or varicose veins which are large, tortuous, and usually grotesquely[] […] a cramping sensation.[]

  • Dyspepsia

    Common signs and symptoms include: A burning sensation or discomfort in your upper abdomen or lower chest Bloating Belching An early feeling of fullness when eating Nausea[] As the condition progresses, jaundice (yellow discoloration of skin and eyes) may be evident , fever and pain accompanied by nausea and vomiting.[] Symptoms included: burning sensation in the throat or chest (sometimes described as chest pain), nausea or a foul taste in the mouth, perspiration . Captain James T.[]

  • Knee Disorder

    An ache or burning sensation at the side of the knee during activity.[] These symptoms typically occur with sweating, warmth, flushing, discoloration, and shiny skin.[]

  • Diabetic Peripheral Neuropathy

    Capsaicin treatment was well tolerated and the most frequent treatment-emergent adverse events were application site pain (30 min, 28.2%; 60 min, 29.3%), burning sensation[] , including dry skin, hair loss, and thick or discolored nails Loss of the ability to sense movement of your joints (proprioception) Drop in blood pressure when you stand[] Diabetic peripheral neuropathy is the most common, and is associated with tingling and burning sensations in the extremities.[]

  • Peripheral Neuropathy

    Other less common causes include exposure to cold or radiation, a few medicines, toxic substances, vascular or collagen disorders, systemic lupus erythematosus, scleroderma[] sensation on the feet that resolved after antituberculosis therapy.[] You are looking for discoloration such as bluish purple spots, redness, sores, cracks in the skin, fungus on the toenails (not uncommon in immune compromised cancer patients[]

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