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74 Possible Causes for Burr Cell, Disseminated Intravascular Coagulation

  • Hemolytic Uremic Syndrome

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] The microthrombi do not include red blood cells (RBCs) or fibrin (unlike thrombi in disseminated intravascular coagulation) and do not manifest the vessel wall granulocytic[merckmanuals.com] Title Other Names: HUS; Acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia associated with distorted erythrocytes ('burr cells') Categories: Hemolytic[rarediseases.info.nih.gov]

  • Microangiopathic Hemolytic Anemia

    - schistocytes, “burr cells”, “helmet cells” and “triangle cells”. 6.[slideshare.net] The possible pathogenesis of MHA and disseminated intravascular coagulation in patients with gastric adenocarcinoma is discussed.[ncbi.nlm.nih.gov] We report a case of insulin-dependent diabetes mellitus in whom microangiopathic hemolytic anemia and chronic disseminated intravascular coagulation (DIC) were thought to[ncbi.nlm.nih.gov]

  • HELLP Syndrome

    Burr cells Schistocytes Reticulocyte count – consider to evaluate for presence of hemolysis Liver enzymes AST – 2 times the upper reference limit meets criteria LDH – markedly[arupconsult.com] Abstract The rate of disseminated intravascular coagulation (DIC) during pregnancy varies among nations from 0.03% to 0.35%.[ncbi.nlm.nih.gov] Abruptio placentae was strongly correlated with the development of disseminated intravascular coagulation (p 0.0001), acute renal failure (p 0.001), and pulmonary edema (p[ncbi.nlm.nih.gov]

  • Preeclampsia

    […] hemodilution of pregnancy Peripheral smear (schistocytes, burr cells, echinocytes) Increased bilirubin ( 1.2 mg/dL) Thrombocytopenia ( 100,000) due to hemolysis and low platelet[emedicine.com] intravascular coagulation (DIC) affecting liver, kidney, brain, heart and placenta due to thrombosis of arterioles and capillaries Etiology Early onset disease is attributed[pathologyoutlines.com] Alternatively, values that are three standard deviations away from the mean for each laboratory value may be used for AST. [45] Histology The presence of schistocytes, burr[emedicine.com]

  • Kasabach Merritt Syndrome

    The laboratory personnel should look for Burr cells and schistocytes.[symptoma.com] […] agents including taxane and doxorubicin could relieve disseminated intravascular coagulation.[ijdvl.com] An uncommon clinical presentation of an angiosarcoma is spontaneous bleeding due to disseminated intravascular coagulation (DIC) by consumption coagulopathy, known as the[ncbi.nlm.nih.gov]

  • Anemia

    Burr cells accompany renal failure and spur cells accompany severe liver disease.[cancertherapyadvisor.com] intravascular coagulation (DIC), cold agglutinin disease, and paroxysmal cold hemoglobinuria (PCH).[emedicine.com] Acute anemia due to disseminated intravascular coagulation Management of disseminated intravascular coagulation (DIC) focuses on treatment of the underlying disorder.[emedicine.com]

  • Congenital Heinz Body Hemolytic Anemia

    Burr Cells: Liver disease Renal disease Severe burns Bleeding gastric ulcers Maybe artifact Echinocyte (Burr Cell) Acanthocyte vs Echinocyte Howell-Jelly: are intracellular[medical-labs.net] Presence of fragmented cells may be due to: Artificial heart valve Disorder in which the proteins that control blood clotting become overactive ( disseminated intravascular[m.ufhealth.org] intravascular coagulation renal graft rejection COPD Acanthocytes resemble spurs on cowboy boots, but they have uneven projections (spicules) Acanthocytes are the rbc's seen[hematologylearning.weebly.com]

  • Eclampsia

    […] hemodilution of pregnancy Peripheral smear (schistocytes, burr cells, echinocytes) Increased bilirubin ( 1.2 mg/dL) Thrombocytopenia ( 100,000) due to hemolysis and low platelet[emedicine.com] Eclampsia with a generalized seizure occurred 5 hours after the cesarean section, while the patient was receiving medical treatment for disseminated intravascular coagulation[ncbi.nlm.nih.gov] […] screen for diagnosis of disseminated intravascular coagulation.[ncbi.nlm.nih.gov]

  • Cerebral Thrombotic Thrombocytopenic Purpura

    cells, helmet-shaped RBCs, normoblasts, reticulocytosis, unconjugated BR, Hb, hemosiderin, haptoglobin, proteinuria Management Corticosteroids, aspirin, dipyridamole, Igs[medical-dictionary.thefreedictionary.com] intravascular coagulation (DIC) (fibrinogen level, 1.25 g/L [125 mg/dL];[jamanetwork.com] […] hemolytic anemia Often severe with Hb 7-9g/dl; severity not related to other organ system dysfunction Negative Coombs' test Smear shows signs of microangiopahy: helmet & burr[faculty.washington.edu]

  • Pregnancy-induced Hypertension

    Burr cells, schistocytes on PBS bilirubin 1.2mg/dl absent plasma haptoglobin2) Elevated liver enzymes AST 72 IU/L LDH 600 IU/L3)Low platelets 1 lakh/mm3 47.[slideshare.net] A 40-year-old woman had pregnancy-induced hypertension, disseminated intravascular coagulation (DIC), choroidal infarction, and magnetic resonance imaging (MRI) high-signal[ncbi.nlm.nih.gov] In general, the accepted values are as follows: Hematologic changes: Abnormal peripheral blood smear (schistocytes, burr cells, or echinocytes) Indirect bilirubin 1.2 mg/dL[clinicaladvisor.com]

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