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16 Possible Causes for Burr Cell, Fainting Spells

  • Folate-Deficiency Anemia

    Folate-deficiency anemia frequently appears in women of childbearing age, in those who are pregnant or lactating, in alcohol abusers and malnourished individuals, thus proving the necessity of folate oral supplementation. Prevention must be carefully conducted, since the elderly may have difficulties tolerating folate[…][]

  • Anemia

    Burr cells accompany renal failure and spur cells accompany severe liver disease.[] Elliptocytes or bizarre misshapen cells indicate inherited membrane disorders like elliptocytosis, pyropoikilocytosis, ovalocytosis, tomatocytosis, xerocytosis.[] Target cells coupled with macrocytosis suggests liver disease, normocytic target cells raise the suspicion of hemoglobin C or SC disease, while microcytosis with target cells[]

  • Abetalipoproteinemia

    (burr cells) due to lipid membrane abnormalities Microscopic (histologic) description Marked fat vacuoles in apical villous cytoplasm, normal villi Positive stains Fat stains[] […] that may be done to help diagnose this condition include: Apolipoprotein B blood test Blood tests to look for vitamin deficiencies (fat-soluble vitamins A, D, E, and K) "Burr-cell[] […] apoprotein B from intestinal mucosal cells As a result, free fatty acids and monoglycerides cannot be assembled into chylomicrons and become triglycerides stored within cells[]

  • Cor Pulmonale

    A peripheral blood smear revealed burr cells and schistocytes, suggesting microangiopathic hemolytic anemia (MAHA).[] Symptoms you may have are: Fainting spells during activity Chest discomfort, usually in the front of the chest Chest pain Swelling of the feet or ankles Symptoms of lung disorders[] As the disease worsens, the following symptoms may occur with lighter activity, or even while you’re resting: 4 Fainting spells with activity Chest discomfort and/or chest[]

  • Uremia

    Some cases of uremia have also been associated with abnormal red blood cells, such as echinocytes, which are often better known as burr cells.[]

  • Posthemorrhagic Anaemia of the Newborn

    Other findings include burr cells (uremia), spherocytes (hereditary spherocytosis, autoimmune hemolysis, G6PD deficiency), elliptocytes (hereditary elliptocytosis), schistocytes[] , which may suggest the presence of mixed microcytic and macrocytic disease processes (a finding that should be suggested by an elevated red blood cell distribution width)[] […] reticulocytosis; target cells, which may be found in liver disease; basophilic stippling, which may be present in hemolytic anemias; and mixtures of large and small red blood cells[]

  • Catecholaminergic Polymorphic Ventricular Tachycardia Type 2

    J Mol Cell Cardiol. 2010 ; 48 :1329–1334. doi: 10.1016/j.yjmcc.2010.01.020. Crossref Medline Google Scholar 180.[] Correll RN, Goonasekera SA, van Berlo JH, Burr AR, Accornero F, Zhang H, Makarewich CA, York AJ, Sargent MA, Chen X, Houser SR, Molkentin JD.[]

  • Normocytic Normochromic Anemia

    cells Chronic renal failure Spherocytes, fragments Hemolytic diseases Dysplastic changes Myelodysplasia Reticulocyte count 1% Inadequate production in presence of anemia[] […] folate deficiency MCV normal Renal, liver and thyroid diseases as well as those above WBC and platelet counts Abnormal Primary marrow production problem Peripheral smear Burr[]

  • Acquired Thrombotic Thrombocytopenic Purpura

    cells, helmet-shaped RBCs, normoblasts, reticulocytosis, unconjugated BR, Hb, hemosiderin, haptoglobin, proteinuria Management Corticosteroids, aspirin, dipyridamole, Igs[] […] coagulation factors, complement proteins, Coombs-negative microangiopathic hemolytic anemia–often severe, 30% have Hb 55g/L, US: 5.5 g/dl and reticulocytosis, schistocytes, burr[]

  • Eclampsia

    […] hemodilution of pregnancy Peripheral smear (schistocytes, burr cells, echinocytes) Increased bilirubin ( 1.2 mg/dL) Thrombocytopenia ( 100,000) due to hemolysis and low platelet[] Hematologic Studies A complete blood cell (CBC) count may reveal the following: Anemia due to microangiopathic hemolysis, hemoconcentration due to third spacing, or physiologic[]

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