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35 Possible Causes for Burr Cell, Haptoglobin Decreased

  • Hemolytic Uremic Syndrome

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] […] hemolysis, which is characterized by elevated LDH levels, decreased haptoglobin, decreased hemoglobin, and/or the presence of schistocytes.[en.wikipedia.org] Title Other Names: HUS; Acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia associated with distorted erythrocytes ('burr cells') Categories: Hemolytic[rarediseases.info.nih.gov]

  • Microangiopathic Hemolytic Anemia

    - schistocytes, “burr cells”, “helmet cells” and “triangle cells”. 6.[slideshare.net] He was diagnosed with MAHA on the basis of the laboratory findings that revealed anemia with schistocytes, decreased haptoglobin levels, and a negative direct Coombs' test[ncbi.nlm.nih.gov] -schistocytes -fragements -burr cells -microspherocytes What are some causes of microangiopathic hemolytic anemia?[quizlet.com]

  • Folate-Deficiency Anemia

    Folate-deficiency anemia frequently appears in women of childbearing age, in those who are pregnant or lactating, in alcohol abusers and malnourished individuals, thus proving the necessity of folate oral supplementation. Prevention must be carefully conducted, since the elderly may have difficulties tolerating folate[…][symptoma.com]

  • Abetalipoproteinemia

    (burr cells) due to lipid membrane abnormalities Microscopic (histologic) description Marked fat vacuoles in apical villous cytoplasm, normal villi Positive stains Fat stains[pathologyoutlines.com] […] that may be done to help diagnose this condition include: Apolipoprotein B blood test Blood tests to look for vitamin deficiencies (fat-soluble vitamins A, D, E, and K) "Burr-cell[health.ridgeviewmedical.org] […] apoprotein B from intestinal mucosal cells As a result, free fatty acids and monoglycerides cannot be assembled into chylomicrons and become triglycerides stored within cells[pathologyoutlines.com]

  • Atypical Hemolytic Uremic Syndrome

    A peripheral blood smear (PBS) was performed, which contained schistocytes (32%) with helmet and burr cells.[ncbi.nlm.nih.gov] […] hemolysis, which is characterized by elevated LDH levels, decreased haptoglobin, decreased hemoglobin, and/or the presence of schistocytes.[en.wikipedia.org] After 3 years of eculizumab treatment, and without plasma therapy, schistocytes decreased, haptoglobin increased to within normal limits, creatinine levels stabilized, and[ncbi.nlm.nih.gov]

  • Congenital Heinz Body Hemolytic Anemia

    Burr Cells: Liver disease Renal disease Severe burns Bleeding gastric ulcers Maybe artifact Echinocyte (Burr Cell) Acanthocyte vs Echinocyte Howell-Jelly: are intracellular[medical-labs.net] Intravascular hemolysis is suggested by RBC fragments (schistocytes) on the peripheral smear and by decreased serum haptoglobin levels; however, haptoglobin levels can decrease[merckmanuals.com] Haptoglobin (intravascular haemolysis) Urine Haemoglobin Haemosiderin (useful in the diagnosis of intravascular haemolysis) Identify cause (history peripheral blood film[lifeinthefastlane.com]

  • HELLP Syndrome

    Burr cells Schistocytes Reticulocyte count – consider to evaluate for presence of hemolysis Liver enzymes AST – 2 times the upper reference limit meets criteria LDH – markedly[arupconsult.com] […] from baseline of at least 25%) [15] and evidence of microangiopathic hemolysis, which is characterized by elevated LDH levels, decreased haptoglobin, decreased hemoglobin[en.wikipedia.org] Laboratory studies should include: Complete blood cell (CBC) count Coagulation studies Peripheral smear for schistocytes, helmet cells, burr cells Liver function tests: serum[symptoma.com]

  • Uremic Pneumonitis

    Diagnosis Peripheral blood smear establishes the presence of MAHA by schistocytes, burr cells, helmet cells etc.[omicsonline.org] haptoglobin with no signs of autoimmunity), thrombocytopenia and acute kidney injury as evidenced by elevation of serum creatinine above the upper limit for age.[karger.com] They fulfilled the criteria for HUS [hemolytic anemia with microangiopathic changes on peripheral blood smear (Burr cells), acute renal failure, and thrombocytopenia] and[clinchem.aaccjnls.org]

  • Acquired Spherocytosis

    Crenated / Burr cells / Echinocytes (Echinocytes, or burr cells or crenated red cells, in contrast, have shorter, sharp to blunt spicules of uniform length which are more[slideshare.net] Intravascular hemolysis is suggested by RBC fragments (schistocytes) on the peripheral smear and by decreased serum haptoglobin levels; however, haptoglobin levels can decrease[msdmanuals.com] -thus, if Hemolysis is occuring, free Haptoglobin will be DECREASED on Lab Results Laboratory Features of Hemolysis (2 Factors) -Signs of RBC Destruction -Signs of Accelerated[quizlet.com]

  • Leukoerythroblastic Anemia

    cells (echinocytes) may indicate: Uremia The presence of spur cells (acanthocytes) may indicate: Abetalipoproteinemia Severe liver disease The presence of teardrop-shaped[ucsfbenioffchildrens.org] […] serum haptoglobin in both intravascular and extravascular • intracorpuscular and extracorpuscular Hemolytic Anemia Diagram ![quizlet.com] They may be artefactual - see Crenated cells - or pathological - see Burr cells above.[patient.info]

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