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40 Possible Causes for Burr Cell, HELLP Syndrome

  • Hemolytic Uremic Syndrome

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] A pregnancy complicated by typical hemolytic uremic syndrome (HUS) and hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome is reported.[ncbi.nlm.nih.gov] Title Other Names: HUS; Acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia associated with distorted erythrocytes ('burr cells') Categories: Hemolytic[rarediseases.info.nih.gov]

  • Microangiopathic Hemolytic Anemia

    - schistocytes, “burr cells”, “helmet cells” and “triangle cells”. 6.[slideshare.net] The syndrome of hemolytic anemia, elevated liver enzymes and low platelets (HELLP) can accompany preeclampsia and eclampsia.[ncbi.nlm.nih.gov] -schistocytes -fragements -burr cells -microspherocytes What are some causes of microangiopathic hemolytic anemia?[quizlet.com]

  • HELLP Syndrome

    Burr cells Schistocytes Reticulocyte count – consider to evaluate for presence of hemolysis Liver enzymes AST – 2 times the upper reference limit meets criteria LDH – markedly[arupconsult.com] How is HELLP syndrome diagnosed?There is no specific diagnostic testing for HELLP syndrome.[symptoma.com] The classic findings of microangiopathic hemolysis include abnormal peripheral smear (schistocytes, burr cells, echinocytes), elevated serum bilirubin (indirect form), low[womenshealthsection.com]

  • Preeclampsia

    […] hemodilution of pregnancy Peripheral smear (schistocytes, burr cells, echinocytes) Increased bilirubin ( 1.2 mg/dL) Thrombocytopenia ( 100,000) due to hemolysis and low platelet[emedicine.com] Severe preeclampsia with hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome is a leading cause of maternal and neonatal morbidity and mortality worldwide[ncbi.nlm.nih.gov] Alternatively, values that are three standard deviations away from the mean for each laboratory value may be used for AST. [45] Histology The presence of schistocytes, burr[emedicine.com]

  • Pregnancy-induced Hypertension

    Burr cells, schistocytes on PBS bilirubin 1.2mg/dl absent plasma haptoglobin2) Elevated liver enzymes AST 72 IU/L LDH 600 IU/L3)Low platelets 1 lakh/mm3 47.[slideshare.net] Pregnancies complicated by HELLP syndrome are associated with poor maternal and fetal outcome.[ncbi.nlm.nih.gov] In general, the accepted values are as follows: Hematologic changes: Abnormal peripheral blood smear (schistocytes, burr cells, or echinocytes) Indirect bilirubin 1.2 mg/dL[clinicaladvisor.com]

  • Hepatic Rupture

    It is characterized by microangiopathic hemolysis with burr cells and schistocytes on peripheral smear; elevated liver enzyme levels, with aspartate transaminase (AST) exceeding[clevelandclinicmeded.com] A retrospective study of HELLP syndrome cases that were complicated by hepatic rupture was conducted. Ten cases of hepatic rupture were identified.[ncbi.nlm.nih.gov] This report describes 3 cases of extensive spontaneous hepatic rupture in pregnant women with HELLP syndrome.[ncbi.nlm.nih.gov]

  • Eclampsia

    […] hemodilution of pregnancy Peripheral smear (schistocytes, burr cells, echinocytes) Increased bilirubin ( 1.2 mg/dL) Thrombocytopenia ( 100,000) due to hemolysis and low platelet[emedicine.com] Back to top What is HELLP syndrome? HELLP syndrome is one of the most severe forms of preeclampsia and occurs in 5-12% of preeclamptic patients.[preeclampsia.org] syndrome.[ncbi.nlm.nih.gov]

  • Recurrent Jaundice of Pregnancy

    It is characterized by microangiopathic hemolysis with burr cells and schistocytes on peripheral smear; elevated liver enzyme levels, with aspartate transaminase (AST) exceeding[clevelandclinicmeded.com] PREECLAMPSIA/ECLAMPSIA AND HELLP SYNDROME Preeclampsia is a syndrome that is unique to pregnancy.[wjgnet.com] HELLPSYNDROME • Hemolysis, Elevated Liver enzymes,and Low Platelet count (HELLP) syndrome . • Multi-system disease variant of severe preeclampsia that is characterized[slideshare.net]

  • Atypical Hemolytic Uremic Syndrome

    A peripheral blood smear (PBS) was performed, which contained schistocytes (32%) with helmet and burr cells.[ncbi.nlm.nih.gov] We found that HELLP syndrome is associated with increased complement activation as assessed with the modified Ham test.[ncbi.nlm.nih.gov] […] with an MCP mutation and the HELLP syndrome.[doi.org]

  • Anemia

    Burr cells accompany renal failure and spur cells accompany severe liver disease.[cancertherapyadvisor.com] , an autoimmune disorder HELLP syndrome (named for its characteristics, which include hemolysis, elevated liver enzymes, and low platelet count) Hemolytic anemia isn’t always[healthline.com] Elliptocytes or bizarre misshapen cells indicate inherited membrane disorders like elliptocytosis, pyropoikilocytosis, ovalocytosis, tomatocytosis, xerocytosis.[cancertherapyadvisor.com]

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