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40 Possible Causes for Burr Cell, Hematocrit Decreased, Thrombotic Thrombocytopenic Purpura

  • Microangiopathic Hemolytic Anemia

    - schistocytes, “burr cells”, “helmet cells” and “triangle cells”. 6.[slideshare.net] The similarity of the mother's illness to thrombotic thrombocytopenic purpura and of the daughter's to adult hemolytic uremic syndrome suggests that these diseases are variants[ncbi.nlm.nih.gov] Our understanding of the pathogenesis of idiopathic thrombotic thrombocytopenic purpura (TTP) has increased, but remains incomplete, particularly with respect to cases of[ncbi.nlm.nih.gov]

  • HELLP Syndrome

    Burr cells Schistocytes Reticulocyte count – consider to evaluate for presence of hemolysis Liver enzymes AST – 2 times the upper reference limit meets criteria LDH – markedly[arupconsult.com] The laboratory investigations before death revealed evidence of hemolysis, which is decreased hematocrit, elevated lactate dehydrogenase (865 U/L), and low platelet count[ncbi.nlm.nih.gov] CONCLUSION: Thrombotic thrombocytopenic purpura can mimic HELLP syndrome late in gestation.[ncbi.nlm.nih.gov]

  • Anemia

    Burr cells accompany renal failure and spur cells accompany severe liver disease.[cancertherapyadvisor.com] Throughout fetal life, erythrocytes decrease in size and increase in number: hematocrit increases from 30% to 40% during the second trimester to 50% to 63% at term.[pedsinreview.aappublications.org] Hemolytic anemia This type of anemia includes sickle cell anemia, thrombotic thrombocytopenic purpura (TTP), hemolytic uremic syndrome, aortic valve prosthesis, disseminated[emedicine.com]

  • Hemolytic Uremic Syndrome

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] Hemoglobin at the time of MRI (n 35) was decreased in all patients (range, 5.0 to 12.6 g/dL; mean, 8.2 1.4); hematocrit (n 33) was abnormally low in all but a single patient[ncbi.nlm.nih.gov] Thrombotic thrombocytopenic purpura associated with ticlopidine-Thrombotic Thrombocytopenic Purpura (TTP) 271 a review of 60 cases. Ann Intern Med 1998;128: 541–544.[doi.org]

  • Cerebral Thrombotic Thrombocytopenic Purpura

    cells, helmet-shaped RBCs, normoblasts, reticulocytosis, unconjugated BR, Hb, hemosiderin, haptoglobin, proteinuria Management Corticosteroids, aspirin, dipyridamole, Igs[medical-dictionary.thefreedictionary.com] He also had melena with rapid decline in hematocrit and was treated with single dose of IVIg 75 g.[ijccm.org] KEYWORDS: Cerebral microbleeds; MRI; ischemic stroke; thrombotic thrombocytopenic purpura[ncbi.nlm.nih.gov]

  • Atypical Hemolytic Uremic Syndrome

    A peripheral blood smear (PBS) was performed, which contained schistocytes (32%) with helmet and burr cells.[ncbi.nlm.nih.gov] hematocrit and hemoglobin and thrombocytopenia ; schistocytes on peripheral blood smears, elevated LDH, low haptoglobin, elevated indirect bilirrubin, elevated reticulocytes[biomed.uninet.edu] Thrombotic thrombocytopenic purpura (TTP) and atypical hemolytic uremic syndrome (aHUS) are thrombotic microangiopathies (TMAs) that can present in pregnancy.[ncbi.nlm.nih.gov]

  • Anemia of Chronic Disease

    cells Chronic renal failure Spherocytes, fragments Hemolytic diseases Dysplastic changes Myelodysplasia Reticulocyte count 1% Inadequate production in presence of anemia[aafp.org] Management Transient decrease in hemoglobin and hematocrit are common in the early phases of the MP. My use of lab tests is to help determine pace of therapy.[mpkb.org] Severe red cell fragmentation Microangiopathic hemolytic anemias: Malfunctioning mechanical heart valve, disseminated intravascular coagulation, thrombotic thrombocytopenic[quizlet.com]

  • Carcinoma of the Prostate

    Evident re-accumulation of the previously drained left sided subdural collection with frontal and parietal burr-holes causing mass effect.[surgicalneurologyint.com] Full Text Introduction Thrombotic microangiopathy is a broad term that encompasses a range of conditions from immune-mediated thrombotic thrombocytopenic purpura (TTP) to[htct.com.br] microangiopathy, NBTE and massive thromboembolism.[jpma.org.pk]

  • Uremic Anemia

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] Cardiac index decreased during transfusion, reaching a normal level at a hematocrit of 30%.[ahajournals.org] Thrombotic thrombocytopenic purpura (similar to hemolytic-uremic syndrome ) involves nonimmunologic platelet destruction.[merckmanuals.com]

  • Acquired Spherocytosis

    Crenated / Burr cells / Echinocytes (Echinocytes, or burr cells or crenated red cells, in contrast, have shorter, sharp to blunt spicules of uniform length which are more[slideshare.net] A complete blood count (CBC) may show increased reticulocytes, a sign of increased red blood cell production, and decreased hemoglobin and hematocrit.[en.wikipedia.org] Red cell morphology: eg, haemolytic uraemic syndrome, thrombotic thrombocytopenic purpura.[patient.info]

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