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45 Possible Causes for Burr Cell, Lactate Decreased

  • Folate-Deficiency Anemia

    […] hepatic levels of dihydrofolate reductase) Congenital deficiency of enzymes of folate metabolism Increased requirement: infancy, pregnancy, lactation, malignancy, concurrent[pathologyoutlines.com] […] strictures, jejunal diverticula Impaired metabolism, leading to inability to utilize absorbed folate: methotrexate and trimethoprim (folate antagonists) Hypothyroidism (decreases[pathologyoutlines.com]

  • Preeclampsia

    […] hemodilution of pregnancy Peripheral smear (schistocytes, burr cells, echinocytes) Increased bilirubin ( 1.2 mg/dL) Thrombocytopenia ( 100,000) due to hemolysis and low platelet[emedicine.com] In this situation, the patient should be hydrated with an infusion of 1,000 mL lactated ringer or saline before sympathetic block to avoid severe hypotension with decreased[scielo.br] Alternatively, values that are three standard deviations away from the mean for each laboratory value may be used for AST. [45] Histology The presence of schistocytes, burr[emedicine.com]

  • Hemolytic Uremic Syndrome

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] Following an increase in the dose of eculizumab to 1,500 mg every 2 weeks, lactate dehydrogenase (LDH), proteinuria, and creatinine decreased, and CH50 assay showed 0%.[ncbi.nlm.nih.gov] Title Other Names: HUS; Acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia associated with distorted erythrocytes ('burr cells') Categories: Hemolytic[rarediseases.info.nih.gov]

  • Microangiopathic Hemolytic Anemia

    - schistocytes, “burr cells”, “helmet cells” and “triangle cells”. 6.[slideshare.net] The diagnosis is established by reticulocytosis, increased unconjugated bilirubin and lactate dehydrogenase, decreased haptoglobin, and peripheral blood smear findings.[aafp.org] -schistocytes -fragements -burr cells -microspherocytes What are some causes of microangiopathic hemolytic anemia?[quizlet.com]

  • Anemia

    Burr cells accompany renal failure and spur cells accompany severe liver disease.[cancertherapyadvisor.com] Increasing platelet count, decreasing lactate dehydrogenase (LDH), and decreasing red blood cell (RBC) fragments indicate a positive response to treatment.[emedicine.com] Elliptocytes or bizarre misshapen cells indicate inherited membrane disorders like elliptocytosis, pyropoikilocytosis, ovalocytosis, tomatocytosis, xerocytosis.[cancertherapyadvisor.com]

  • Congenital Heinz Body Hemolytic Anemia

    Burr Cells: Liver disease Renal disease Severe burns Bleeding gastric ulcers Maybe artifact Echinocyte (Burr Cell) Acanthocyte vs Echinocyte Howell-Jelly: are intracellular[medical-labs.net] Bilirubin (total and direct) and lactate acid dehydrogenase (LDH) should also be obtained.[oncologynurseadvisor.com] Spur cell is seen in severe liver diseases Burr cell These are irregularly contracted red cells. These are seen in : Renal diseases. Fragmented cells are seen in : DIC.[labpedia.net]

  • HELLP Syndrome

    Burr cells Schistocytes Reticulocyte count – consider to evaluate for presence of hemolysis Liver enzymes AST – 2 times the upper reference limit meets criteria LDH – markedly[arupconsult.com] The laboratory investigations before death revealed evidence of hemolysis, which is decreased hematocrit, elevated lactate dehydrogenase (865 U/L), and low platelet count[ncbi.nlm.nih.gov] Conversely, lactate dehydrogenase concentrations usually peaked 24 to 48 hours post partum.[ncbi.nlm.nih.gov]

  • Leukoerythroblastic Anemia

    cells (echinocytes) may indicate: Uremia The presence of spur cells (acanthocytes) may indicate: Abetalipoproteinemia Severe liver disease The presence of teardrop-shaped[ucsfbenioffchildrens.org] […] the bone marrow makes too many red blood cells): 2 people, 28.57% Bone Marrow Reticulin Fibrosis (thickening and scarring of bone marrow reticulin): 2 people, 28.57% Blood Lactate[ehealthme.com] They may be artefactual - see Crenated cells - or pathological - see Burr cells above.[patient.info]

  • Acquired Spherocytosis

    Crenated / Burr cells / Echinocytes (Echinocytes, or burr cells or crenated red cells, in contrast, have shorter, sharp to blunt spicules of uniform length which are more[slideshare.net] The diagnosis is established by reticulocytosis, increased unconjugated bilirubin and lactate dehydrogenase, decreased haptoglobin, and peripheral blood smear findings.[aafp.org] Burr cells (echinocytes): can indicate uremia or pyruvate kinase-deficient states. Burr cells are commonly observed as an artifact of peripheral smear preparation.[cancertherapyadvisor.com]

  • Waisman Syndrome

    The peripheral smear may reveal spherocytes, schistocytes, triangular cells and burr cells.[aafp.org] In these patients, plasmapheresis has resulted in an increase in the platelet count and a decrease in the lactate dehydrogenase level. 23 – 25 ANESTHESIA CONSIDERATIONS Pain[aafp.org] Red blood cells become fragmented as they pass through small blood vessels with endothelial damage and fibrin deposits.[aafp.org]

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