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49 Possible Causes for Burr Cell, Malignant Hypertension

  • Hemolytic Uremic Syndrome

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] hypertension, drugs (mitomycin C, cyclosporine, bleomycin, cisplatin) and various malignancies Lupus patients may have more severe disease ( Am J Med Sci 2009;338:343 , Nephron[pathologyoutlines.com] Title Other Names: HUS; Acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia associated with distorted erythrocytes ('burr cells') Categories: Hemolytic[rarediseases.info.nih.gov]

  • Microangiopathic Hemolytic Anemia

    - schistocytes, “burr cells”, “helmet cells” and “triangle cells”. 6.[slideshare.net] The fourth case found in Japan manifesting the features of malignant hypertension and microangiopathic hemolytic anemia (MHA) was reported.[ncbi.nlm.nih.gov] 抄録 The fourth case found in Japan manifesting the features of malignant hypertension and microangiopathic hemolytic anemia (MHA) was reported.[jstage.jst.go.jp]

  • Preeclampsia

    […] hemodilution of pregnancy Peripheral smear (schistocytes, burr cells, echinocytes) Increased bilirubin ( 1.2 mg/dL) Thrombocytopenia ( 100,000) due to hemolysis and low platelet[emedicine.com] TMA is a term used to describe a group of clinically diverse entities, such as hemolytic uremic syndrome and malignant hypertension, among others, that are defined by a primary[jasn.asnjournals.org] […] heart and chronic kidney disease 642.2 hemorrhage 641.9 hepatitis (acute) (malignant) (subacute) 646.7 viral 647.6 herniation of uterus 654.4 high head at term 652.5 hydatidiform[icd9data.com]

  • Anemia

    Burr cells accompany renal failure and spur cells accompany severe liver disease.[cancertherapyadvisor.com] hypertension, and hemolytic-uremic syndrome [HUS]), artificial heart valves, turbulent flow through arterial venous malformations, etc.[cancertherapyadvisor.com] Elliptocytes or bizarre misshapen cells indicate inherited membrane disorders like elliptocytosis, pyropoikilocytosis, ovalocytosis, tomatocytosis, xerocytosis.[cancertherapyadvisor.com]

  • Uremic Anemia

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] Autopsy revealed the stigmata of malignant hypertension with widespread arteriolar necrosis, fragmentation of the arteriolar wall and thrombosis with recent infarcts in the[journals.lww.com] Diagnosis Peripheral blood smear establishes the presence of MAHA by schistocytes, burr cells, helmet cells etc.[omicsonline.org]

  • Acquired Spherocytosis

    Crenated / Burr cells / Echinocytes (Echinocytes, or burr cells or crenated red cells, in contrast, have shorter, sharp to blunt spicules of uniform length which are more[slideshare.net] Common Red Cell Fragmentation Syndromes -Prosthetic heart valves -Thrombotic thrombocytopenic purpura (TTP) -Hemolytic - uremic syndrome (HUS) -Malignant hypertension -Disseminated[quizlet.com] Burr cells (echinocytes): can indicate uremia or pyruvate kinase-deficient states. Burr cells are commonly observed as an artifact of peripheral smear preparation.[cancertherapyadvisor.com]

  • Congenital Heinz Body Hemolytic Anemia

    Burr Cells: Liver disease Renal disease Severe burns Bleeding gastric ulcers Maybe artifact Echinocyte (Burr Cell) Acanthocyte vs Echinocyte Howell-Jelly: are intracellular[medical-labs.net] , malignant hypertension, sisseminated intravascular coagulation (DIC), preeclampsia/ eclampsia Thrombotic microangiopathy (MAHA, thrombosis and thrombocytopenia), e.g.[lifeinthefastlane.com] Spur cell is seen in severe liver diseases Burr cell These are irregularly contracted red cells. These are seen in : Renal diseases. Fragmented cells are seen in : DIC.[labpedia.net]

  • Cerebral Thrombotic Thrombocytopenic Purpura

    cells, helmet-shaped RBCs, normoblasts, reticulocytosis, unconjugated BR, Hb, hemosiderin, haptoglobin, proteinuria Management Corticosteroids, aspirin, dipyridamole, Igs[medical-dictionary.thefreedictionary.com] hypertension, drugs (mitomycin C, cyclosporine, bleomycin, cisplatin) and various malignancies Lupus patients may have more severe disease ( Am J Med Sci 2009;338:343, Nephron[pathologyoutlines.com] […] hemolytic anemia Often severe with Hb 7-9g/dl; severity not related to other organ system dysfunction Negative Coombs' test Smear shows signs of microangiopahy: helmet & burr[faculty.washington.edu]

  • Atypical Hemolytic Uremic Syndrome

    A peripheral blood smear (PBS) was performed, which contained schistocytes (32%) with helmet and burr cells.[ncbi.nlm.nih.gov] In this review, three case reports are presented illustrating the onset and diagnosis of aHUS in the setting of different CACs (pregnancy complications, malignant hypertension[ncbi.nlm.nih.gov] Complementary laboratory study excluded malignant hypertension, autoimmunity diseases, HIV and H1N1 infection.[medintensiva.org]

  • HELLP Syndrome

    Burr cells Schistocytes Reticulocyte count – consider to evaluate for presence of hemolysis Liver enzymes AST – 2 times the upper reference limit meets criteria LDH – markedly[arupconsult.com] , hypertensive (accelerated) (benign) (essential) (idiopathic) (malignant) (systemic) I10 ICD-10-CM Diagnosis Code I10 Essential (primary) hypertension 2016 2017 2018 2019[icd10data.com] Laboratory studies should include: Complete blood cell (CBC) count Coagulation studies Peripheral smear for schistocytes, helmet cells, burr cells Liver function tests: serum[symptoma.com]

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