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30 Possible Causes for Burr Cell, Mean Corpuscular Volume Increased

  • Folate-Deficiency Anemia

    The mean corpuscular volume is typically increased (above 96 fL ).[symptoma.com] Folate Deficiency causes a specific type of Anemia called Macrocytic/Megaloblstic Anemia where the size (Mean Corpuscular Volume) of the red blood cells increased .[stomponstep1.com] In a recent study, 7 percent of patients had a mean corpuscular volume greater than 96 fL, and 1.7 percent had a mean corpuscular volume greater than 100 fL. 2 With the advent[aafp.org]

  • Hemolytic Uremic Syndrome

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] Title Other Names: HUS; Acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia associated with distorted erythrocytes ('burr cells') Categories: Hemolytic[rarediseases.info.nih.gov]

  • Abetalipoproteinemia

    (burr cells) due to lipid membrane abnormalities Microscopic (histologic) description Marked fat vacuoles in apical villous cytoplasm, normal villi Positive stains Fat stains[pathologyoutlines.com] […] that may be done to help diagnose this condition include: Apolipoprotein B blood test Blood tests to look for vitamin deficiencies (fat-soluble vitamins A, D, E, and K) "Burr-cell[health.ridgeviewmedical.org] […] apoprotein B from intestinal mucosal cells As a result, free fatty acids and monoglycerides cannot be assembled into chylomicrons and become triglycerides stored within cells[pathologyoutlines.com]

  • Leukoerythroblastic Anemia

    cells (echinocytes) may indicate: Uremia The presence of spur cells (acanthocytes) may indicate: Abetalipoproteinemia Severe liver disease The presence of teardrop-shaped[ucsfbenioffchildrens.org] mean corpuscular volume (macrocytic anemia: MCV 100 fL) Ethanol abuse Folate deficiency Vitamin B12 deficiency Myelodysplastic syndromes Acute myeloid leukemias (eg, erythroleukemia[timeofcare.com] They may be artefactual - see Crenated cells - or pathological - see Burr cells above.[patient.info]

  • Fetal Erythroblastosis

    Schistocytes, as a sign of disseminated intravascular coagulation and burr cells, are present, as well as neutropenia and thrombocytopenia.[symptoma.com] If there is extensive disseminated intravascular coagulation, schistocytes and burr cells may be observed and neutropenia and thrombocytopenia may occur.[patient.info] He or she will be anemic, with increased reticulocyte count, anisocytosis, spherocytosis, and young (nucleated, immature) red blood cells released into circulation.[symptoma.com]

  • Paroxysmal Cold Hemoglobinuria

    RBC survival may be shortened in renal failure (burr cells) and in liver disease (acanthocytes and target cells).[med-ed.virginia.edu] In cold agglutinin disease, RBCs clump on the peripheral smear, and automated cell counts often reveal an increased mean corpuscular volume and spuriously low hemoglobin due[msdmanuals.com]

  • Anemia

    Burr cells accompany renal failure and spur cells accompany severe liver disease.[cancertherapyadvisor.com] (MCV mean corpuscular volume.) An Hgb increase of more than 1 g per dL (10 g per L) after iron therapy has been started confirms the diagnosis of iron deficiency.[aafp.org] Average size of RBCs (mean corpuscular volume, MCV)—decreased Average amount of hemoglobin in RBCs (mean corpuscular hemoglobin, MCH)—decreased Hemoglobin concentration (mean[labtestsonline.org]

  • Other Sideroblastic Anemias

    Anemia of Chronic Renal Disease blood picture: Usually normocytic/normochromic, decreased Hb, Burr cells Variable blood pictures: N/N with burr cells Macro/N with target cells[quizlet.com] The findings of a mean age at onset of 70 years, increased mean corpuscular volume, relative neutropenia; and occasional splenomegaly at diagnosis corresponded with previous[ncbi.nlm.nih.gov] Even when pyridoxine completely corrects the anemia, the increase in mean corpuscular volume (MCV) may not reach normal values, and a population of hypochromic, microcytic[clinicalgate.com]

  • Acquired Spherocytosis

    Crenated / Burr cells / Echinocytes (Echinocytes, or burr cells or crenated red cells, in contrast, have shorter, sharp to blunt spicules of uniform length which are more[slideshare.net] RBC Hematological Changes during Storage Along with the increasing storage time, the mean corpuscular volume (MCV) maintained a constant upward trend, and it increased significantly[mdpi.com] The RDW can be used, along with the mean corpuscular volume to identify the presence and cause of anemia.[clevelandheartlab.com]

  • Red Blood Cell Disorder

    Burr Cells: Liver disease Renal disease Severe burns Bleeding gastric ulcers Maybe artifact Echinocyte (Burr Cell) Acanthocyte vs Echinocyte Howell-Jelly: are intracellular[medical-labs.net] Mean Corpuscular Hemoglobin Concentration (MCHC) MCHC indicates the amount of hemoglobin per unit volume of the red blood cell (R).[selfhacked.com] The poikilocytes caused by membrane abnormalities are: Acanthocytes (Spur Cells) Codocytes (Target Cells) Echinocytes and Burr Cells Spherocytes Stomatocytes (Mouth Cells)[theartofmed.wordpress.com]

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