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56 Possible Causes for Burr Cell, Pallor, Thrombotic Thrombocytopenic Purpura

  • Hemolytic Uremic Syndrome

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] However, eight days post delivery, the patient developed severe nausea and vomiting followed by hematuria, spontaneous bruising, marked pallor, icteric sclera, and lethargy[ncbi.nlm.nih.gov] Thrombotic thrombocytopenic purpura associated with ticlopidine-Thrombotic Thrombocytopenic Purpura (TTP) 271 a review of 60 cases. Ann Intern Med 1998;128: 541–544.[doi.org]

  • Microangiopathic Hemolytic Anemia

    - schistocytes, “burr cells”, “helmet cells” and “triangle cells”. 6.[slideshare.net] -sudden pallor -black urine then oliguria (low urine output) then anuria How do you diagnose hemolytic uremia syndrome?[quizlet.com] The similarity of the mother's illness to thrombotic thrombocytopenic purpura and of the daughter's to adult hemolytic uremic syndrome suggests that these diseases are variants[ncbi.nlm.nih.gov]

  • Anemia

    Burr cells accompany renal failure and spur cells accompany severe liver disease.[cancertherapyadvisor.com] Pallor has poor sensitivity for predicting mild anemia, but correlates well with severe anemia. 11 – 13 One study showed that physical examination findings of pallor of the[aafp.org] Hemolytic anemia This type of anemia includes sickle cell anemia, thrombotic thrombocytopenic purpura (TTP), hemolytic uremic syndrome, aortic valve prosthesis, disseminated[emedicine.com]

  • Uremic Anemia

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] Excoriations (uremic pruritus), pallor (anemia), muscle wasting, and a nitrogenous fetor are all signs of advanced CKD, as are pericarditis, pleuritis, and asterixis, complications[accessmedicine.mhmedical.com] Thrombotic thrombocytopenic purpura (similar to hemolytic-uremic syndrome ) involves nonimmunologic platelet destruction.[merckmanuals.com]

  • Acquired Immunodeficiency Syndrome

    Pitchenik AE, Burr J, Suarez M, Fertel D, Gonzalez G, Moas C.[cdc.gov] Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome resulting in death has been reported among HIV-1--infected patients treated with high-dose valacyclovir but has[cdc.gov] Human T-cell lymphotropic virus-III (HTLV-III) seropositivity and related disease among 71 consecutive patients in whom tuberculosis was diagnosed: a prospective study.[cdc.gov]

  • Atypical Hemolytic Uremic Syndrome

    A peripheral blood smear (PBS) was performed, which contained schistocytes (32%) with helmet and burr cells.[ncbi.nlm.nih.gov] We present the case of a 2-month-old infant presenting with pallor and laboratory results showing: hemoglobin 5.1 (10 to 1.5) g/dL, MCV 94.7 (75 to 105) fL, leukocytes 17.4[ncbi.nlm.nih.gov] Thrombotic thrombocytopenic purpura (TTP) and atypical hemolytic uremic syndrome (aHUS) are thrombotic microangiopathies (TMAs) that can present in pregnancy.[ncbi.nlm.nih.gov]

  • Acquired Toxic Hemolytic Anemia

    Membrane Burr Cells (Echinocytes) Spur Cells (Acanthocytes) Stomatocytes: mouth-shaped area of central pallor Target Cells: due to decreased lecithin/cholesterol acyltransferase[mdnxs.com] […] or fatigue; dizziness; shortness of breath with dyspnea on exertion; tachycardia, particularly at rest; palpitations; chest pain; new or accentuated cardiac murmur; and pallor[accessmedicine.mhmedical.com] […] or Band 3* 16 Clinical Manifestations of HS* Hemolytic anemia – Degree of anemia varies with different mutations – At least 25% with compensated hemolysis and no anemia Pallor[slideplayer.com]

  • Posthemorrhagic Anaemia of the Newborn

    Other findings include burr cells (uremia), spherocytes (hereditary spherocytosis, autoimmune hemolysis, G6PD deficiency), elliptocytes (hereditary elliptocytosis), schistocytes[aafp.org] Pallor persists in spite of administration of oxygen. Under such conditions immediate re-expansion of blood volume is imperative and lifesaving.[pediatrics.aappublications.org] Thrombocytopenic Purpura and Atypical Hemolytic Uremic Syndrome Microangiopathy in Pregnancy.[medicbind.com]

  • Congenital Heinz Body Hemolytic Anemia

    Burr Cells: Liver disease Renal disease Severe burns Bleeding gastric ulcers Maybe artifact Echinocyte (Burr Cell) Acanthocyte vs Echinocyte Howell-Jelly: are intracellular[medical-labs.net] In this condition, several cells, instead of having a central area of pallor, possess a central “slit” of pallor.[theartofmed.wordpress.com] thrombocytopenic purpura ) Presence of a type of immature red blood cells called normoblasts may be due to: Cancer that has spread to bone marrow Blood disorder called erythroblastosis[m.ufhealth.org]

  • Acquired Spherocytosis

    Crenated / Burr cells / Echinocytes (Echinocytes, or burr cells or crenated red cells, in contrast, have shorter, sharp to blunt spicules of uniform length which are more[slideshare.net] -Physical: Weakness, Pallor, Jaundice, Tachycardia -Labs: Down Hct, Up RC, Up Bilirubin -Diagnosis? Tests? Rx?[quizlet.com] Red cell morphology: eg, haemolytic uraemic syndrome, thrombotic thrombocytopenic purpura.[patient.info]

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