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48 Possible Causes for Burr Cell, Pulmonary Edema

  • Hemolytic Uremic Syndrome

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] . Complications of fluid overload may present with:  Pulmonary edema  Hypertensive encephalopathy Despite thrombocytopenia, bleeding manifestations are rare Neurological[slideshare.net] Title Other Names: HUS; Acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia associated with distorted erythrocytes ('burr cells') Categories: Hemolytic[rarediseases.info.nih.gov]

  • Preeclampsia

    […] hemodilution of pregnancy Peripheral smear (schistocytes, burr cells, echinocytes) Increased bilirubin ( 1.2 mg/dL) Thrombocytopenia ( 100,000) due to hemolysis and low platelet[emedicine.com] CASE REPORT: A 23-year-old pregnant woman with mitral regurgitation complicated with preeclampsia and pulmonary edema presented 2 episodes of atrial tachycardia induced by[ncbi.nlm.nih.gov] Chest plain film showed acute pulmonary edema, bilateral pulmonary infiltration with interstitial patches, and cardiomegaly.[ncbi.nlm.nih.gov]

  • Microangiopathic Hemolytic Anemia

    - schistocytes, “burr cells”, “helmet cells” and “triangle cells”. 6.[slideshare.net] These complications progressed despite cessation of chemotherapy, and all three patients died of noncardiogenic pulmonary edema precipitated in two cases by blood transfusions[ncbi.nlm.nih.gov] In some patients with chemotherapy-related MAklA, pulmonary edema or seizure was also observed.[e-crt.org]

  • HELLP Syndrome

    Burr cells Schistocytes Reticulocyte count – consider to evaluate for presence of hemolysis Liver enzymes AST – 2 times the upper reference limit meets criteria LDH – markedly[arupconsult.com] Pulmonary edema is easily managed by early hemodialysis.[ncbi.nlm.nih.gov] Laboratory studies should include: Complete blood cell (CBC) count Coagulation studies Peripheral smear for schistocytes, helmet cells, burr cells Liver function tests: serum[symptoma.com]

  • Uremic Pneumonitis

    Diagnosis Peripheral blood smear establishes the presence of MAHA by schistocytes, burr cells, helmet cells etc.[omicsonline.org] Etiology A 330 Pulmonary edema or left heart failure in infancy and childhood Various entities B 331 Unilateral pulmonary edema 332 Pulmonary hemorrhage in the older infant[books.google.de] They fulfilled the criteria for HUS [hemolytic anemia with microangiopathic changes on peripheral blood smear (Burr cells), acute renal failure, and thrombocytopenia] and[clinchem.aaccjnls.org]

  • Post-Infectious Glomerulonephritis

    Laboratory evaluation revealed micro-angiopathic anaemia with burr cells, thrombocytopenia, elevated lactic dehydrogenase and low complement C3.[ncbi.nlm.nih.gov] About 14% presented with complications (pulmonary edema-6%, seizure-1%, dialysis requiring renal failure-7%) and 9% had comorbid illness.[ncbi.nlm.nih.gov] edema, hypertensive encephalopathy or crescentic glomerulonephritis; children with obesity may have greater renal injuries ( Clin Nephrol 2009;71:632 ) Children age 6 - 10[pathologyoutlines.com]

  • Cor Pulmonale

    A peripheral blood smear revealed burr cells and schistocytes, suggesting microangiopathic hemolytic anemia (MAHA).[kjim.org] ‘Postoperatively, the patient was managed in the critical care unit for 15 days owing to a series of pulmonary complications including pneumonia, pulmonary edema, and cor[en.oxforddictionaries.com] ‘A 41-year-old man underwent a heart/lung transplant in February 1997 for idiopathic pulmonary fibrosis and cor pulmonale.’[en.oxforddictionaries.com]

  • Pregnancy-induced Hypertension

    Burr cells, schistocytes on PBS bilirubin 1.2mg/dl absent plasma haptoglobin2) Elevated liver enzymes AST 72 IU/L LDH 600 IU/L3)Low platelets 1 lakh/mm3 47.[slideshare.net] Severe pulmonary edema occurred in a patient during the third trimester of two consecutive pregnancies, 17 months apart.[ncbi.nlm.nih.gov] In general, the accepted values are as follows: Hematologic changes: Abnormal peripheral blood smear (schistocytes, burr cells, or echinocytes) Indirect bilirubin 1.2 mg/dL[clinicaladvisor.com]

  • Eclampsia

    […] hemodilution of pregnancy Peripheral smear (schistocytes, burr cells, echinocytes) Increased bilirubin ( 1.2 mg/dL) Thrombocytopenia ( 100,000) due to hemolysis and low platelet[emedicine.com] This caseemphasizes the importance of considering late postpartum eclampsia in patients presenting with signs of pulmonary edema even several days after delivery, as early[ncbi.nlm.nih.gov] The patient's maternal condition improved and was diagnosed with pulmonary edema and diabetic ketoacidosis.[ncbi.nlm.nih.gov]

  • Anemia

    Burr cells accompany renal failure and spur cells accompany severe liver disease.[cancertherapyadvisor.com] It is contraindicated in patients with pulmonary edema or a ruptured diaphragm. It is also contraindicated in pregnant patients.[emedicine.com] Elliptocytes or bizarre misshapen cells indicate inherited membrane disorders like elliptocytosis, pyropoikilocytosis, ovalocytosis, tomatocytosis, xerocytosis.[cancertherapyadvisor.com]

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