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54 Possible Causes for Burr Cell, Reticulocytes Increased

  • Hemolytic Uremic Syndrome

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] reticulocytes reduced haptoglobins increased LDH unconjugated hyperbilirubinaemia with urinary urobilinogen variable neutrophilia increased urea and creatinine levels (greater[lifeinthefastlane.com] Title Other Names: HUS; Acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia associated with distorted erythrocytes ('burr cells') Categories: Hemolytic[rarediseases.info.nih.gov]

  • Abetalipoproteinemia

    (burr cells) due to lipid membrane abnormalities Microscopic (histologic) description Marked fat vacuoles in apical villous cytoplasm, normal villi Positive stains Fat stains[pathologyoutlines.com] […] that may be done to help diagnose this condition include: Apolipoprotein B blood test Blood tests to look for vitamin deficiencies (fat-soluble vitamins A, D, E, and K) "Burr-cell[health.ridgeviewmedical.org] […] apoprotein B from intestinal mucosal cells As a result, free fatty acids and monoglycerides cannot be assembled into chylomicrons and become triglycerides stored within cells[pathologyoutlines.com]

  • HELLP Syndrome

    Burr cells Schistocytes Reticulocyte count – consider to evaluate for presence of hemolysis Liver enzymes AST – 2 times the upper reference limit meets criteria LDH – markedly[arupconsult.com] Blood smears have shown contracted red cells w/ spicula, polychromatic red cells, and increased reticulocyte counts.[physio-pedia.com] Laboratory studies should include: Complete blood cell (CBC) count Coagulation studies Peripheral smear for schistocytes, helmet cells, burr cells Liver function tests: serum[symptoma.com]

  • Leukoerythroblastic Anemia

    cells (echinocytes) may indicate: Uremia The presence of spur cells (acanthocytes) may indicate: Abetalipoproteinemia Severe liver disease The presence of teardrop-shaped[ucsfbenioffchildrens.org] An increased absolute number of reticulocytes indicates increased marrow erythropoiesis. u. Rouleaux: red cells in stacks, as coins.[kerrybrandis.com] They may be artefactual - see Crenated cells - or pathological - see Burr cells above.[patient.info]

  • Fetal Erythroblastosis

    Schistocytes, as a sign of disseminated intravascular coagulation and burr cells, are present, as well as neutropenia and thrombocytopenia.[symptoma.com] Peripheral blood morphology shows increased reticulocytes. Erythroblasts (also known as nucleated red blood cells) occur in moderate and severe disease.[moondragon.org] If there is extensive disseminated intravascular coagulation, schistocytes and burr cells may be observed and neutropenia and thrombocytopenia may occur.[patient.info]

  • Acquired Spherocytosis

    Crenated / Burr cells / Echinocytes (Echinocytes, or burr cells or crenated red cells, in contrast, have shorter, sharp to blunt spicules of uniform length which are more[slideshare.net] A complete blood count (CBC) may show increased reticulocytes, a sign of increased red blood cell production, and decreased hemoglobin and hematocrit.[en.wikipedia.org] If the reticulocyte count is low, the body is not able to keep up with the increased red blood cell production demands.[ihtc.org]

  • Cerebral Thrombotic Thrombocytopenic Purpura

    cells, helmet-shaped RBCs, normoblasts, reticulocytosis, unconjugated BR, Hb, hemosiderin, haptoglobin, proteinuria Management Corticosteroids, aspirin, dipyridamole, Igs[medical-dictionary.thefreedictionary.com] A number of findings can help to establish the diagnosis of TTP: The reticulocyte count is increased and correlates with the severity of the anemia.[epilepsy.com] RPI, due to the time that it takes to increase epo synthesis and increase bone marrow RBC production Hemolytic Anemia Reticulocyte Production Index MEDLINE ] Chronic Anemia[mdnxs.com]

  • Paroxysmal Cold Hemoglobinuria

    RBC survival may be shortened in renal failure (burr cells) and in liver disease (acanthocytes and target cells).[med-ed.virginia.edu] […] count – usually elevated Positive indicators of hemolysis – hyperbilirubinemia, increased lactate dehydrogenase Direct Coombs Establish presence of immunoglobins and complement[arupconsult.com] Normal reticulocyte percentage is 0.5 to 1.5% b.[errolozdalga.com]

  • Microangiopathic Hemolytic Anemia

    - schistocytes, “burr cells”, “helmet cells” and “triangle cells”. 6.[slideshare.net] Reticulocyte count 0.5-2.0% Increased Increase is inversely proportional to the degree of anemia.A normal bone marrow response to anemia is required for an increased reticulocyte[clinicaladvisor.com] -schistocytes -fragements -burr cells -microspherocytes What are some causes of microangiopathic hemolytic anemia?[quizlet.com]

  • Atypical Hemolytic Uremic Syndrome

    A peripheral blood smear (PBS) was performed, which contained schistocytes (32%) with helmet and burr cells.[ncbi.nlm.nih.gov] Lactate dehydrogenase was increased to 1084 U/L ( 460 U/L), reticulocyte count was 8.9%, and haptoglobin was less than 0.4 g/L (.1-.3 g/L).[doi.org]

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