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17 Possible Causes for Burr Cell, Scleral Icterus, Thrombotic Thrombocytopenic Purpura

  • Hemolytic Uremic Syndrome

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] Thrombotic thrombocytopenic purpura associated with ticlopidine-Thrombotic Thrombocytopenic Purpura (TTP) 271 a review of 60 cases. Ann Intern Med 1998;128: 541–544.[doi.org] Title Other Names: HUS; Acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia associated with distorted erythrocytes ('burr cells') Categories: Hemolytic[rarediseases.info.nih.gov]

  • Microangiopathic Hemolytic Anemia

    - schistocytes, “burr cells”, “helmet cells” and “triangle cells”. 6.[slideshare.net] The similarity of the mother's illness to thrombotic thrombocytopenic purpura and of the daughter's to adult hemolytic uremic syndrome suggests that these diseases are variants[ncbi.nlm.nih.gov] Our understanding of the pathogenesis of idiopathic thrombotic thrombocytopenic purpura (TTP) has increased, but remains incomplete, particularly with respect to cases of[ncbi.nlm.nih.gov]

  • Cholestasis of Pregnancy

    It is characterized by microangiopathic hemolysis with burr cells and schistocytes on peripheral smear; elevated liver enzyme levels, with aspartate transaminase (AST) exceeding[clevelandclinicmeded.com] thrombocytopenic purpura.[jsth.org] purpura, Thrombotic thrombocytopenic purpura, Anti-phospholipid antibody syndrome DIC 18.[slideshare.net]

  • Red Blood Cell Disorder

    Burr Cells: Liver disease Renal disease Severe burns Bleeding gastric ulcers Maybe artifact Echinocyte (Burr Cell) Acanthocyte vs Echinocyte Howell-Jelly: are intracellular[medical-labs.net] icterus (yellow eyes) Enlarged spleen Gallstones RBC disorders may be suspected based on the general findings of a complete medical history and physical exam.[danafarberbostonchildrens.org] Thrombotic thrombocytopenic purpura: A rare blood disorder causing small blood clots to form in blood vessels throughout the body.[calcuttayellowpages.com]

  • Congenital Heinz Body Hemolytic Anemia

    Burr Cells: Liver disease Renal disease Severe burns Bleeding gastric ulcers Maybe artifact Echinocyte (Burr Cell) Acanthocyte vs Echinocyte Howell-Jelly: are intracellular[medical-labs.net] Scleral icterus and/or jaundice may occur, and the spleen may enlarge.[merckmanuals.com] thrombocytopenic purpura ) Presence of a type of immature red blood cells called normoblasts may be due to: Cancer that has spread to bone marrow Blood disorder called erythroblastosis[m.ufhealth.org]

  • Uremic Anemia

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] Her exam was remarkable for mild scleral icterus, epigastric tenderness but no peritoneal signs.[bloodjournal.org] Thrombotic thrombocytopenic purpura (similar to hemolytic-uremic syndrome ) involves nonimmunologic platelet destruction.[merckmanuals.com]

  • Acquired Spherocytosis

    Crenated / Burr cells / Echinocytes (Echinocytes, or burr cells or crenated red cells, in contrast, have shorter, sharp to blunt spicules of uniform length which are more[slideshare.net] Scleral icterus and/or jaundice may occur, and the spleen may be enlarged.[msdmanuals.com] Red cell morphology: eg, haemolytic uraemic syndrome, thrombotic thrombocytopenic purpura.[patient.info]

  • Congenital Liver Cirrhosis

    It is characterized by microangiopathic hemolysis with burr cells and schistocytes on peripheral smear; elevated liver enzyme levels, with aspartate transaminase (AST) exceeding[clevelandclinicmeded.com] Thrombocytopenic Purpura Randomized Delayed-Start Trial of Levodopa in Parkinson’s Disease Challenge Yourself Interactive Medical Cases Image Challenge Videos in Clinical[nejm.org] Learning/CME Learning/CME View all learning/CME CME Case 3-2019: A 70-Year-Old Woman with Fever, Headache, and Progressive Encephalopathy Caplacizumab Treatment for Acquired Thrombotic[nejm.org]

  • Anemia

    Burr cells accompany renal failure and spur cells accompany severe liver disease.[cancertherapyadvisor.com] There is no scleral icterus. A CBC shows an Hgb level of 7.8 g per dL (78 g per L) and an MCV of 90 μm 3 (90 fL).[aafp.org] Hemolytic anemia This type of anemia includes sickle cell anemia, thrombotic thrombocytopenic purpura (TTP), hemolytic uremic syndrome, aortic valve prosthesis, disseminated[emedicine.com]

  • Atypical Hemolytic Uremic Syndrome

    A peripheral blood smear (PBS) was performed, which contained schistocytes (32%) with helmet and burr cells.[ncbi.nlm.nih.gov] Upon presentation, she was in fact noted to have scleral icterus and mild epigastric abdominal tenderness.[pubs.sciepub.com] Thrombotic thrombocytopenic purpura (TTP) and atypical hemolytic uremic syndrome (aHUS) are thrombotic microangiopathies (TMAs) that can present in pregnancy.[ncbi.nlm.nih.gov]

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