C-Reactive Protein Increased: Causes & Reasons

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Possible Causes for C-Reactive Protein Increased

Muckle-Wells Syndrome

Tests that show a high erythrocyte sedimentation rate (measures how quickly erythrocytes settle at the bottom of a test tube, high values indicate inflammation), C-reactive [rarediseasereview.org]

C-reactive protein). [jacionline.org]

Also, they have increased erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and serum amyloid A (SAA). [symptoma.com]

Polyarthritis

Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and leukocytes were increased. [ncbi.nlm.nih.gov]

Mild leukocytosis and increased C-reactive protein concentration were revealed in blood work. [dbpia.co.kr]

The erythrocyte sedimentation rate was increased at 64 mm in the first hour and C reactive protein at 88 mg/ml. [ard.bmj.com]

Multicentric Castleman's Disease

C-reactive protein (CRP). [ncbi.nlm.nih.gov]

It manifests by fever, diffuse lymphadenopathy, hepatosplenomegaly, Involvement of the respiratory system and increased C-reactive protein. [orpha.net]

Nevertheless, his general condition, including pleural effusion and ascites, worsened, and C-reactive protein and interleukin-6 levels showed marked increases. [ncbi.nlm.nih.gov]

CINCA Syndrome

[…] in the number of white blood cells Elevation in levels of the protein amyloid A and C-reactive protein in the blood and an increase in the erythrocyte sedimentation rate [patientworthy.com]

Inflammatory blood tests like the white blood cell count, erythrocyte sedimentation rate and the C-reactive protein are increased during attacks. [my.clevelandclinic.org]

[…] result in vision and hearing loss Joint inflammation and joint and bone deformities Enlargement of the knee-cap Stunted growth Enlargement of the liver and spleen Abnormal increase [patientworthy.com]

Vasculitis

Mild leukocytosis—with or without eosinophilia—and increased acute-phase indicators, such as erythrocyte sedimentation rate (ESR) or C-reactive protein, are typical but non-specific [worldallergy.org]

Their results will generally show signs of inflammation in the body, such as increased erythrocyte sedimentation rate (ESR), elevated C-reactive protein (CRP), anemia, increased [en.wikipedia.org]

Active vasculitis is usually associated with an acute phase response with an increase in C reactive protein concentration, erythrocyte sedimentation rate, or plasma viscosity [bmj.com]

COVID-19

[…] in 3 cases (3/20, 15%); alanine aminotransferase increased in 5 cases (5/20, 25%); creatine kinase‐MB increased in 15 cases (15/20, 75%); C‐reactive protein (CRP) increased [onlinelibrary.wiley.com]

Common laboratory findings in COVID-19 are a decreased lymphocyte count and an increased CRP and high-sensitivity C-reactive protein level. [radiologyassistant.nl]

Meanwhile, patients might show normal or lower white blood cell counts, lymphopenia, or thrombocytopenia, with extended activated thromboplastin time and increased C-reactive [pubs.rsna.org]

Childhood Hodgkin Lymphoma

Hypoalbuminemia, as well as increased acute-phase reactants (C-reactive protein, erythrocyte sedimentation rate, ferritin, and copper), are other usual findings. [symptoma.com]

Microscopic Polyangiitis

Eleven patients experienced weight loss, several had kidney involvement, and most had an increased erythrocyte sedimentation rate and C-reactive protein. [ncbi.nlm.nih.gov]

Four years later, purpura, peripheral neuropathy, and increased levels of myeloperoxidase anti-neutrophil cytoplasmic antibodies (583 EU/mL) and C-reactive protein (2.27 mg [ncbi.nlm.nih.gov]

In the CY group, the hazard ratio after adjusting for age, sex, Birmingham vasculitis activity score values, serum albumin levels and C-reactive protein (CRP) levels was 0.657 [ncbi.nlm.nih.gov]

Osteoarthritis

Increased serum C-reactive protein levels by immunonephelometry in patients with rapidly destructive hip osteoarthritis. Rev Rhum Engl Ed. 1998;65:759–765. [doi.org]

Low level increases in serum C-reactive protein are present in early osteoarthritis of the knee and predict progressive disease.Arthritis Rheum. 1997; 40: 723-727 25. [thelancet.com]

Both groups exhibited a nonsignificant increase in high-sensitivity C-reactive protein (0.2 vs 0.1 mg/L; between-group mean difference, −0.1 mg/L; 95% CI, −0.4 to 0.2 mg/L [doi.org]

Cryopyrin-Associated Periodic Syndrome

Acute phase reactants in blood, such as erythrocyte sedimentation rate ( ESR ), C-reactive protein ( CRP ) and serum amyloid A (SAA), are markedly increased, even when the [dermnetnz.org]

Acute phase reactants in blood, such as erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and serum amyloid A (SAA), are markedly increased, even when the patient [dermnetnz.org]

reactive protein and serum amyloid A). [orpha.net]

Ulcerative Colitis

Moreover, doctors can check blood samples for signals of inflammation, such as C-reactive protein or an increased number of white blood cells, Arsenescu told Live Science. [livescience.com]

Laboratory studies showed elevated C-reactive protein (CRP, 42 mg/l), fecal-calprotectin (7,223 μg/g), and anemia (hemoglobin 10.4 g/dl). [ncbi.nlm.nih.gov]

She was afebrile with increased heart rate (96/min). [ncbi.nlm.nih.gov]

Bacterial Pneumonia

Concentrations of serum clozapine, C-reactive protein (CRP) and alpha1 acid glycoprotein were greatly increased during a bacterial pneumonia in a 53-year-old woman. [ncbi.nlm.nih.gov]

Whipple Disease

Laboratory tests on admission to the hospital displayed an increased C-reactive protein level (18.6 mg/l: normal range -5) and an elevated leukocyte count (11.3 × 10 9 leucocytes [jmedicalcasereports.com]

Regarding laboratory findings, hypochromic anemia, limphocytopenia, thrombocytosis, increased C-reactive protein levels, vitamin deficiency, or indirect signs of malabsorption [scielo.isciii.es]

Laboratory results included: ESR at 1 st hour 15 mm; C-reactive protein 74 mg/L; the remaining parameters were normal. A chest PA showed no remarkable findings. [scielo.isciii.es]

Cerebral Angiitis

When cerebral affection occurs in systemic vasculitis an acute inflammatory response with raised erythrocyte sedimentation rate and increased values of C-reactive protein [ncbi.nlm.nih.gov]

Laboratory findings suggestive of a systemic vasculitis include an acute inflammatory response with raised erythrocyte sedimentation rate (ESR) and increased values of C-reactive [ncbi.nlm.nih.gov]

protein (CRP). [ncbi.nlm.nih.gov]

Pseudomonas Aeruginosa

The inflammatory markers, C-reactive protein and procalcitonin, were markedly raised, at 231 mg/L and 217 ng/mL, respectively. Chest x-ray revealed pulmonary edema. [ncbi.nlm.nih.gov]

An uncompensated metabolic acidosis, hyponatremia, renal failure, and increased liver enzyme levels were observed. [ncbi.nlm.nih.gov]

Arthritis of Knee

BMI, triglycerides, and C-reactive protein. [medicalnewstoday.com]

[…] being aged from 30 to 50 year People with psoriatic arthritis tend to have a higher number of risk factors for cardiovascular disease than the general population, including increased [medicalnewstoday.com]

Pancreatitis

Laboratory studies revealed mild leukocytosis, increased levels of serum lipase, amylase, and C-reactive protein (CRP). [ncbi.nlm.nih.gov]

In patients with a severe form of the disease, they will have an elevated C-reactive protein level, an increase in hematocrit above 44%, and a body mass index greater than [physio-pedia.com]

Polyarticular Juvenile Idiopathic Arthritis

The laboratory findings highlighted that; increase in C-reactive protein (CRP) 25 (92.5%), leukocytosis 2 (7.1%), thrombocytosis 21 (75%) and anemia 22 (78.5%) were observed [elynsgroup.com]

C-reactive protein (CRP) is a protein that the liver releases into the blood at the start of infection or inflammation; this level can rise if a person is having an arthritis [kidshealth.org]

This rate often increases in people when inflammation is occurring in the body. [kidshealth.org]

Oligoarthritis

Initial laboratory evaluation showed an increase of acute phase reactants (C reactive protein 218 mg/dL with normal references 0-5 mg/dL, and erythrocyte sedimentation rate [scielo.org.co]

C-reactive protein (CRP) is a protein that the liver releases into the blood at the start of infection or inflammation; this level can rise if a person is having an arthritis [m.kidshealth.org]

This rate often increases in people when inflammation is occurring in the body. [m.kidshealth.org]

Systemic Juvenile Idiopathic Arthritis

Laboratory findings may reveal increased white blood cell count and markers of inflammation such as erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and fibrinogen [symptoma.com]

[…] serum ferritin or C-reactive protein levels. 5, 7 These findings suggest that elevated serum concentrations of IL-18 would be closely specific for AOSD among systemic inflammatory [nature.com]

Several investigators also demonstrated that serum IL-18 was increased in AOSD patients compared to other systemic inflammatory diseases and that it was well correlated to [nature.com]

T-Cell Lymphoblastic Lymphoma

Routine lab tests were normal except for C-reactive protein test (CRP) of 24.27 mg/L (normal is up to 5 mg/L). Liver function tests and coagulation profile were normal. [cureus.com]

Peripheral smear showed hypochromia, anisocytosis and microcytosis, few reactive lymphocytes and increased platelets. [cureus.com]

Lyme Disease

[…] in TNF-α, IL-1β, IL-6, IL-8, IL-12, IL-17, IL-18, interferon-gamma, neopterin, C-reactive protein, surface lipoprotein E, and the chemokines CXCL12 and CXCL13, release of [ncbi.nlm.nih.gov]

[…] periphery can also provoke significant immune activity that crosses the blood–brain barrier. 13 These immune-mediated effects include activation of proinflammatory cytokines and increases [ncbi.nlm.nih.gov]

Gaucher Disease

C-reactive protein (CRP; 10.8 mg/dl; normal volunteers <0.5 mg/dl). [touchoncology.com]

[…] hepatosplenomegaly, leukocytosis with lymphocytosis (white blood cell count [WBC] 30,130/μl; L 73%), microcytic anaemia (Hb 8 g/dl; MCV 63 fl), thrombocytopenia (114,000/μl) and increased [touchoncology.com]

Gastrointestinal Stromal Tumor

Signs of inflammation were positive: erythrocyte sedimentation rate (ESR) 109, fibrinogen 6.9 g/l, C-reactive protein 249 mg/l, and procalcitonin was increased 0.622 ng/ml [go.galegroup.com]

Enthesitis-Related Arthritis

C-reactive protein (CRP) is a protein that the liver releases into the blood at the start of infection or inflammation; this level can rise if a person is having an arthritis [kidshealth.org]

This rate often increases in people when inflammation is occurring in the body. [kidshealth.org]

Metastatic Renal Cell Carcinoma

protein. [symptoma.com]

[…] has been shown to release interleukins IL-1 and IL-6 as well as tumor necrosis factor-α, and these have been related to enhanced concentrations of acute phase markers like C-reactive [symptoma.com]

Moreover, tumor cells may release parathyroid hormone-related peptide and renin production by the affected kidneys may be increased. [symptoma.com]

Adenosine Deaminase Deficiency

C-reactive protein (CRP), leukocytes and platelets count were increased in high levels of synovial fluid ADA. [ijp.tums.pub]

Necrotizing Enterocolitis

Other common laboratory findings include elevated C-reactive protein (CRP), thrombocytopenia, metabolic acidosis, high or low blood glucose, and electrolyte imbalances. [journals.lww.com]

NEC, laboratory findings, when paired with physical examination and radiographic findings, can aid in substantiating the diagnosis. 3 An infant with NEC may exhibit either increased [journals.lww.com]

Nakajo Syndrome

Laboratory findings include constantly elevated C-reactive protein (CRP) levels and hyper-gamma-globulinemia. [orpha.net]

Autoantibody titers increase as the disease progresses in some but remain negative in others. [orpha.net]

Gaucher Disease Type 1

C-reactive protein (CRP; 10.8 mg/dl; normal volunteers <0.5 mg/dl). [touchoncology.com]

Acute phase reactants were slightly increased: erythrocyte sedimentation rate was 62 mm/1 h and C-reactive-protein level 1.24 mg/dL (normal values < 0,46 mg/dL). [hindawi.com]