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65 Possible Causes for C-Reactive Protein Increased, Hand Stiffness, Progressive Contractures

  • Osteoarthritis

    Increased serum C-reactive protein levels by immunonephelometry in patients with rapidly destructive hip osteoarthritis. Rev Rhum Engl Ed. 1998;65:759–765.[doi.org] Another characteristic symptom of the disease is the progressive incapacity of the joint to function, leading – in the long run – to loss of mobility.[oafifoundation.com] Fingers and Hands When OA occurs in hands and fingers, you may experience stiffness, numbness, and aching.[arthritis.com]

  • Polyarthritis

    Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and leukocytes were increased.[ncbi.nlm.nih.gov] The characteristic rapid progression of palmar contracture is a key finding that suggests the potential existence of a malignancy. [Indexed for MEDLINE] Free full text[ncbi.nlm.nih.gov] CASE 2 A 86 year old white man presented with a three week history of severe swelling of the right hand associated with pain and morning stiffness.[ard.bmj.com]

  • Enthesitis-Related Arthritis

    C-reactive protein (CRP) is a protein that the liver releases into the blood at the start of infection or inflammation; this level can rise if a person is having an arthritis[kidshealth.org] A subset of children with ERA will progress to ankylosing spondylitis (AS), a condition characterized by spinal and back pain, stiffness, and eventual fusion of the vertebra[grantome.com] Symptoms can involve the hands, feet, and knees, but any joint can be involved.[childrenshospital.org]

  • Scleroderma

    protein ( CRP ), positive Rheumatoid factor, increased gamma globulins (hypergammaglobulinaemia) and abnormal coagulation tests may be present.[dermnetnz.org] […] may occur when the skin overlying joints is involved. 16 Reports of progression to systemic scleroderma in the pediatric population are exceedingly rare. 3, 12, 21 Adequate[pediatrics.aappublications.org] […] disorders, including scleromyxedema, scleredema, nephrogenic systemic fibrosis, eosinophilic fasciitis, chronic graft-versus-host disease, porphyria cutanea tarda, diabetic stiff-hand[ncbi.nlm.nih.gov]

  • Arthritis

    protein [CRP]) Increased clinical severity.[en.wikipedia.org] Flexion contractures may require intensive exercise, casting, or immobilization (eg, splinting) in progressively more stretched-open positions.[merckmanuals.com] The warning signs for either form are joint swelling, particularly in the hands and feet, and early morning stiffness that lasts more than half an hour.[dailymail.co.uk]

  • Polyneuropathy

    Routine laboratory findings, including serum complete blood count, biochemistry, urine analysis and C-reactive protein, were normal.[bmcneurol.biomedcentral.com] Rehabilitation When the CIDP condition is under controlled, early start of exercises of neurological rehabilitation can prevent muscle atrophy and contractures.[nnjournal.net] Then, muscles may become stiff and permanently shortened (called contractures).[msdmanuals.com]

  • Frozen Shoulder

    protein as well as an increase incidence of HLA-B27 histocompatibility antigen often seen in patients with this condition.[symptoma.com] Idiopathic frozen shoulder is a common cause of severe and prolonged disability characterised by spontaneous onset of pain with progressive shoulder movement restriction.[ncbi.nlm.nih.gov] Since it doesn't get as much use, the shoulder that is opposite the favored hand—usually the left shoulder in right-handed people—is the one most often affected.[healthcommunities.com]

  • Nakajo Syndrome

    Laboratory findings include constantly elevated C-reactive protein (CRP) levels and hyper-gamma-globulinemia.[orpha.net] Definition An autosomal recessive autoinflammatory disorder characterized by early childhood onset of recurrent fever, joint stiffness and severe contractures of the hands[uniprot.org] Tight Achilles tendon was noted and progressed to bilateral ankle contractures 1 year later.[academic.oup.com]

  • Osteoarthritis of the Knee

    In knee osteoarthritis, high-sensitivity C-reactive protein concentration may increase in early-stage KL-II. The Author(s) 2015.[ncbi.nlm.nih.gov] , knee ROM, medial BMLs, medial subchondral bone cysts and medial trabecular bone texture are associated with the cOA progression.[arthritis-research.biomedcentral.com] […] knobs at the middle finger joints (known as Bouchard's nodes ) and at the farthest finger joints (known as Heberden's nodes ) are a common feature of osteoarthritis in the hands[en.wikipedia.org]

  • Calcium Pyrophosphate Arthropathy

    Occasionally, a gout attack triggers a systemic inflammatory response manifesting with fevers, leukocytosis, elevated sedimentation rates, and elevated C-reactive protein[clevelandclinicmeded.com] Signs: Pseudo-Rheumatoid (5% of CPPD Deposition Disease) Symmetric Polyarthritis with low grade inflammation Synovial thickening Flexion contractures Morning Stiffness Fatigue[fpnotebook.com] Rheumatoid arthritis causes chronic swelling, heat, morning stiffness and pain in the joints and can also involve other tissues.[orthop.washington.edu]

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