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33 Possible Causes for C1 Esterase Inhibitor Decreased

  • Angioedema

    The vast majority of cases result from mutations affecting SERPING1 which encodes C1 esterase inhibitor (C1INH).[bitesized.immunology.org] Angioedema caused by decreased functional C1-esterase inhibitor (C1-INH) is covered elsewhere as well (see Hereditary Angioedema [HAE] and Acquired Angioedema [AAE]).[emedicine.medscape.com] Mutations can result in either low levels of C1INH (approx. 85% of cases) or normal levels of C1INH but with decreased function (approx. 15% of cases).[bitesized.immunology.org]

  • Hereditary Angioedema

    Hereditary angioedema (HAE) results from mutations in the C1-esterase inhibitor (C1 INH) gene that decrease production of C1 INH or render it dysfunctional.[ncbi.nlm.nih.gov] In HAE, mutations in the C1 esterase inhibitor (C1-INH) gene result in decreased C1-INH concentrations (type I HAE) or functionally deficient C1-INH (type II HAE), leading[ncbi.nlm.nih.gov] Hereditary angioedema (HEA) is a disease characterized by decreased levels or function of C1 esterase inhibitor (C1-INH).[ncbi.nlm.nih.gov]

  • Hereditary Angioedema Type 1

    inhibitor (C1-INH), complement 4 (C4) Decreased levels suggest hereditary angioedema Confirm with repeat testing of C1-INH and C4 If family history present, consider functional[arupconsult.com] HAE is caused by a deficiency of the C1 esterase inhibitor (C1‐inh) or decreased function of C1‐inh.[intechopen.com] The vast majority of cases result from mutations affecting SERPING1 which encodes C1 esterase inhibitor (C1INH).[immunology.org]

  • Hyperkalemia

    Upper airway edema can also be a sign in angiotensin converting enzyme inhibitor-induced angioedema or C1 esterase inhibitor deficiency with spontaneous laryngeal edema. 58[doi.org] If not promptly corrected, vasodilation and increased capillary permeability, causing decreased preload and relative hypovolemia of up to 37% of circulating blood volume,[doi.org]

  • Acquired Angioedema

    INTRODUCTION: Acquired angioedema is a rare disorder causing recurrent life-threatening angioedema, due to decreased activity of C1 esterase inhibitor.[ncbi.nlm.nih.gov] It has been 50 years since HAE was linked to a decrease of C1INH (the inhibitor of complement enzyme, C1 esterase), a link that provided for the first laboratory test available[ncbi.nlm.nih.gov] The C1 esterase inhibitor (C1-INH) protein levels were normal with decreased level of activity due to antibodies against C1 esterase inhibitor protein causing dysfunctional[ncbi.nlm.nih.gov]

  • Overdose

    Upper airway edema can also be a sign in angiotensin converting enzyme inhibitor-induced angioedema or C1 esterase inhibitor deficiency with spontaneous laryngeal edema. 58[doi.org] If not promptly corrected, vasodilation and increased capillary permeability, causing decreased preload and relative hypovolemia of up to 37% of circulating blood volume,[doi.org]

  • Cardiopulmonary Resuscitation

    Upper airway edema can also be a sign in angiotensin converting enzyme inhibitor-induced angioedema or C1 esterase inhibitor deficiency with spontaneous laryngeal edema. 58[doi.org] If not promptly corrected, vasodilation and increased capillary permeability, causing decreased preload and relative hypovolemia of up to 37% of circulating blood volume,[doi.org]

  • Hereditary Angioedema Type 3

    The determination of C1q is useful in the diagnosis of acquired AE due to C1-esterase inhibitor deficiency, in which it is decreased.[isithereditary.com] inhibitor (C1-INH), complement 4 (C4) Decreased levels suggest hereditary angioedema Confirm with repeat testing of C1-INH and C4 If family history present, consider functional[arupconsult.com] HAE is caused by a deficiency of the C1 esterase inhibitor (C1‐inh) or decreased function of C1‐inh.[intechopen.com]

  • Urticaria

    Decreased of C1 esterase inhibitor,C2 and C4 complement components.[drmhijazy.com]

  • Erythroderma Desquamativum

    Decreased of C1 esterase inhibitor,C2 and C4 complement components.[drmhijazy.com]

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