Create issue ticket

184 Possible Causes for Cafe-Au-Lait Spots, Childhood Cancer, Pallor

  • Tuberous Sclerosis

    Additional skin lesions may also develop, including cafe-au-lait spots; fibromas (benign, fibrous nodules) arising around or beneath the nails; or shagreen patches (rough,[flybase.org] Differentials to exclude: Neurofibromatosis type 1: Cafe au lait spots, neurofibromas, axillary freckling, lisch nodules.[ptpaces.wordpress.com] These are known as cafe-au-lait spots. A child may also have skin tumors that are not cancer (benign). These are called neurofibromas.[urmc.rochester.edu]

  • Neurofibromatosis Type 1

    Von Recklinghausen's disease or neurofibromatosis 1 is an autosomal dominant disorder with multiple neurofibromas and schwannomas, along with cafe au lait spots and axillary[medical-dictionary.thefreedictionary.com] Hawkins , Risk of bladder tumours after childhood cancer: The British Childhood Cancer Survivor Study , BJU International , 106 , 7 , (1060-1069) , (2010) . L.[doi.org] Physical findings include visual loss, loss of color vision, an afferent pupillary defect, and optic nerve pallor or atrophy.[emedicine.com]

  • Pheochromocytoma

    The subject should be examined for cafe au lait spots if neurofibromatosis is suspected.[clinicalpainadvisor.com] The National Registry of Childhood Cancers reports an incidence of 0.11 benign and 0.02 malignant pheochromocytomas per 1 million children.[pedsinreview.aappublications.org] BACKGROUND: Pheochromocytoma is an endocrine tumor that causes hypertension, facial pallor, and headache.[ncbi.nlm.nih.gov]

  • Bloom Syndrome

    Bloom syndrome is a rare autosomal recessive disorder characterized by short stature, brachydactyly, malar hypoplasia and facial telangiectasia, erythema and cafe au lait[radiopaedia.org] As a result, the best and brightest scientific discoveries for childhood cancers never actually make it into the clinic.[consano.org] […] for signs/symptoms incl hematuria & a painless abdominal mass Every 3 mos from time of diagnosis to age 8 yrs Leukemia Screening & family education on signs/symptoms incl pallor[ncbi.nlm.nih.gov]

  • Noonan Syndrome-Like Disorder with Juvenile Myelomonocytic Leukemia

    […] cardiac, cardiac malformation, developmental, genetic, neoplastic, neurological Phenotypes Aortic valve stenosis ; Autosomal dominant inheritance ; Bicuspid aortic valve ; Cafe-au-lait[mousephenotype.org] He’s also learned what it’s like to have childhood cancer.[stbaldricks.org] […] neurofibromatosis 1 and deletion of NF1 gene Due to stem cell defect causing deranged hematopoiesis Varied clinical presentation may include failure to thrive, malaise, fever, bleeding, pallor[pathologyoutlines.com]

  • Congenital Aplastic Anemia

    […] anemia Cause is chromosome breakage and defective repair Autosome recessive, few X-linked recessive Pancytopenia is seen first decade of life Congenital abnormalities – cafe-au-lait[pediatriceducation.org] Survey of childhood cancer survivors who stopped follow-up physician visits. Pediatr Int. 2010 Oct;52(5):806-12. 11.[med.nagoya-u.ac.jp] Low counts of red blood cells bring about anemia and cause fatigue, weakness and pallor.[symptoma.com]

  • Gardner Syndrome

    Additional symptoms associated with Turcot syndrome include small, coffee-colored spots on the skin (cafe-au-lait spots), the formation of multiple, benign fatty tumors (lipomas[rarediseases.org] This process most often begins in childhood. If left in place, the chance that a polyp will transform into cancer by age 40 approaches 100%.[mygenecounsel.com] Signs and symptoms of gastric cancer include the following: Indigestion Nausea or vomiting Dysphagia Postprandial fullness Loss of appetite Melena or pallor from anemia Hematemesis[emedicine.medscape.com]

  • Klippel-Trenaunay-Weber Syndrome

    She had no cafe au lait spots or axillary pigmentation. Her face showed mild asymmetry, with the left side larger than the right. Her development had been normal.[healio.com] Examination of the child revealed a conscious, slightly distressed child with moderate pallor and fever.[ijdvl.com] […] excavations of both eyes, with increased excavation / disc ratio in RE, denudation of circunlinear vessel, diffuse arteriolar narrowing, peripapillary atrophy, and located pallor[scielo.br]

  • Acute Myelomonocytic Leukemia

    Skin involvement is apparent in about one half of the patients, with maculo-papular rash (often starting from the face) and xanthomas, or cafe-au-lait spots, seen in patients[bloodjournal.org] Subsequent neoplasms in 5-year survivors of childhood cancer: the Childhood Cancer Survivor Study. J Natl Cancer Inst . 2010;102(14):1083–1095. 24.[aafp.org] Primary manifestations include mucosal pallor secondary to anemia, odontalgia, ulceration of the palate, gingival bleeding, gingivitis, petechiae and ecchymoses of the hard[cda-adc.ca]

  • Ataxia Telangiectasia

    .); the Department of Pathology and Center for Childhood Cancer Research of the Children’s Hospital of Philadelphia, and the Abramson Family Cancer Research Institute (to[doi.org] An otherwise seemingly normal girl, who had developed limping at the age of 11 months old, referred to Namazi Hospital, Shiraz, Iran, due to pallor and latitude at the age[ncbi.nlm.nih.gov] […] in childhood.[ambrygen.com]

Similar symptoms