Create issue ticket

63 Possible Causes for Cafe-Au-Lait Spots, Dark Skin Pigmentation, Pallor

  • Neurofibromatosis Type 1

    Von Recklinghausen's disease or neurofibromatosis 1 is an autosomal dominant disorder with multiple neurofibromas and schwannomas, along with cafe au lait spots and axillary[] Photographs of dermal neurofibromas (tumors of the skin), cafe-au-lait spots (dark or pigmented areas on the skin that are often the first signs of NF1) and other skin problems[] Physical findings include visual loss, loss of color vision, an afferent pupillary defect, and optic nerve pallor or atrophy.[]

  • Watson Syndrome

    From Wikidata Jump to navigation Jump to search No description defined WATSON SYNDROME; WTSN WATSON SYNDROME Pulmonic Stenosis With Cafe-Au-Lait Spots Cafe-Au-Lait Spots With[] […] stationary night blindness, golden yellow fundus in light that disappears in dark adaptation (Mizuo-Nakamura phenomenon) AR SAG, GRK1 #258100, #613411 OPTIC ATROPHY Optic nerve pallor[] Symptoms Café au lait spots In Watson syndrome cafe-au-lait spots are associated with pulmonic stensis. Systematic References: 1.[]

  • Neurofibromatosis Type 6

    MalaCards based summary : Autosomal Dominant Café Au Lait Spots, also known as neurofibromatosis type 6, is related to cafe-au-lait spots, multiple and pulmonary valve disease[] It is indicated for optic nerve pallor, visual changes, proptosis, or precocious puberty.[] Cafe-au-lait spots are flat brown skin spots. They are called “cafe-au-lait” from the French term for “coffee with milk”, because of their color.[]

  • Incontinentia Pigmenti Achromians

    Hypomelanosis of Ito associated with cafe-au-lait spot and angiomatous nevi.[] pigmentation (hyperpigmentation).[] Stage 1 is characterized by erythema, vesicles, and pustules; stage 2 by papules, verrucous lesions, and hyperkeratosis; stage 3 by hyperpigmentation; and stage 4 by pallor[]

  • Multiple Hamartoma Syndrome

    […] report, have most of the previously reported findings associated with this syndrome and several important unreported findings that include multiple cutaneous trichilemmomas, cafe-au-lait[] Clinical examination revealed multiple tiny (1-2 mm) nodules on forehead, nose, and maxillary region with pallor (anemia).[] […] macules; Pediatr Clin North Am. 2010 Oct;57(5):1131-53. doi: 10.1016/j.pcl.2010.07.002, Retrieve from: William D James, (2016); Cafe Au Lait Spots; Retrieve from: Marcia[]

  • Systemic Scleroderma

    The skin can lose or gain pigment; making areas of light or dark skin. Some people lose hair on the limbs, sweat less, and develop dry skin because of skin damage.[] Even among patients who do not experience all of the skin changes associated with Raynaud’s phenomenon, most report digital pallor 11 (see Figure 3).[] ] Nail-fold capillary dilatation and capillary destruction (see image below) Raynaud phenomenon of the hands: Symmetrical acral vasospasm is present, with characteristic pallor[]

  • Addison's Disease

    Even people with dark skin can develop excessive pigmentation, although the change may be harder to recognize.[] ) skin, and dark freckling.[] Corticotropin also stimulates melanin production, so the skin and the lining of the mouth often develop a dark pigmentation.[]

  • Fanconi Anemia

    Other abnormalities seen are skin pigmentation (Cafe au lait spot), small head (microcephaly), small eyes (microphthalmia), learning disabilities, failure to gain weight,[] Low platelet count (thrombocytopenia) Areas of abnormal skin pigmentation Frequent or unexpected nosebleeds Thumb abnormalities (see photos) Increased deep tendon reflexes[] Examination revealed pallor, short stature and thumb polydactyly. There was no visceromegaly or lymphadenopathy.[]

  • Neurofibromatosis Type 2

    Patient one presented to ophthalmology at the age of 2 years; by 4 years, he developed what was thought to be a plexiform neurofibroma and, with more than 6 cafe au lait spots[] ), dark, rough areas of hairy skin.[] It is indicated for optic nerve pallor, visual changes, proptosis, or precocious puberty.[]

  • Plexiform Neurofibroma

    Neurofibromatosis (NF) is a genetically inherited, autosomal dominant disease, characterized by multiple cafe au lait spots, cutaneous neurofibromas and "Lisch nodules."[] (pigmented neurofibroma) has led to considerable confusion in the literature.[] It is indicated for optic nerve pallor, visual changes, proptosis, or precocious puberty.[]

Similar symptoms