Calcitonin Decreased: Causes & Reasons

Warning: Do not use in emergencies, if pregnant, if under 18, or as a substitute for a doctor’s advice or diagnosis. Learn more

Possible Causes for Calcitonin Decreased

Primary Hyperparathyroidism

The patient received intramuscular injection of Miacalcic and incense of Calcitonin (Salmon) Nasal Spray to decrease serum calcium level. [ncbi.nlm.nih.gov]

Review Topic QID: 101951 1 PTH binding to receptors on osteoclasts 2 Parafollicular, or C-cell, synthesis of calcitonin 3 Increased RANK-L production 4 Decreased M-CSF production [medbullets.com]

Phosphate Diabetes

calcitonin, and vitamin D. [pubmed.ncbi.nlm.nih.gov]

Factors that decrease phosphate reabsorption include a high intake of dietary phosphate, acidosis, parathyroid hormone (PTH), PTH-related peptide (PTHrp), glucocorticoid therapy [pubmed.ncbi.nlm.nih.gov]

Hypercalcemia

After commencement of calcitonin treatment, her ionized calcium level decreased to normal reference ranges. [ncbi.nlm.nih.gov]

Other commonly used medications to further decrease calcium include bisphosphates, calcitonin, steroids, and (rarely) furosemide. [ncbi.nlm.nih.gov]

Hypercalcemia → calcitonin release → decreased plasma calcium. [vetstream.com]

Medullary Thyroid Carcinoma

CEA and serum calcitonin decreased significantly postthyroidectomy, and no further fracture has been reported by the patient so far. [ncbi.nlm.nih.gov]

Following successful surgical removal of medullary carcinoma, plasma calcitonin levels gradually decrease into the undetectable range over a period of several weeks. [clinlabnavigator.com]

Adults with medullary thyroid carcinoma with a large tumor size, high calcitonin level and cervical metastases have a decreased 5-year survival compared with those with smaller [healio.com]

Idiopathic Juvenile Osteoporosis

[…] on bone biopsy, and the fracture rate did not decrease. [ncbi.nlm.nih.gov]

[…] levels. 1,25-Dihydroxyvitamin D values were low in three patients and slightly decreased in one. [ncbi.nlm.nih.gov]

After the onset of puberty, endogenous calcitonin was detectable. [ncbi.nlm.nih.gov]

Ovarian Hyperfunction

For example, medullary carcinomas of the thyroid originate from C cells (parafollicular cells) that normally produce calcitonin, a hormone that transiently decreases serum [britannica.com]

These tumours may produce not only calcitonin but also adrenocorticotropin, which is normally secreted by cells of the pituitary gland. [britannica.com]

decreases serum calcium concentrations by promoting uptake of calcium into bone tissue and excretion of calcium in the urine skin, liver, kidneys calciferols (vitamin D) [britannica.com]

Hungry Bones Syndrome

Calcitonin C. Decreased dosage of levothyroxine D. [acphospitalist.org]

It is caused primarily by precipitation of calcium soaps in the abdominal cavity, but glucagon-stimulated calcitonin release and decreased PTH secretion may play a role. [emedicine.medscape.com]

Calcitonin decreases bone resorption by attenuating osteoclast activity. [acphospitalist.org]

Hypercalcemia of Malignancy

In addition to rehydration and furosemide, treatment with eel-calcitonin and prednisolone failed to decrease his serum calcium level. [ncbi.nlm.nih.gov]

Calcitonin is useful if a rapid decrease in serum calcium is necessary, but tachyphylaxis limits its use. [ncbi.nlm.nih.gov]

An initial decrease in serum calcium was observed with intravenous fluids, pamidronate, and calcitonin, but the normalization slowed and reversed within 3 days. [ncbi.nlm.nih.gov]

Neonatal Hypocalcemia

calcitonin concentration does not correlate with the elevated serum gastrin and plasma glucagon values; and at 24 hours of age, decreased serum Ca is correlated with serum [ncbi.nlm.nih.gov]

[…] in vitamin D metabolism, and possibly calcitonin excess. [ncbi.nlm.nih.gov]

calcitonin, and hence calcitonin might play a role in the pathogenesis of early neonatal hypocalcemia. [ncbi.nlm.nih.gov]

Chronic Alcoholism

The concept of "structural plasticity" has emerged as a potential mechanism in neurodegenerative and psychiatric diseases such as drug abuse, depression, and dementia. Chronic alcoholism is a progressive neurodegenerative disease while the person continues to abuse alcohol, though clinical and imaging studies show[…] [ncbi.nlm.nih.gov]

Familial Medullary Thyroid Carcinoma

Following successful surgical removal of medullary carcinoma, plasma calcitonin levels gradually decrease into the undetectable range over a period of several weeks. [clinlabnavigator.com]

These included 1 patient whose calcitonin was stable, and 11 patients who had decreasing calcitonin levels. [en.wikipedia.org]

A rise in a previously undetectable or very low postoperative calcitonin level is highly suggestive of disease recurrence. [clinlabnavigator.com]

Osteoporosis

Raloxifene (an estrogen-like drug), bisphosphonate drugs (such as risedronate and alendronate), and calcitonin decrease bone resorption. [britannica.com]

Our treatments may include estrogen replacement therapy for women, calcitonin to decrease bone loss, and bisphosphonates to increase bone mass and reduce the risk for fracture [umms.org]

People may be given calcitonin to decrease the pain caused by vertebral fractures. Exercises to strengthen muscles in the back may help relieve chronic back pain. [msdmanuals.com]

Hypocalcemia

It is caused primarily by precipitation of calcium soaps in the abdominal cavity, but glucagon-stimulated calcitonin release and decreased PTH secretion may play a role. [emedicine.com]

An association with these medicines and an increased risk for hip fractures in elderly patients has been made because of decreased calcium absorption. [emedicine.com]

Other medication effects that may lead to hypocalcemia are as follows: Calcitonin and bisphosphonates cause chelation and end-organ inhibition Ethylene glycol complexes with [emedicine.com]

Fracture

Calcitonin decreases blood calcium levels and helps restore calcium to bone. Calcium is needed in the blood stream to help muscle cells including the heart to function. [medicinenet.com]

Parathyroid hormone increases calcium levels in the bloodstream, meaning, that it regulates it's release by bone and decreasing bone density. [medicinenet.com]

Electrolyte Imbalance

Calcitonin- decreases- serum calcium- inhibit the effect of PTH on osteoclasts and increasing urinary calcium excretion. [slideshare.net]

The levels of calcium in the body are managed by calcitonin which decreases calcium levels and parathyroid hormone which increases the calcium levels. [registerednursing.org]

Calcium levels are controlled by calcitonin, which promotes bone growth and decreases calcium levels in the blood, and parathyroid hormone, which does the opposite. [emedicinehealth.com]

Senile Osteoporosis

calcium, estrogen, & calcitonin act by decreasing bone resorption. - calcitonin may act directly on osteoclasts, which do have calcitonin receptors. - calcitonin has recently [wheelessonline.com]

- estrogen : - calcium, estrogen, & calcitonin act by decreasing bone resorption ; - calcium & estrogen act mainly by decreasing activation of new bone remodeling units [wheelessonline.com]

[…] act by decreasing bone resorption; - calcium & estrogen act mainly by decr activation of new bone-remodeling units (not by decr action of existing osteoclasts ); - national [wheelessonline.com]

Healing Fracture

Calcitonin decreases blood calcium levels and helps restore calcium to bone. Calcium is needed in the blood stream to help muscle cells including the heart to function. [medicinenet.com]

Parathyroid hormone increases calcium levels in the bloodstream, meaning, that it regulates it's release by bone and decreasing bone density. [medicinenet.com]

Hereditary Hypophosphatemic Rickets with Hypercalciuria

FGF23 secretion via calcitonin; and stimulation of FGF23 catabolism (via enhancement of subtilisin protein convertase activity). [endocrine-abstracts.org]

Novel approaches include targeted inhibition of FGF23 action with neutralizing antibodies to FGF23, and with the inactive, receptor binding C-terminus of FGF23; decreasing [endocrine-abstracts.org]

Primary Hypomagnesemia with Secondary Hypocalcemia

Controlled by anterior pituitary lobe TSH T 3 more effective, T 4 more abundant Calcitonin: Function: decrease blood calcium levels and blood phosphate levels (by helping [slideplayer.com]

T3 and T4: Calcitonin: • Function: metabolism regulation • Function: decrease blood (break down carbohydrates and calcium levels and blood fats, synthesize proteins) phosphate [studyslide.com]

[…] nonsteroid hormones • Triiodothyronine (T3) • Thyroxine (T4) – Regulates metabolism • increases protein synthesis • promotes glycolysis, gluconeogenesis, glucose uptake • Calcitonin [studyslide.com]

Thyroid Gland Disorder

Calcitonin is released by the thyroid gland if the amount of calcium in the bloodstream is high. Calcitonin decreases the amount of calcium and phosphorus in the blood. [patient.info]

When the calcium level is high in the bloodstream, the thyroid gland releases calcitonin. Calcitonin slows down the activity of the osteoclasts found in bone. [patient.info]

This decreases blood calcium levels. When calcium levels decrease, this stimulates the parathyroid gland to release parathyroid hormone. [patient.info]

Multiple Endocrine Neoplasia Type 2B

However, the values of serum calcitonin and CEA did not decrease to the normal ranges. [ncbi.nlm.nih.gov]

The decrease in calcitonin from baseline was 59 (35–84)% during cycle 1. [clincancerres.aacrjournals.org]

0002251 Autosomal dominant inheritance 0000006 Colonic diverticula 0002253 Constipation 0002019 Diarrhea Watery stool 0002014 Disproportionate tall stature 0001519 Elevated calcitonin [rarediseases.info.nih.gov]

Achlorhydria

Suppression of endogenous gastrin secretion in 5 of the patients by intragastric acid administration was not accompanined by any decrease in calcitonin concentration in serum [ncbi.nlm.nih.gov]

Neonatal Severe Hyperparathyroidism

Hydration, forced diuresis, calcitonin, bisphosphonates and cinacalcet have been used to lower serum Ca prior to surgery. [abstracts.eurospe.org]

Unfortunately, serum calcium concentration did not drop significantly (serum Ca decreased to 27 mg/dL after treatment). [theijcp.org]

Other measures to decrease reabsorption of bone include the bisphosphonates pamidronate and zoledronate, salmon calcitonin, and plicamycin. 9 General anaesthesia is most commonly [jpma.org.pk]

Spinocerebellar Ataxia Type 10

[…] estrogen > more osteoclasts > more resorption Treat- bisphosphonates, teriparatide, SERMS, calcitonin, denosumab decreased bone resoption- not a good acidic environment [quizlet.com]

[…] pregnancy MAO inhibitor patients who eat cheese overuse of secondary ossification center of tibial tuberosity activating mutation of FGFR3- blocks chondrocyte proliferation Decreased [quizlet.com]

Lumbar Compression Fracture

[…] can be used for four weeks to decrease pain medical management can consist of bisphosphonates to prevent future risk of fragility fractures some patients may benefit from [orthobullets.com]

This has the additional benefit of decreasing the pain of compression fractures. You can also take calcium and vitamin D supplements. [paindoctor.com]

[…] observation and gradual return to activity PLL intact (even if > 30 degrees kyphosis or > 50% loss of vertebral body height) technique if the fracture is less than five days old calcitonin [orthobullets.com]

Tumor of Endocrine Glands

Calcitonin causes a decrease in the concentration of calcium in the blood. [cancerindex.org]

[…] oxidative metabolism Decreases ECF [Ca 2+ ] TSH from anterior pituitary. [medical-dictionary.thefreedictionary.com]

Calcitonin works with secretions from the parathyroid glands to maintain the balance of calcium necessary for the body to function. [cancerindex.org]

Familial Paget Disease of Bone

These include: Bisphosphonates: These drugs are the first treatment, and they help decrease bone remodeling. [nlm.nih.gov]

Salmon calcitonin has been shown to reduce elevated indices of bone turnover by 50 percent, decrease symptoms of bone pain, reduce warmth over affected bones, improve some [rarediseases.org]

Calcitonin: This hormone is involved in bone metabolism. It may be given as a nasal spray (Miacalcin), or as an injection under the skin (Calcimar or Mithracin). [nlm.nih.gov]

Paget Disease of the Bone

[…] have receptor sites for calcitonin which reduces bone resorption by decreasing both their activity and number and relieves the pain of Pagets in up to 80% of cases Leads [flinders.edu.au]

These include: Bisphosphonates: These drugs are the first treatment, and they help decrease bone remodeling. [nlm.nih.gov]

Polypeptide hormone with 32 aminoacids ® inhibition of osteoclastic resorption, decrease in calcium iron release (A synthetic human like calcitonin is now available) Osteoclasts [flinders.edu.au]

Depressed Skull Fracture

Calcitonin decreases blood calcium levels and helps restore calcium to bone. Calcium is needed in the blood stream to help muscle cells including the heart to function. [medicinenet.com]

Parathyroid hormone increases calcium levels in the bloodstream, meaning, that it regulates it's release by bone and decreasing bone density. [medicinenet.com]

Wrist Fracture

Calcitonin decreases blood calcium levels and helps restore calcium to bone. Calcium is needed in the blood stream to help muscle cells including the heart to function. [medicinenet.com]

Parathyroid hormone increases calcium levels in the bloodstream, meaning, that it regulates it's release by bone and decreasing bone density. [medicinenet.com]