Calcium Decreased: Causes & Reasons

Warning: Do not use in emergencies, if pregnant, if under 18, or as a substitute for a doctor’s advice or diagnosis. Learn more

Possible Causes for Calcium Decreased

Hypocalcemia

[…] albumin to bind with more calcium and thereby decreasing the freely ionized portion of total serum calcium. [en.wikipedia.org]

[…] etc.) 2 ) Increased calcium loss in body fluids : certain diuretics. 3 ) Decreased intestinal absorption : decreased intake; impaired vitamin D metabolism (renal failure) [globalrph.com]

Decreases in serum albumin below 4.0 g/dL decrease total calcium by 0.8 mg/dL for each 1.0 g/dL decrease in serum albumin. [link.springer.com]

Hypoparathyroidism

Decreased PTH levels lead to low calcium levels and high phosphorus levels in the blood. [nichd.nih.gov]

Results also indicated that serum calcium remained stable and 24-hour urinary calcium decreased by 32%. [endocrinologyadvisor.com]

Lab work reveals a decreased serum calcium, decreased parathyroid hormone, and an elevated serum phosphate. On EKG there is a prolongation of the QT interval. [smartypance.com]

Hungry Bones Syndrome

[…] referred to as pseudohypocalcemia, where the total calcium is decreased, but ionized calcium remains unaffected. [symptoma.com]

Since all patients undergoing successful parathyroid surgery will have a decrease in their blood calcium, we must put them on oral calcium so the decrease in their blood calcium [blog.parathyroid.com]

This deficiency may be due to a variety of factors, including: poor calcium intake over a long period of time, especially in childhood medications that may decrease calcium [healthline.com]

Secondary Hypoparathyroidism

low phosphate) Administer Medications: Goal of medications are to increase calcium levels and decrease phosphate levels IV calcium (if severe) Calcium Gluconate Oral calcium [registerednursern.com]

Katsambas et al suggested that the decrease of serum calcium (main decrease is in nonionized fraction with mild decrease in ionized calcium) and vitamin D during pregnancy [casesjournal.biomedcentral.com]

Primary hypoparathyroidism and pseudohypoparathyroidism also result in decreased 24-h excretion of calcium and phosphate. [usmleforum.com]

Hyperphosphatemia

[…] levels in the body—important for cardiac function (when phosphorus increases, calcium decreases, and vice versa) Aid for gastric motility Foods containing phosphorus If you [consultant360.com]

Vitamin D normally works to increase serum calcium levels by increasing dietary calcium absorption and decreasing renal calcium excretion. [prognosisquestions.com]

The decrease of active vitamin D results in decreased intestinal absorption of calcium, decreased renal calcium and phosphate reabsorption, and impaired bone mineralization [ncbi.nlm.nih.gov]

Familial Hypophosphatemia

Milk calcium concentrations were only modestly decreased so that the ratio of calcium to phosphorus was greatly elevated. [ncbi.nlm.nih.gov]

Laboratory testing is significant for a decreased serum calcium and phosphate levels and elevated parathyroid hormone and serum alkaline phosphatase levels. [medbullets.com]

This condition produces decreased calcium and increased phosphorus levels. [drugbank.ca]

Vitamin D Deficiency

Vitamin D deficiency rickets (VDDR) is a disorder biochemically characterized by elevated serum alkaline phosphatase (ALP) activity, normal or decreased serum calcium (Ca) [ncbi.nlm.nih.gov]

Calcium supplementation combined with vitamin D in the last part of the study did not lead to a decrease of biochemical markers of bone turnover. [doi.org]

In stage 2 hypovitaminosis D, there was decreased intestinal calcium absorption and decreased bone mass, as in stage 1, but in biopsies there was identifiable early osteomalacia [doi.org]

Acute Alcohol Intoxication

The serum concentration of ionized calcium reached a nadir eight hours after the beginning of alcohol administration (decreasing from 1.18 +/- 0.01 to 1.15 +/- 0.01 mmol per [ncbi.nlm.nih.gov]

In a manner consistent with the developing hypoparathyroidism, the serum levels of ionized and total calcium decreased and the urinary excretion of calcium increased. [nejm.org]

The serum concentration of ionized calcium decreased from 1.20 +/- 0.01 to 1.16 +/- 0.01 mmol per liter, reaching a nadir 8 to 12 hours after alcohol administration was begun [ncbi.nlm.nih.gov]

Hypomagnesemia

Magnesium is antagonistic to the actions of calcium. Pathogenesis Etiology Decreased intake due to anorexia. [vetstream.com]

This increased cytosolic calcium concentration may be secondary to decreased activation of calcium channels, which may enhance calcium current into cells, decrease calcium [emedicine.com]

[…] efflux from cells, increase cellular permeability to calcium, or decrease sarcoplasmic reticulum reuptake of intracellularly released calcium. [emedicine.com]

Pseudohypoparathyroidism

[…] foods can significantly decrease calcium levels and should be avoided. [healthline.com]

[…] normal phosphate normal vit D decreased vitamin D 3 Type Appearance PTH Calcium Phos Vit D Response to PTH administration Genetics Hypoparathyroidism Normal ↓ ↓ ↑ ↓ - - Pseudohypoparathyroidism [orthobullets.com]

Decreased levels of PTH lead to low levels of calcium and high levels of phosphorus in the blood. [medicinenet.com]

Chronic Kidney Insufficiency

Decreased production of the active form of vitamin D can cause low levels of calcium in the blood. [emedicinehealth.com]

Hypocalcemia develops primarily from decreased intestinal calcium absorption because of low plasma calcitriol levels. [emedicine.medscape.com]

High phosphorus levels and lack of vitamin D cause blood levels of calcium to decrease, causing activation of the parathyroid hormone (PTH). [emedicinehealth.com]

Acute Pancreatitis

Between one and three months postpartum, her serum calcium decreased from 11.4 to 10.2 mg/dL while her 1,25(OH) 2 D level decreased from 83 to 24 pg/mL. [ncbi.nlm.nih.gov]

– BUN increase – Serum calcium – Base deficit – Fluid sequestration – PaO2 – AST = aspartate aminotransferase; BUN = blood urea nitrogen; PaO2 = partial arterial oxygen tension [arupconsult.com]

If the lipase level is about 2.5 to 3 times that of amylase, it is an indication of pancreatitis due to alcohol.[13] Decreased serum calcium Glycosuria Regarding selection [en.wikipedia.org]

Proximal Renal Tubular Acidosis

[…] excretion with profound acidosis Increased Normal Decreased K excretion Increased Increased Decreased Calcium excretion Increased Normal to increased Normal (?) [netscut.templaro.com]

[…] serum calcium and increased parathyroid hormone levels associated with Vitamin D deficiency probably reduce the bicarbonate reabsorption at the proximal tubules of kidney [sjkdt.org]

[…] reabsorption and thus decrease the risk of nephrocalcinosis. [amboss.com]

Acute Kidney Injury

Decreased blood flow to the kidney, such as from hypercalcemia (high blood calcium level) or severe heart disease A disease or condition that affects the kidneys, such as [drugs.com]

Decreased creatinine clearance may indicate decreased kidney function. [labtestsonline.org]

[…] managing calcium and phosphate metabolism in addition to playing a role in cell kidney, cardiac, and immune system functions. [labtestsonline.org]

Malabsorption Syndrome

[…] serum level of calcium is a safe and cost-effective treatment in such a parathyroid hormone-deficient hypoparathyroid patient with malabsorption syndrome. [ncbi.nlm.nih.gov]

[…] fat, carbohydrate, and protein absorption; weight may be 80-90% of usual weight despite increased oral intake of nutrients muscle cramping due to decreased vitamin D, calcium [encyclopedia.com]

Muscle cramp from decreased vitamin D, calcium absorption. [en.wikipedia.org]

Renal Tubular Acidosis

[…] excretion with profound acidosis Increased Normal Decreased K excretion Increased Increased Decreased Calcium excretion Increased Normal to increased Normal (?) [netscut.templaro.com]

Carpopedal spasm developed during the recovery period because of decreased lionized calcium secondary to alkali therapy which resolved on calcium administration. [jpma.org.pk]

[…] alertness Fatigue Impaired growth in children Increased breathing rate Kidney stones Nephrocalcinosis (too much calcium deposited in the kidneys) Osteomalacia (softening [mountsinai.org]

Small-Cell Carcinoma of the Lung

Other symptoms include fractures, constipation or decreased alertness due to high calcium levels. [cancercenter.com]

Celiac Disease

[…] albumin level Malnutrition Elevated calcium level, decreased phosphate level Vitamin D deficiency, secondary hyperparathyroidism Thrombocytosis, leukocytosis General inflammatory [aafp.org]

Since the diagnosis of celiac disease is often delayed, there can be significant issues with iron deficiency anemia, osteoporosis because of decreased levels of calcium and [medicinenet.com]

[…] phosphatase level Osteoporosis, osteomalacia Elevated aspartate transaminase and alanine transaminase levels Minimal elevation common in celiac disease; presumably autoimmune Decreased [aafp.org]

Kidney Disease

[…] consumption Cutting back carbohydrates for those with diabetes Decreasing saturated fats to help lower cholesterol Lowering sodium for people with high blood pressure or [davita.com]

Decreased production of the active form of vitamin D can cause low levels of calcium in the blood. [emedicinehealth.com]

[…] fluid retention by cutting out processed and pre-packaged foods Limiting calcium if blood levels are too high Taking water soluble vitamins such as C (100 mg per day) and [davita.com]

Renal Tubular Acidosis Type 1

[…] reabsorption and thus decrease the risk of nephrocalcinosis. [amboss.com]

[…] alertness Fatigue Impaired growth in children Increased breathing rate Kidney stones Nephrocalcinosis (too much calcium deposited in the kidneys) Osteomalacia (softening [ufhealth.org]

Calcitriol ( 1,25-dihydroxyvitamin D ) substitution Complications of treatment: hyperparathyroidism, nephrocalcinosis Amiloride and hydrochlorothiazide are used to increase calcium [amboss.com]

Anorexia Nervosa

These factors include hypercortisolism, decreased calcium and phosphate intake, decreased muscle mass, progesterone (which promotes bone formation) deficiency and low concentrations [obgyn.onlinelibrary.wiley.com]

[…] are a risk for bone fractures if taken for two or more years, due to decreased absorption of calcium in the stomach.[55] Medical disorders[edit] The body regulates calcium [en.wikipedia.org]

They may not get enough calcium in their diet or absorb enough of it. How can I help prevent anorexia nervosa in my child? Experts don’t know how to prevent anorexia. [stanfordchildrens.org]

Nephrotic Syndrome

Decreased serum Calcium levels can occur and hyperparathyroidism may develop. May develop osteitis fibrosis and osteomalacia. [pedemmorsels.com]

As vitamin D regulates the amount of calcium present in the blood, a decrease in its concentration will lead to a decrease in blood calcium levels. [en.wikipedia.org]

Blood samples show decreased albumin levels usually less than 2.0 mg/dL and elevated triglyceride and cholesterol levels. [hawaii.edu]

Pancreatic Insufficiency

Lack of vitamin D leads to a diminished intestinal absorption of calcium and phosphate leading to bones weakening, hyperparathyroidism, osteopenia and osteoporosis. [medcraveonline.com]

[…] assimilation, patients cannot benefit from fat-soluble vitamins intake and suffer marked hypo vitamin sis. [3] Vitamin A deficiency provokes visual disturbances such as an overall decreased [medcraveonline.com]

Ulcerative Colitis

A diet free of dairy products may decrease symptoms and is worth trying but does not need to be continued if no benefit is noted. [msdmanuals.com]

All people who have ulcerative colitis should take calcium and vitamin D supplements. Small doses of loperamide are taken for relatively mild diarrhea. [msdmanuals.com]

Short Bowel Syndrome

For mid and long term, osteoporosis due to calcium and Vitamin D malabsorption, kidney stones, increase of acid production in the stomach and decrease in gastric time leads [gastrohealth.com]

• Unabsorbed fatty acid binds calcium more than oxalate. 12. 5. [slideshare.net]

Supplementation: vitamins such as B12, A, D, E, K and minerals, potassium, chloride, magnesium, calcium, zinc, iron and selenium. [gastrohealth.com]

Childhood Celiac Disease

Failure to do so may result in malnutrition, decreased bone density due to calcium loss, miscarriages or infertility, lactose intolerance and certain types of cancer. [boystownhospital.org]

Calcium and vitamin D malabsorption (and compensatory secondary hyperparathyroidism ) may cause osteopenia (decreased mineral content of the bone) or osteoporosis (bone weakening [en.wikipedia.org]

[…] and vitamin D may be another clinical feature of celiac disease leading to decreased bone mass, particularly in elderly patients who are already susceptible to metabolic [ncbi.nlm.nih.gov]

Cystic Fibrosis

Abnormalities of calcium metabolism independent of vitamin D status have been reported ( Greer 2003 ). [dx.doi.org]

Many of these factors are inter‐related (e.g. pancreatic exocrine insufficiency contributing to malabsorption of vitamin D, exacerbated by decreased sun exposure if indoors [doi.org]

The pathophysiology of the observed imbalance of increased bone resorption and decreased bone formation has not been clearly delineated ( Boyle 2006 ). [dx.doi.org]

Protein-Losing Enteropathy

Overall, hypoalbuminemia had the best sensitivity and specificity, followed by decreased plasma calcium levels and 24-hour urine protein levels. [journals.plos.org]

In addition, heparin may enhance perivascular protein reabsorption into the lymphatic system. c) Calcium: in 2004, Kim 48 prescribed calcium alone, with no steroids or heparin [scielo.br]

[…] use of exogenous heparin, particularly high molecular weight heparin, may stabilize interactions in the capillary endothelium and the intestinal mucosa, with a consequent decrease [scielo.br]

DiGeorge Syndrome

decreases serum ionized calcium resulting in seizures which may be masked due to muscle relaxants intra operatively but become evident during recovery. [casereports.in]

[…] levels 0002901 Hypoparathyroidism Decreased parathyroid hormone secretion 0000829 Impaired T cell function T-cell dysfunction 0005435 Intellectual disability, mild Mental [rarediseases.info.nih.gov]

Calcium: Children with 22q Deletion Syndrome may have decreased calcium levels. [sickkids.ca]

Syndrome of Inappropriate Antidiuretic Hormone Secretion

[…] with coadministration of antacids containing aluminum, calcium, magnesium, iron, or bismuth subsalicylate; may increase hypoprothrombinemic effects of anticoagulants (monitor [razianesth.freeservers.com]

[…] prothrombin activity); coadministration with oral contraceptives, may decrease effects of oral contraceptives, causing breakthrough bleeding, and increased risk of pregnancy [razianesth.freeservers.com]

>8 years: 6-15 mg/kg/d PO divided bid Contraindications Documented hypersensitivity; severe renal disease; lactation; avoid in children Interactions Bioavailability may decrease [razianesth.freeservers.com]