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1,717 Possible Causes for Cardiac Signs and Symptoms, Most Patients Have Adult Onset of Symptoms, Mutation in the CALM2 Gene

  • Glycogen Storage Disease due to Muscle Phosphorylase Kinase Deficiency

    The onset of symptoms can occur in childhood or adulthood; most patients have adult onset.[rarediseases.org] Sudden death from cardiac arrest can occur in childhood or adolescence in people with muscle GSD 0.Individuals with liver GSD 0 usually show signs and symptoms of the disorder[icdlist.com] There are autosomal recessive forms of GSD IX (caused by mutations in PHKB, PHKG1, PHKG2, CALM1, CALM2, and CALM3 ), a X-linked liver form (caused by mutations in PHKA2 ),[bmcmedgenet.biomedcentral.com]

  • Long QT Syndrome

    Most people who experience sudden cardiac arrest die. In about 1 out of 10 patients, sudden cardiac arrest or death is the first sign of LQTS.[daviddarling.info] RESULTS: A novel de novo CALM2 mutation (D132H) was discovered by candidate gene screening in a male infant with prenatal bradycardia born to healthy parents.[ncbi.nlm.nih.gov] Primary care physicians have an opportunity to recognize the occasional patient with a family history or premonitory signs and symptoms of SADS, allowing for the initiation[aafp.org]

    Missing: Most Patients Have Adult Onset of Symptoms
  • Ventricular Arrhythmia

    The patient does not have any serious signs or symptoms as a result of the increased heart rate.[acls.net] LQT15LQT15 is caused by heterozygous mutations in the CALM2 (Calmodulin 2) gene (114182) on chromosome 2p21.[en.wikipedia.org] Signs and symptoms Edit Ventricular fibrillation is a cause of cardiac arrest.[en.m.wikipedia.org]

    Missing: Most Patients Have Adult Onset of Symptoms
  • Anemia

    Laboratory Tests Hemolytic anemias are often first identified by signs and symptoms, during physical examination, and by medical history.[labtestsonline.org] A medical history can reveal, for example, a recent transfusion, treatment with penicillin, or cardiac surgery.[labtestsonline.org]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Acute Hyperventilation

    Other symptoms are lightheadedness, dizziness, peripheral paresthesia, tingling of the hands and feet, muscle weakness, tetany, and cardiac arrhythmia.[medical-dictionary.thefreedictionary.com] See also metabolic acidosis, respiratory acidosis. observations Deep and rapid breathing at rates as high as 40 breaths per minute is a major sign of respiratory alkalosis[medical-dictionary.thefreedictionary.com]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Hypoglycemia

    A 61-year-old woman with multiple metastatic and unresectable gastrointestinal stromal tumors (GISTs) was referred for investigation of refractory hypoglycemia that developed four months before this hospitalization. On admission, her fasting plasma glucose was 38 mg/dL despite 10% glucose infusion. Investigations[…][ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Substance Abuse Problems

    Abstract Hospital-wide rumors and anecdotal reports had suggested that there was a potentially serious problem of alcohol and drug abuse among the psychiatric patients of this hospital. The authors describe a systematic, evaluative approach which gave direct and detailed information on the nature and extent of[…][ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Hyperkalemia

    Signs and symptoms Patients with hyperkalemia may be asymptomatic, or they may report the following symptoms (cardiac and neurologic symptoms predominate): Generalized fatigue[emedicine.com] Weakness Paresthesias Paralysis Palpitations Evaluation of vital signs is essential for determining the patient’s hemodynamic stability and the presence of cardiac arrhythmias[emedicine.com]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Third Trimester Pregnancy

    The concomitant phenomenon of a third trimester pregnancy with a significant degree of pelvic organ prolapse is extremely rare. We report on a patient with pelvic organ prolapse complicating third trimester pregnancy treated by concomitant cesarean hysterectomy and abdominal sacrocolpopexy. A 30-year-old woman,[…][ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Cardiac Arrhythmia

    The signs and symptoms of cardiac arrhythmias can range from completely asymptomatic to loss of consciousness or sudden cardiac death.[healthguidance.org] In many instances, cardiac arrhythmia may not produce any signs or symptoms.[symptoma.com] Cardiac arrhythmias are disturbances in the normal rhythm of the heartbeat. Arrhythmias may be a sign of heart disease and can lead to other cardiac symptoms.[medstarunionmemorial.org]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene