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11 Possible Causes for Cardiomegaly on Chest X-ray, Drug-induced Cardiomyopathy, Pulsus Alternans

  • Congestive Heart Failure

    Chest X-ray revealed cardiomegaly, and echocardiogram showed dilated left ventricular (LV) cavity and diffuse hypokinesis with extremely decreased ejection fraction (EF).[ncbi.nlm.nih.gov] Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info]

  • Heart Failure

    Testing may include a chest x-ray to look for cardiomegaly (an enlarged heart), pulmonary edema (fluid in the lungs), or pleural effusion (collection of fluid around the lungs[jama.ama-assn.org] Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info]

  • Dilated Cardiomyopathy

    […] on chest X-ray ( Figure 1 B).[revportcardiol.org] Toxins-induced cardiomyopathy – the most common toxin is ethanol following by illegal drug abuse of cocaine and amphetamines.[escardio.org] Pulsus alternans is an infrequent, complex pathophysiologic sign often associated with severe heart failure.[ncbi.nlm.nih.gov]

  • Myocardial Infarction

    Find out more Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?[eurheartj.oxfordjournals.org] Full text article Definition of hidden drug cardiotoxicity: paradigm change in cardiac safety testing and its clinical implications Full text article Febuxostat for Cerebral[eurheartj.oxfordjournals.org]

  • Alcoholic Cardiomyopathy

    Blood tests will show signs of liver injury and confirm alcohol abuse, while chest X-ray shows pulmonary congestion, cardiomegaly and pleural effusions.[radcliffecardiology.com] Models, Animal Ethanol/toxicity Gene Expression Regulation/drug effects Heart Failure/chemically induced Heart Failure/genetics* Heart Failure/pathology Humans Mice Mitochondria[ncbi.nlm.nih.gov] Leg elevation promptly reversed the pulsus alternans, and the echocardiographic abnormality.[ncbi.nlm.nih.gov]

  • Acute Myocarditis

    Diagnostic Modalities The chest x-ray typically demonstrates cardiomegaly and increased pulmonary vascular markings, indicating pulmonary oedema.[jpma.org.pk] Drug-induced hypersensitivity syndrome due to mexiletine associated with human herpes virus 6 and cytomegalovirus reactivation.[scielo.br] Transformation of myocarditis and inflammatory cardiomyopathy to idiopathic dilated cardiomyopathy: facts and fiction.[scielo.br]

  • Hypersensitivity Myocarditis

    […] on chest x-ray." 20 Diagnostic Evaluation Electrocardiogram (ECG).[ahcmedia.com] A prompt diagnosis, immediate withdrawal of the offending drug and immunosuppressant therapy may decrease mortality in drug-induced acute EM [ 1 ].[karger.com] Diagnostic Modalities The chest x-ray typically demonstrates cardiomegaly and increased pulmonary vascular markings, indicating pulmonary oedema.[jpma.org.pk]

  • Toxic Myocarditis

    Diagnostic Modalities The chest x-ray typically demonstrates cardiomegaly and increased pulmonary vascular markings, indicating pulmonary oedema.[jpma.org.pk] Viruses account for most cases of myocarditis or inflammatory cardiomyopathy, which could induce an immune response causing inflammation even when the pathogen has been cleared[revespcardiol.org] Other etiologic agents responsible for myocarditis include drugs, toxic substances, or autoimmune conditions.[revespcardiol.org]

  • Lymphocytic Myocarditis

    Viruses account for most cases of myocarditis or inflammatory cardiomyopathy, which could induce an immune response causing inflammation even when the pathogen has been cleared[revespcardiol.org] Other etiologic agents responsible for myocarditis include drugs, toxic substances, or autoimmune conditions.[revespcardiol.org]

  • High Output Heart Failure

    The chest X-ray showed cardiomegaly and dilatation of the pulmonary artery.[ncbi.nlm.nih.gov] […] an alcoholic cardiomyopathy.[emedicine.medscape.com] alternans (alternating large and small pulse pressures) and a raised JVP.[patient.info]