Cardiomyopathy & Electromyogram Abnormal & Progressive Contractures: Causes & Reasons

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Cardiomyopathy, Electromyogram Abnormal, Progressive Contractures,

Negated

None

Unsure

None

Possible Causes

Muscular Dystrophy

A pilot study was conducted to assess the safety and efficacy of tranilast in muscular dystrophy patients with cardiomyopathy. [ncbi.nlm.nih.gov]

In DMD and some cases of BMD there is progressive weakness, contractures and the inability to walk. [healthengine.com.au]

Although dilated cardiomyopathy is a sign of Duchenne and Becker muscular dystrophy (described above), X-linked dilated cardiomyopathy is typically not associated with weakness [ghr.nlm.nih.gov]

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Duchenne Muscular Dystrophy

She was treated for peripartum cardiomyopathy (PPCM) with angiotensin converting enzyme inhibitors (ACEi), beta-blockers and diuretics with normalisation of her cardiac function [ncbi.nlm.nih.gov]

Surgical Treatment Progressive contractures may be improved with tendon lengthening but recurrence rates may be high. [posna.org]

BACKGROUND: Duchenne muscular dystrophy (DMD) is frequently complicated by development of a cardiomyopathy. [ncbi.nlm.nih.gov]

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Limb-Girdle Muscular Dystrophy

This is the first report showing the electron microscopic findings of dilated cardiomyopathy (DCM) accompanied with limb girdle muscular dystrophy. [ncbi.nlm.nih.gov]

There is variable rate of progression. May develop myalgia, myoglobinuria, contractures, muscle hypertrophy. [patient.info]

This may manifest as hypertrophic/dilated cardiomyopathy and cardiac dysrhythmias. [circheartfailure.ahajournals.org]

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Becker Muscular Dystrophy

[…] changes in the structure of the muscle cells Tests that stain the muscle sample can be used to visualize any muscle proteins present Electromyogram (EMG): Another diagnostic [dovemed.com]

Patients with Becker muscular dystrophy-related cardiomyopathy typically survive into their 30s, when they succumb to complications of cardiomyopathy or receive heart transplants [ncbi.nlm.nih.gov]

Progressive scoliosis and contracture formation may require surgical intervention. [emedicine.medscape.com]

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Dermatomyositis

(EMG) which can demonstrate abnormal electrical activity in muscles and help distinguish weakness due to muscle disease from weakness due to nerve problems A nerve conduction [mda.org.au]

[…] due to dermatomyositis Dilated cardiomyopathy secondary to dermatomyositis Disorder of respiratory system due to dermatomyositis Juvenile dermatomyositis Juvenile dermatomyositis [icd9data.com]

the muscles begin to waste away (atrophy) and permanently shorten (contracture); children with juvenile dermatomyositis may experience a more rapid onset. [myositis.org.au]

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Facioscapulohumeral Muscular Dystrophy

This is the first report of an FSHD patient with biopsy-proven cardiomyopathy. [ncbi.nlm.nih.gov]

In addition, even within early-onset facioscapulohumeral muscular dystrophy type 1 phenotypes, some cases had uncommon features (head drop, early disabling contractures, progressive [ncbi.nlm.nih.gov]

Progression of disease varies with inability to walk usually taking place at about 20 to 30 years of onset. Facial weakness and contractures may occur later. [icd9data.com]

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Myotonic Dystrophy

Moreover, morphological and functional changes indicative of subclinical cardiomyopathy have been demonstrated by means of cardiac magnetic resonance imaging (CMRI) and spectroscopy [ncbi.nlm.nih.gov]

Shortening of muscles or tendons around joints (contractures). Contractures can further limit mobility. Breathing problems. [mayoclinic.org]

Sottoclasse di myotonic disease, cardiomiopatia ipertrofica, sindrome cerebrale organica, blefaroptosi, myopathy with eye involvement, syndrome associated with hypertrophic cardiomyopathy [commons.wikimedia.org]

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Secondary Myopathy

Although changes seen on electromyography are not pathognomonic for any specific disease process, an abnormal electromyogram can indicate if a neuropathy or neuromuscular [aafp.org]

There are four types of non-ischemic cardiomyopathy: Dilated Cardiomyopathy Hypertrophic Cardiomyopathy Restrictive Cardiomyopathy Arrhythmogenic Right Ventricular Dysplasia [my.clevelandclinic.org]

Progressive contractures in hands, elbow, ankles and knees is progressive and patients usually do not attain ambulation. EOM and facial muscles are spared. [sites.google.com]

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Myopathy

Electroencephalographic abnormalities have been noted in several patients with the early-onset form of the disease before clinically apparent seizure activity begins. [anesthesiology.pubs.asahq.org]

( I25.5 ) peripartum cardiomyopathy ( O90.3 ) ventricular hypertrophy ( I51.7 ) Cardiomyopathy Approximate Synonyms Cardiomyopathy Cardiomyopathy (disease of heart muscle [icd10data.com]

Nevertheless, it is our experience that weakness is slowly progressive while contractures remain virtually constant in adulthood. [academic.oup.com]

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Drug-induced Myopathy

electromyogram and imaging studies revealing areas of edema and inflammation. [readbyqxmd.com]

In some cases, the pathology extends to involve cardiac muscle fibers, resulting in a hypertrophic or dilated cardiomyopathy. [clevelandclinicmeded.com]

Associated problems include tendon and muscle contractures, progressive kyphoscoliosis, impaired pulmonary function, cardiomyopathy, and intellectual impairment. [accessmedicine.mhmedical.com]

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Nemaline Myopathy Type 5

Neuropathy Atrophy Stiffness Myoglobinuria Other features History Physical Examination Laboratory Findings Creatine Kinase Muscle Biopsy Electromyogram Endocrine Cushing's [wikidoc.org]

ACTA1 childhood onset dilated cardiomyopathy nemaline myopathy neuromuscular diseases school-aged child Abbreviations: DCM — dilated cardiomyopathy HCM — hypertrophic cardiomyopathy [pediatrics.aappublications.org]

contractures. [institut-myologie.org]

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Dilated Cardiomyopathy

electromyogram and muscle microscopy. [path.upmc.edu]

Dilated cardiomyopathy is characterized by increased ventricular size and impaired ventricular function. It is the most common form of non-ischemic cardiomyopathy. [symptoma.com]

skeletal myopathy and wasting EMD, LMNA Myotonic dystrophy Myotonia, weakness, baldness and cataracts ZNF9, DMPK1 Duchenne/Becker Progressive X-linked proximal myopathy [ahajournals.org]

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Erb Muscular Dystrophy

Electromyogram shows abnormal muscle movements. [quizlet.com]

[…] insufficiency MedLine Citation: PMID: 6706057 Owner: NLM Status: MEDLINE Abstract/OtherAbstract: We describe a case of Erb's limb girdle muscular dystrophy with congestive cardiomyopathy [biomedsearch.com]

progression. [checkorphan.org]

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Oculopharyngeal Muscular Dystrophy

Cardiomyopathy or cardiac conduction defects have not been reported frequently. [n.neurology.org]

After prolonged rest Fatigue Back pain Tremor (60%) Joint contractures Distal arthrogryposis Normalize with development Course Childhood: Non-progressive; Contractures resolve [neuromuscular.wustl.edu]

Shortening of muscles or tendons around joints (contractures). Contractures can further limit mobility. Breathing problems. [mayoclinic.org]

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Childhood Dermatomyositis

(EMG) which can demonstrate abnormal electrical activity in muscles and help distinguish weakness due to muscle disease from weakness due to nerve problems X-rays of the [mda.org.au]

or ulceration may develop at the sites of these deposits. 40 Calcinosis may resolve over an unpredictable time frame; continued progression of calcifications, on the other [obgynkey.com]

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Progressive Muscular Atrophy

Meier C, Voellmy W, Gertsch M, Zimmermann A, Geissbühler J (1984) Nemaline myopathy appearing in adults as cardiomyopathy. A clinico-pathologic study. [link.springer.com]

Shortening of muscles or tendons around joints (contractures). Contractures can further limit mobility. Breathing problems. [mayoclinic.org]

(see “Pathophysiology”) Contractures in nonaffected regions and scoliosis Inability to walk by approx. 12 years of age Cardiac and respiratory muscle involvement Dilated cardiomyopathy [amboss.com]

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Stiff-Person Syndrome

[…] that may be causing pinched nerves an electromyogram, which can help your doctor evaluate how well the muscles and nerves are working an ultrasound, which can help your doctor [healthline.com]

Patients with cardiomyopathy grade III or IV by the New York Heart Classification will be excluded from this study. Systemic edema or pulmonary edema. [clinicaltrials.gov]

The syndrome began as muscle stiffness in her lower extremities and insidiously progressed to a state of constant stiffness resulting in permanent contractures of her lower [journals.lww.com]

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Muscular Atrophy

An EMG can detect abnormal electrical muscle activity due to diseases and neuromuscular conditions. [texaschildrens.org]

Chaotic atrial tachycardia-induced cardiomyopathy: report of an isolated case. Ann Cardiol Angeiol 2005; 54:292. Yeager Sb, Hougen Tj, Levy Am. [latunisiemedicale.com]

Physical therapists use different therapeutic exercises to help children with SMA improve and maintain mobility, and prevent or slow the progression of contractures and respiratory [moveforwardpt.com]

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Mixed Connective Tissue Disease

Diagnosis of hypertrophic obstructive cardiomyopathy (HOCM) was confirmed by left ventriculography and myocardial biopsy. [ncbi.nlm.nih.gov]

Progressive contracture may result in deformity and loss of function of the hand. [dartmouth-hitchcock.org]

Dupuytren's Contracture : A painless thickening and tightening of tissue beneath the skin on the palm of the hand and fingers. [dartmouth-hitchcock.org]

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Amyotrophic Lateral Sclerosis

Tests to rule out other conditions might include: Electromyogram (EMG). Your doctor inserts a needle electrode through your skin into various muscles. [mayoclinic.org]

We report the case of early recurrence of Tako-Tsubo cardiomyopathy in an elderly woman with amyotrophic lateral sclerosis triggered by different stressors. [ncbi.nlm.nih.gov]

This progressive form begins with weakness, often in the hands and less frequently in the feet or mouth and throat. [merckmanuals.com]

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Glycogen Storage Disease Type 2

[…] and nerve conduction studies are generally both abnormal showing evidence of myopathy (small, short duration motor units) and a mixed pattern of myopathy and neuropathy.28 [nature.com]

lysosomal disease with hypertrophic cardiomyopathy, glycogen storage disease with hypertrophic cardiomyopathy, lysosomal glycogen storage disease Prende il nome da Johannes [commons.wikimedia.org]

Limb contractures in progressive neuromuscular disease and the role of stretching, orthotics, and surgery. [dx.doi.org]

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Glycogen Storage Disease

[…] and nerve conduction studies are generally both abnormal showing evidence of myopathy (small, short duration motor units) and a mixed pattern of myopathy and neuropathy. [nature.com]

We describe a 2-mo-old infant presenting with a familial form of GSD III complicated with cardiomyopathy. [ncbi.nlm.nih.gov]

(40%): Shoulders; Hips; Knees; Neck Weight loss Smooth muscle: Urinary or Fecal incontinence Hearing loss Course Progressive Disability related to disease duration 14 Disability [neuromuscular.wustl.edu]

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Spinal Muscular Atrophy Type 3

EMOTAS study aim to understand if NMJ abnormalities could have an impact on motor performance and fatigue in SMA type 3 ambulatory patients by electromyogram and to improve [clinicaltrials.gov]

Dilated cardiomyopathy in Kugelberg-Welander disease: coexisting sleep disordered breathing and its treatment with continuous positive airway pressure. [emedicine.medscape.com]

[…] for alignment -Joystick modifications -Contracture development 2* prolonged sitting -Progression of scoliosis - High incidence -Surgery for spinal stabilization What are [quizlet.com]

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Motor Neuron Disease

[…] conventional mucopolysaccharidosis caused by enzymatic deficiencies, although there were in some patients other abnormalities such as cerebral hypomyelination, hypertrophic cardiomyopathy [medlink.com]

Arthrogryposis (joint contractures) is seen in some of these cases. At the other end, there are cases that begin in young adult life and have a slow progression. [neuropathology-web.org]

Cardiac Valvular disease, cardiomyopathy, right ventricular dysfunction and congestive heart failure [2, 27]. [hindawi.com]

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Friedreich Ataxia

Electromyogram – Looks for muscle damage. Electrocardiogram – Checks for abnormalities in the heartbeat. [drugs.com]

They may develop a cardiomyopathy (CM) phenotype, which is similar to hypertrophic cardiomyopathy and potentially progresses towards a life-limiting problem. [escardio.org]

Dysphagia is common and progresses with the disease, and in advanced cases patients require modified diets, and eventually nasogastric feeding or gastrostomy. 7 Common oculomotor [academic.oup.com]

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Distal Myopathy Type 3

Neuropathy Atrophy Stiffness Myoglobinuria Other features History Physical Examination Laboratory Findings Creatine Kinase Muscle Biopsy Electromyogram Endocrine Cushing's [wikidoc.org]

Involvement of the heart consists of usually terminal cardiomyopathy. [icd9data.com]

Emery-Dreifuss Muscular Dystrophy: Emery-Dreifuss muscular dystrophy is characterized by the triad of joint contractures, slowly progressive muscle weakness and wasting, and [mayomedicallaboratories.com]

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Myotonia Congenita

The electromyogram tests the electrical impulses from the affected muscles. The abnormal repetitive impulses can confirm this disease. [symptoma.com]

• A 17-year-old boy with Duchenne's muscular dystrophy and congestive cardiomyopathy with a left ventricular thrombus is described. [jamanetwork.com]

[…] atrophy, joint contractures, high serum creatine kinase levels, and conspicuous myopathic changes on muscle histopathology. [ncbi.nlm.nih.gov]

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Congenital Merosin-Positive Muscular Dystrophy

Creatinine phosphokinase (CPK) level was 2451 U/L and electromyogram was suggestive of a myopathic disorder. Brain imaging revealed no abnormality. [neurologyindia.com]

الصفحة 214 - Both hypertrophic and dilated cardiomyopathies are caused by mutation of the same gene, deltasarcoglycan, in hamster: An animal model of disrupted dystrophin-associated [books.google.com]

Progressive scoliosis occurs with onset 4 to 12 years. Contractures of the elbow flexors; hip extensors, ankles, and knees are common. [academlib.com]

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Alcoholic Myopathy

Although changes seen on electromyography are not pathognomonic for any specific disease process, an abnormal electromyogram can indicate if a neuropathy or neuromuscular [aafp.org]

Skip to Content « Previous Page En Español Alcoholic Cardiomyopathy Topic Overview Alcoholic cardiomyopathy is caused by long-term alcohol abuse. [northshore.org]

[…] deformities may be present in addition to slowly progressive weakness. [clevelandclinicmeded.com]

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Nemaline Myopathy

However, the electromyogram (EMG) test results will show abnormalities. A muscle biopsy is done to confirm the diagnosis. [primehealthchannel.com]

The combination of nemaline myopathy and cardiomyopathy is rare, and this is the first reported case of dilated cardiomyopathy associated with childhood-onset nemaline myopathy [ncbi.nlm.nih.gov]

Muscle weakness and contractures can be present early and are progressive. Motor development is delayed and may be limited to rolling from side-to-side. [wohproject.org]

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