Cardiomyopathy & Fever & Iodine-Induced Hyperthyroidism: Causes & Reasons

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Cardiomyopathy, Fever, Iodine-Induced Hyperthyroidism,

Negated

None

Unsure

None

Possible Causes

Graves Disease

[…] disease is an autoimmune disease, which can manifest with a variety of extrathyroidal clinical syndromes like ophthalmopathy, pretibial myxedema (dermopathy), acropathy, cardiomyopathy [ncbi.nlm.nih.gov]

A 61 years old woman presented with low grade fever and weight loss for a month. [ncbi.nlm.nih.gov]

[…] suppressed TSH and elevated serum T3 and T4 levels.1-3 Generally, T3 is higher than T4, which also occurs in toxic multinodular goiter, solitary hyperfunctioning nodule, and iodine-induced [the-hospitalist.org]

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Hyperthyroidism

After appropriate pharmacologic treatment of her hyperthyroidism, she had complete resolution of her cardiomyopathy. [ncbi.nlm.nih.gov]

Familial Mediterranean fever (FMF) is a genetic autoinflammatory disorder characterized by serositis and recurrent fever. [ncbi.nlm.nih.gov]

It suggests that HSG also leads to excessive iodine absorption, which induces secondary hyperthyroidism. [ncbi.nlm.nih.gov]

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Hypothyroidism

Overt hypothyroidism may exacerbate underlying cardiac disease, but cardiomyopathy severe enough to cause heart failure is rare ( Kahaly 2005 ). [doi.org]

Disease features include low grade fever, thyroid pain, dysphagia, and elevated erythrocyte sedimentation rate (ESR). [emedicine.com]

Monitoring of prescription rates of thioamides can be a further tool to detect iodine-induced hyperthyroidism in the general population. [ncbi.nlm.nih.gov]

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Thyrotoxic Heart Disease

Patients presenting with heart failure and dilated cardiomyopathy may have thyrotoxicosis as the underlying cause. [heart.bmj.com]

Common Symptoms of Thyrotoxic Crisis: General symptoms Fever Weight loss and poor feeding habits Profuse sweating Respiratory distress GI symptoms Diarrhea Vomiting Fatigue [hyperthyroidismsymptomsx.com]

It is contraindicated in iodine-induced hyperthyroidism and in patients in whom radioiodine treatment is planned (it causes a reduction of iodine uptake for 6 months). [empendium.com]

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Thyrotoxicosis Factitia

Takotsubo cardiomyopathy in a patient undergoing hemodialysis. [kidney-international.org]

Fever should not be treated with cooling mattresses, and Tylenol is ineffective. [thebigl.co]

[…] thyrotoxicosis Iodine induced hyperthyroidism Iodine-induced hyperthyroidism Iodine-induced thyrotoxicosis Jod Basedow iodine induced hyperthyroidism Thyrotoxicosis due to [icd9data.com]

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Thiamine Deficiency

Alcoholic cardiomyopathy is responsible for 21%–36% of all cases of non-ischaemic dilated cardiomyopathy in Western Society. [oapublishinglondon.com]

[…] motor neuropathy with weakness and hyporeflexia Wernicke encephalopathy altered mental state ophthalmoplegia with horizontal nystagmus ataxia and vestibular dysfunction fever [lifeinthefastlane.com]

However, reports of excessively high levels of iodine have been reported among refugee camps in Africa raising a concern for a risk for iodine-induced hyperthyroidism (IIH [cdc.gov]

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Apathetic Thyrotoxicosis with Thyrotoxic Crisis

(familial) (idiopathic) I42.9 ICD-10-CM Diagnosis Code I42.9 Cardiomyopathy, unspecified 2016 2017 2018 2019 Billable/Specific Code Applicable To Cardiomyopathy (primary) [icd10data.com]

Fever should not be treated with cooling mattresses, and Tylenol is ineffective. [thebigl.co]

[…] with radioactive iodine Subtotal thyroidectomy Self-limited causes of hyperthyroidism, such as subacute thyroiditis, iodine- induced hyperthyroidism, and exogenous administration [slideshare.net]

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T3 Thyrotoxicosis

(familial) (idiopathic) I42.9 ICD-10-CM Diagnosis Code I42.9 Cardiomyopathy, unspecified 2016 2017 2018 2019 Billable/Specific Code Applicable To Cardiomyopathy (primary) [icd10data.com]

Fever should not be treated with cooling mattresses, and Tylenol is ineffective. [thebigl.co]

Iodine-induced hyperthyroidism Some of the causes that regress hyperthyroidism (or worsen thyroid control), despite controlling it during pregnancy include: Stimulation of [hyperthyroidismsymptomsx.com]

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Thyrotoxicosis

These findings suggest a possible role of thyroid-hormone excess in the pathophysiology of some patients who have takotsubo cardiomyopathy. [ncbi.nlm.nih.gov]

Fever is typical and may be higher than 105.8 F (41 C). Patients may present with a true psychosis or a marked deterioration of previously abnormal behavior. [shifrinmd.com]

Jod-Basedow syndrome (iodine-induced hyperthyroidism) is infrequently considered as a cause of thyrotoxicosis, even when typical risk factors are present. [ncbi.nlm.nih.gov]

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Beriberi

In both diseases, cardiac involvement may occur as dilated cardiomyopathy. [ncbi.nlm.nih.gov]

This was defined as the presence of signs of congestive heart failure or shock in the absence of fever or other signs of sepsis, hypovolaemia or cardiac abnormalities, with [ncbi.nlm.nih.gov]

However, reports of excessively high levels of iodine have been reported among refugee camps in Africa raising a concern for a risk for iodine-induced hyperthyroidism (IIH [web.archive.org]

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Dilated Cardiomyopathy Type 1R

1R; CMD1R dilated cardiomyopathy type 1R Left Ventricular Noncompaction 4 CARDIOMYOPATHY, DILATED, 1R Cardiomyopathy, Dilated, type 1R edit Language Label Description Also [wikidata.org]

Symptoms include severe diarrhea, vomiting, fever, and dehydration. Almost all children in the U.S. are likely to be infected with rotavirus before their 5th birthday. [medlineplus.gov]

Amiodarone-induced thyrotoxicosis (AIT) is present in two forms: type 1 AIT, or iodine-induced hyperthyroidism, and type 2 AIT, or destructive thyroiditis. [revespcardiol.org]

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Thyroid Crisis

Myxedema coma with cardiac tamponade and severe cardiomyopathy. Proc 2015; 28: 509-511 32 Mathew V, Misgar RA, Ghosh S et al. [doi.org]

He developed fever and tachycardia, and was diagnosed with thyroid crisis. [ncbi.nlm.nih.gov]

hyperthyroidism (areas of iodine deficiency) Amiodarone Radiocontrast media Metastatic follicular thyroid carcinoma hCG-mediated thyrotoxicosis Hydatidiform mole Metastatic [slideshare.net]

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Hashimoto Thyroiditis

[…] for antibodies) Low FT4, Low TSH (Secondary or Tertiary, TRH stimulation test, MRI)  Treatment Levothyroxine (T4) due to longer half life Treatment prevents bone loss, cardiomyopathy [slideshare.net]

A 47-year-old Filipino woman with a 30-year history of an asymptomatic anterior neck mass developed painful, erythematous annular plaques on her arms with associated fever [ncbi.nlm.nih.gov]

Thyrotoxicosis occurs either as a result of iodine-induced hyperthyroidism itself or secondary to acute destructive thyroiditis (,12). [pubs.rsna.org]

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Agranulocytosis

SELECTED CASES Patient 1 A 60-year-old man with moderately severe congestive heart failure secondary to cardiomyopathy was treated with an experimental inotropic drug, vesnarinone [jamanetwork.com]

Here is the case of a 14-year Thai boy presenting with fever and diarrhea for 3 days. [ncbi.nlm.nih.gov]

Alternative way in patients with hyperthyroidisms is surgery or radioactive iodine which seem to be effective options to restore an euthyroid state. [archbronconeumol.org]

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Renal Cell Carcinoma

Heart problems may include heart failure, heart attack and heart muscle problems (cardiomyopathy) that can lead to death. [sutent.com]

A 58-year-old Chinese male presented with general fatigue and intermittent-remittent fever, accompanied by palpitations and dizziness. [ncbi.nlm.nih.gov]

Iodine-induced hyperthyroidism in a patient with a normal thyroid gland. Postgrad Med J 1986;62(729):661-662. View abstract. Shin, H. C., Kim, S. H., Park, Y., Lee, B. [rxlist.com]

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Carnitine Deficiency

[…] an important cause of cardiomyopathy in humans. [ncbi.nlm.nih.gov]

Abstract A 48-year-old male patient had two episodes of fever, headache, confusion and seizures following an upper respiratory tract infection. [ncbi.nlm.nih.gov]

[…] thyroid abnormalities.[23] In particular, in persons with goiter due to iodine deficiency or with altered thyroid function, a form of hyperthyroidism called Jod-Basedow phenomenon [en.wikipedia.org]

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Iodine-Induced Hyperthyroidism

[…] undergoing coronary imaging and who are at risk for arrhythmias or have limited capacity to deal with the consequences of iodine overload, such as those with heart failure or cardiomyopathy [medpagetoday.com]

Your physician should be contacted if there is yellowing of the skin jaundice, fever, loss of appetite or abdominal pain. [thyroidawareness.com]

Iodine-induced hyperthyroidism has been frequently described when iodine is introduced into an iodine-deficient area. [ncbi.nlm.nih.gov]

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Hypokalemia

Its deficit is associated with cardiomyopathy, retinal degeneration and failure to thrive.7 Metabolic actions include: bile acids conjugation, osmolar regulation, detoxification [revistanefrologia.com]

Moreover, the presence of low grade fever on admission speaks against GBS, as usually patients with GBS had fever days or weeks prior to onset of the symptoms (2,7). [ajns.paans.org]

Additionally, a few case reports have noted a risk for hypokalemia with the use of iodinated contrast. 11 In these cases, iodinated contrast-induced hyperthyroidism leads [ncbi.nlm.nih.gov]

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Hashitoxicosis

[…] syndrome Bulbar palsy Burns Calcium channel blockers Candidiasis Carbohydrates Carcinoid tumor Carcinoma of the penis Cardiac catheterization Cardiac glycosides Cardiac myxoma Cardiomyopathy [amboss.com]

The hallmark symptoms of a thyroid storm is a fever which can go as high as 40.5 - 41.1 C (105 - 106 F). [medhelp.org]

Thyrotoxicosis occurs either as a result of iodine-induced hyperthyroidism itself or secondary to acute destructive thyroiditis (, 12 ). [pubs.rsna.org]

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Selenium Deficiency

A 46-year-old man developed "dilated cardiomyopathy" probably caused by selenium deficiency while on total parenteral nutrition (TPN). [ncbi.nlm.nih.gov]

21705-3523, USA. mharthill@gmail.com Abstract Recently emerged viral infectious diseases (VIDs) include HIV/AIDS, influenzas H5N1 and 2009 H1N1, SARS, and Ebola hemorrhagic fevers [ncbi.nlm.nih.gov]

[Crossref] Dunn JT, Semigran MJ, Delange F (1998) The prevention and management of iodine-induced hyperthyroidism and its cardiac features. Thyroid 8: 101-106. [oatext.com]

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Thyroiditis

Untreated hypothyroidism can lead to an enlarged heart ( cardiomyopathy ), worsening heart failure, and an accumulation of fluid around the lungs ( pleural effusion ) or heart [medicinenet.com]

An 80-year-old Caucasian male presented with fever of 3-week duration. [hindawi.com]

Thyrotoxicosis occurs either as a result of iodine-induced hyperthyroidism itself or secondary to acute destructive thyroiditis (,12). [pubs.rsna.org]

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Myopathy, Endocrine

[…] myopathies and neuropathies, and to include more information on genetic aspects of neuromuscular diseases, quantitative electromyo graphic techniques, plexus and root lesions and cardiomyopathies [books.google.com]

Viral Arthritis 277 14 Infectious Disorders C Lyme Disease 282 14 Infectious Disorders D Mycobacterial Fungal and Parasitic Arthritis 290 14 Infectious Disorders E Rheumatic Fever [books.google.com]

Amiodarone-induced thyrotoxicosis (AIT) is present in two forms: type 1 AIT, or iodine-induced hyperthyroidism, and type 2 AIT, or destructive thyroiditis. [revespcardiol.org]

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Tachyarrhythmia

BACKGROUND: Tachycardia-induced cardiomyopathy is a potentially reversible cardiomyopathy with effective treatment of the tachyarrhythmia. [ncbi.nlm.nih.gov]

Tachycardia is defined as a heart rate more than 100, normal heart rhythm is frequently more than 100 in exercise, excitement, fevers, etc. [healthtap.com]

Two different forms of AIT have to be distinguished: amiodarone induced hyperthyroidism (AIT I) and thyroiditis (AIT II). [medlib.mef.hr]

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Neonatal Graves' Disease

Maternal and fetal outcomes of subsequent pregnancies in women with peripartum cardiomyopathy. N Engl J Med. ‎ [books.google.de]

Thyroid storm is characterized by exaggerated symptoms of hyperthyroidism, such as a very fast heart rate, high fever, diarrhea, agitation, delirium, and/or decreased consciousness [verywell.com]

This is called factitious or iatrogenic hyperthyroidism Amiodarone, an iodinated drug used in heart disease, which can induce both hyperthyroidism and hypothyroidism Lithium [dermnetnz.org]

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Iodine-Induced Hypothyroidism

[…] hyperthyroidism that may occur after a stressful illness in a patient with untreated or undertreated hyperthyroidism and is characterized by delirium, severe tachycardia, fever [aafp.org]

Other beneficial clinical consequences are less severe [iodine-induced hyperthyroidism] and a shorter duration of treatment of [iodine-induced hyperthyroidism], as well as [healio.com]

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Hypergonadotropic Hypogonadism - Partial Alopecia

Defects in LMNA are the cause of cardiomyopathy dilated type 1A (CMD1A) [MIM:115200]. [abcam.cn]

[…] lethal genital anomalies Hemolytic-uremic syndrome Hemophagocytic lymphohistiocytosis Hemophagocytic reticulosis Hemophilia A Hemophilic arthropathy Hemophobia Hemorragic fever [thefullwiki.org]

Hyperthyroidism, Thyroid Storm, and Graves Disease Hypothyroidism Hypothyroidism and Myxedema Coma Iodine Deficiency Lithium-Induced Goiter Medullary Thyroid Carcinoma Myxedema [judarwanto14.wordpress.com]

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Toxic Nodular Goiter

심근병증(Cardiomyopathy in metabolic diseases) 심장 아밀로이드증(Cardiac amyloidosis)(E85.- ) I43.2*영양성 질환에서의 심근병증(Cardiomyopathy in nutritional diseases) 영양성 심근병증(Nutritional cardiomyopathy [dic.impact.pe.kr]

Thyroid crisis may cause: Abdominal pain Decreased mental alertness Fever Immediate hospitalization is necessary. [dxline.info]

Articles with Related Interest: Iodine Induced Hyperthyroidism Making Smarter children with Maternal Iodine Supplements Graves Remission with Iodine Jeffrey Dach MD 7450 Griffin [jeffreydachmd.com]

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Renal Carcinoma

Restrictive cardiomyopathy; Heart failure; Amiloidose; Miocardiopatia hipertrÃ³fica; Miocardiopatia restritiva; InsuficiÃªncia cardÃaca; Keywords: آمیلوئیدوز; Myeloma; Monoclonal [daneshyari.com]

[…] muscles, bones, and joints; itchy skin; diarrhea; nausea; weakness; cough; shortness of breath; constipation; decreased appetite; back pain; upper respiratory tract infection; fever [opdivo.com]

Iodine-induced hyperthyroidism in a patient with a normal thyroid gland. Postgrad Med J 1986;62:661-662. View abstract. Church FC, Meade JB, Treanor RE, and et al. [medlineplus.gov]

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Cardiodysrhythmic Potassium-Sensitive Periodic Paralysis

A family with Andersen-Tawil syndrome and dilated cardiomyopathy. [ncbi.nlm.nih.gov]

Cardiac arrest Sudden cardiac death - Asystole Other Cardiomegaly - Ventricular hypertrophy ( Left, Right / Cor pulmonale ) Heart failure ( Cardiac asthma ) - Rheumatic fever [wikidoc.org]

[1] and amiodarone -induced hyperthyroidism. [2] Mechanism [ edit ] Na /K -ATPase maintains the normal gradients of sodium and potassium between cells and extracellular [en.wikipedia.org]

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Nonendemic Simple Goitre

Chagas Cardiomyopathy. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases, 553-574. [disease.medicclub.info]

Patients may present with 1: sudden onset of abdominal pain right lower quadrant pain and tenderness absence of fever and gastrointestinal symptoms encountered in healthy [radiopaedia.org]

Hyperthyroidism may be precipitated by iodination and cause what is referred to as iodine induced hyperthyroidism (IIH) (33 ; 34 ). [ptolemy.ca]

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