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627 Possible Causes for Cardiomyopathy, T Cell Activation Increased

  • Malnutrition

    Arginase activity Enhanced arginase-induced L-arginine depletion is increasingly recognized as a key mechanism of T cell suppression [ 33 ] and we have shown that increased[journals.plos.org] Carnitine nutritional deficiency Decreased nutritional requirement Deficiency of macronutrients Deficiency of micronutrients Dietary potassium - low Dietary sodium - low Dilated cardiomyopathy[icd9data.com] Explore the full collection Clinical presentation and survival of childhood hypertrophic cardiomyopathy: a retrospective study in United Kingdom Full text article Myocardial[oxfordjournals.org]

  • Toxoplasmosis

    The CNS-IRIS patient showed lower percentage of memory CD4 T cells and higher percentage of activated CD4 T cells at HAART initiation.[ncbi.nlm.nih.gov] GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia , Mol Psychiatry , 2011 , vol. 16 (pg. 1117[doi.org] These results indicate that T. gondii targets activation of pro-apoptotic Bax and Bak to inhibit the apoptogenic function of mitochondria and to increase host-cell viability[ncbi.nlm.nih.gov]

  • Diabetes Mellitus

    A fluorescence activated cell sorting analysis showed an altered T-cell population.[ncbi.nlm.nih.gov] […] was on hemodialysis due to the stage 5 chronic kidney failure and had various comorbid conditions: arterial hypertension, history of acute myocardial infarction, dilative cardiomyopathy[ncbi.nlm.nih.gov] […] that patients with type 1 diabetes or type 2 diabetes are at high risk for several cardiovascular disorders: coronary heart disease, stroke, peripheral arterial disease, cardiomyopathy[circ.ahajournals.org]

  • Stroke

    T-cell activation provides a pathway by which quiescent plaques can be rapidly activated to a symptomatic state. 506 Numerous inflammatory markers are emerging as identifiable[doi.org] We are reporting a case of acute stroke in a young patient with severe ischaemic cardiomyopathy in the absence of traditional risk factors.[ncbi.nlm.nih.gov] BACKGROUND: Stroke is a recognized clinical course of hypertrophic cardiomyopathy.[ncbi.nlm.nih.gov]

  • Hypothyroidism

    Consistent with their playing a fundamental role, an increased proportion of activated T-helper (Th) (CD4 ) cells can be demonstrated in the circulation of a majority of patients[ncbi.nlm.nih.gov] Overt hypothyroidism may exacerbate underlying cardiac disease, but cardiomyopathy severe enough to cause heart failure is rare ( Kahaly 2005 ).[doi.org] The increased inward flux of Na that results from this hormonal action amplifies cell depolarization and may also contribute to activation of membrane Na, K-ATPase or Na [ncbi.nlm.nih.gov]

  • Fabry Disease

    The T/S Fabry patient CD34 cells showed intracellular and secreted α-gal A activities that were increased 3-fold and 18-fold, respectively, compared with the T/NS cells (Fig[ncbi.nlm.nih.gov] KEYWORDS: Fabry disease; cardiomyopathy, hypertrophic; gadolinium; magnetic resonance; mutation; phenotype; stroke[ncbi.nlm.nih.gov] Fabry disease continues to be an important misdiagnosis of hypertrophic cardiomyopathy in a clinical setting.[ncbi.nlm.nih.gov]

  • Aortic Valve Stenosis

    A number of the T cell clones were of CD8 lineage (cytotoxic T cells or natural killer cells), suggesting that these T cells likely participated in the pathogenesis of AVC[doi.org] Numerous clinical maneuvers can be used to distinguish aortic stenosis from the similar-sounding murmurs of hypertrophic obstructive cardiomyopathy and pulmonary valve stenosis[radiopaedia.org] The murmur of hypertrophic cardiomyopathy can also at times mimic the murmur of aortic stenosis.[healio.com]

  • HIV Infection

    […] the vaginas of mice increased numbers of the activated CD4 T cells that are the virus’s primary target, establishing a direct link between the high-risk bacteria and a known[ragoninstitute.org] Female infant with oncocytic cardiomyopathy and microphthalmia with linear skin defects (MLS): a clue to the patho genesis of oncocytic cardiomyopathy?[journals.sagepub.com] HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8 T cell activation, and increased risk[nature.com]

  • Rheumatoid Arthritis

    […] inflammatory cytokines from activated T cells both systemically and locally at the atheroma 33.[doi.org] (0.50–0.66) Cardiac diseases Acute MI 2.6 (0.9) 7.8 (1.3) 0.31 (0.27–0.34) Chronic ischemic heart disease 4.0 (0.9) 11.7 (0.7) 0.32 (0.29–0.35) Congestive heart failure/cardiomyopathy[ncbi.nlm.nih.gov] . • irregular heart rate, • profound bradycardia that required a cardiac pacemaker • Cardiomyopathy. • heart failure. 20. • 1. rapid onset obesity after a 2 year period of[slideshare.net]

  • Eosinophilic Endomyocardial Disease

    […] by T cells ( 201, 202 ).[doi.org] […] and classification of cardiomyopathies and specific heart muscle diseases, respectively.[books.google.de] Specific processes such as sarcoidosis of the heart undoubtedly furnish examples of chronic inflammation as a cause of dilating cardiomyopathy.[books.google.com]

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