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525 Possible Causes for Cartilage Biopsy Abnormal, CD4 Lymphocytes Decreased, Severely Disproportionate Short Stature

  • Cartilage Hair Hypoplasia

    Biopsy shows hypoplasia (underdevelopment) of cartilage to be the nature of the skeletal abnormality. The hair is unusually fine, sparse and light-colored.[medicinenet.com] Of the patients, 57% had a decreased CD4 cell count which led to a decreased total count of T-lymphocytes in 52% and a subnormal CD4 /CD8 cell ratio in 32%.[ncbi.nlm.nih.gov] Suggestive Findings CHH-AD spectrum disorders should be suspected in individuals with: Mild to severe disproportionate short-limbed short stature (final adult height Presence[ncbi.nlm.nih.gov]

  • Chondrodystrophy

    Pseudoachondroplasia usually manifests in the 2 nd year of life with ligamentous laxity and tends to develop severe disproportionate short stature.[doi.org] It’s distinguished by a moderate to severe form of disproportionate short-limb short stature.[en.wikipedia.org] Typically, the growth rate falls below the standard growth curve by approximately age two years, leading to a moderately severe form of disproportionate short-limb short stature[ncbi.nlm.nih.gov]

    Missing: CD4 Lymphocytes Decreased
  • Leri-Weill Dyschondrosteosis

    Abstract Leri-Weill Dyschondrosteosis (LWD; OMIM 127300) is a dominantly inherited skeletal dysplasia characterized by disproportionate short stature with predominantly mesomelic[ncbi.nlm.nih.gov] Predominant and more severe in female (female-to-male ratio 4:1). Stature is short and disproportionate (adult height 135 cm [53.1 inches]).[accessanesthesiology.mhmedical.com] […] clinical form that includes a disproportionately short stature.[frontiersin.org]

    Missing: CD4 Lymphocytes Decreased
  • Schmid Metaphyseal Chondrodysplasia

    The clinical picture is that of a mild achondroplasia and is represented by disproportionate short stature with short limbs but without an obvious rhizomelia, brachydactyly[intechopen.com] Final height is not as severely affected as in achondroplasia and is usually in the range 130–165 cm. 2.1.1.3.[intechopen.com]

    Missing: CD4 Lymphocytes Decreased
  • Ellis-Van Creveld Syndrome

    The syndrome has several typical features: chondrodysplasia resulting in disproportionate short stature, bilateral postaxial polydactyly of the hands, ectodermal dysplasia[jbsr.be]

    Missing: CD4 Lymphocytes Decreased
  • Rheumatoid Arthritis

    To review the diagnostic and prognostic value of anti-mutated citrullinated vimentin (MCV) in rheumatoid arthritis, taking into account the already available serology. Medline was searched via PubMed (1966 to May 2008) for anti-MCV and related terms, arthritis and arthropathies. Studies with anti-MCV,[…][ncbi.nlm.nih.gov]

    Missing: CD4 Lymphocytes Decreased Severely Disproportionate Short Stature
  • Relapsing Polychondritis

    […] in the nose Inflammation of the eye Cartilage damage in the respiratory tract Hearing or balance problems A biopsy of the affected cartilage (most often from the ear) may[merckmanuals.com] A tissue cartilage biopsy can also be conducted which will reveal inflammation in cases of Relapsing Polychondritis. What Are Treatments For Relapsing Polychondritis?[epainassist.com] […] show characteristic abnormalities but is not required for diagnosis.[merckmanuals.com]

    Missing: CD4 Lymphocytes Decreased Severely Disproportionate Short Stature
  • Primary Immune Deficiency Disorder

    The percentage of CD4 T cells is low (about 25% of lymphocytes) and the CD4/C8 ratio is 0.5.[emedicine.medscape.com] In these patients, decreased IL-2 production after T-cell receptor stimulation is also present. A common defect is the response to antigens by CD4 T lymphocytes.[emedicine.medscape.com] This defect is thought to be related to a decreased number and/or function of CD4 T lymphocytes or, occasionally, to an increased number of CD8 T lymphocytes; however, abnormal[emedicine.medscape.com]

    Missing: Cartilage Biopsy Abnormal Severely Disproportionate Short Stature
  • Chondroblastoma

    Chondroblastoma located in the femoral head is one of the locations accounting for frequent recurrence. One of the reasons for this is the difficulty in obtaining appropriate surgical access to it for adequate removal of tumors. The authors present and illustrate a trapdoor procedure for the surgical treatment[…][ncbi.nlm.nih.gov]

    Missing: CD4 Lymphocytes Decreased Severely Disproportionate Short Stature
  • Acquired Immunodeficiency Syndrome

    No side effects such as decreases in white blood cell counts or CD4 lymphocyte levels were seen during S-1 therapy.[ncbi.nlm.nih.gov] Clearly there are multiple causes of CD4( ) T lymphocyte apoptosis in AIDS and therapies that block or decrease that death could have significant clinical benefit.[ncbi.nlm.nih.gov] Clearly there are multiple causes of CD4 T lymphocyte apoptosis in AIDS and therapies that block or decrease that death could have significant clinical benefit.[doi.org]

    Missing: Cartilage Biopsy Abnormal Severely Disproportionate Short Stature