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18 Possible Causes for Cataract, Generalized Motor Seizure, Plasma Fibrinogen Increased

  • Chronic Kidney Insufficiency

    […] taking prednisone for long periods of time, these effects can be significant, including weight gain (especially around the face and trunk), moodiness, sleep disturbances, cataracts[kidshealth.org] In conclusion, the increased risk of thrombosis in patients with renal failure is related to changes in the coagulation cascade with increased levels of fibrinogen and plasma[academic.oup.com] […] levels of plasma fibrinogen, d -dimer and plasminogen activator inhibitor (PAI)-1 [ 62 ].[academic.oup.com]

  • Stroke

    471·3) 461·1 (311·4 to 642·1) 118·0 (114·5 to 121·8) * 35·7 (33·7 to 38·0) * 6·3 (4·3 to 8·7) 6·9 (4·7 to 9·5) 7·0 (4·8 to 9·8) 12·1 (10·4 to 14·0) * 2·1 (0·8 to 3·6) * Cataract[ncbi.nlm.nih.gov] Other biological mechanisms have also been associated with physical activity, including reductions in plasma fibrinogen and platelet activity and elevations in plasma tissue[doi.org] HDL cholesterol, 211,360 reduce platelet aggregation, 361,362 and lower plasma fibrinogen concentration. 363,364 Heavy alcohol consumption can lead to hypertension, hypercoagulability[doi.org]

  • Preeclampsia

    Eclampsia is the occurrence of generalized motor seizures (grand mal seizures) in pregnant women with PE that are not caused by coincident neurological disease and may occur[scielo.br] […] petechiae, blue-berry muffin [purple skin lesions result of dermal erythropoiesis], cardiac defect, hepatosplenomegaly, intracranial calcification, chorioretinitis, and cataracts[doi.org]

  • Systemic Lupus Erythematosus

    The most frequent forms of damage were cataracts (11.9%), and avascular necrosis (unilateral and bilateral combined 10.2%).[ncbi.nlm.nih.gov] Posterior subcapsular cataracts and secondary open-angle glaucoma are common AE of the prolonged GC administration.[ncbi.nlm.nih.gov] Side effects of corticosteroids include weight gain, thinning of the bones and skin, infection, diabetes, facial puffiness, cataracts, and death (necrosis) of the tissues[medicinenet.com]

  • Lupus Encephalitis

    Publicity to a virus through the embryonic stage is able to inflicting psychological retardation, eye cataracts, deafness, urinary, genital, coronary heart, and intestinal[ecigcanadazone.com] Side effects of corticosteroids include weight gain, thinning of the bones and skin, infection, diabetes, facial puffiness, cataracts, and death (necrosis) of the tissues[medicinenet.com] Prednisolone Long term use leads to osteoporsis, a vascular necrosis, HTN, diabetes,…etc cataracts, glucoma, weight gain, myopathy and skin changes, mood changes……..[slideshare.net]

  • Alzheimer Disease

    Shih-Wei Lai, Cheng-Li Lin and Kuan-Fu Liao, Cataract may be a non-memory feature of Alzheimer’s disease in older people, European Journal of Epidemiology, 10.1007/s10654-[doi.org] fibrinogen levels Ramirez-Bosca et al, 2000 Depression : Mice 5,10 mg/kg, p.o Reduce the depressive like behaviour in mice, increase the levels of Serotonin and dopamine[ncbi.nlm.nih.gov] Cataract surgery and age-related cognitive decline: A 13-year follow-up of the English Longitudinal Study of Ageing. PLOS ONE, Vol. 13, Issue. 10, p. e0204833.[dx.doi.org]

  • Liver Failure

    Statin drugs cause liver damage, kidney failure and cataracts, says BMJ 11/7/2010 - Cholesterol-lowering statin drugs significantly increase a person's risk of cataracts,[naturalnews.com] […] is debatable and may even increase bleeding due to the volume load [ 51 ].[intechopen.com] The preoperative INR has no predictive value in relation to intraoperative blood loss and the value of fresh frozen plasma (FFP) administration to correct abnormal INR values[intechopen.com]

  • Metabolic Disease

    Ocular complications often cause severe reduction in visual acuity and can affect any part of the eye including cataract, vitreous degeneration, retinopathy, optic nerve swelling[emedicine.medscape.com] Serum uric acid levels are typically elevated (increasing risk of gout), and a prothrombotic state (with increased levels of fibrinogen and plasminogen activator inhibitor[merckmanuals.com] A prothrombotic state, characterized by increased plasma plasminogen activator inhibitor (PAI)-1 and fibrinogen, also associates with the metabolic syndrome.[circ.ahajournals.org]

  • Homocystinuria

    […] tonic–clonic seizures, and motor aphasia, in addition to coarse facial appearance, mild malar flushing, livedo reticularis on the extremities, and bilateral carotid bruits[advbiores.net] The patient had a past medical history significant for joint hypermobility, arthritis, bilateral cataracts, unilateral hearing loss, anemia, frequent urinary tract infections[ncbi.nlm.nih.gov] […] levels of prothrombotic N -Hcy-fibrinogen. [16] These results provide a possible explanation for the increased atherothrombosis observed in CBS -deficient patients.[emedicine.com]

  • Granulomatous Iritis

    Systemic complications include pulmonary fibrosis, cardiac dysrhythmias, seizures, hydrocephalus, deafness, and motor/sensory deficits from spinal lesions.[eyewiki.aao.org] Posterior subcapsular cataracts may be present if the patient has had repeated episodes of iritis or ongoing chronic inflammation.[emedicine.medscape.com] The most important proteins to effect the rate are fibrinogen, gamma globulin and alpha two globulin. An increase in these proteins will increase the sedimentation rate.[ijo.in]

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