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41 Possible Causes for Cataract, Plasma Fibrinogen Increased, Systemic Amyloidosis

  • Rheumatoid Arthritis

    Finally, amyloidosis is a rare cause of liver involvement in chronic systemic rheumatic diseases [ 15 ].[] Surgically induced scleritis is a rare complication following ophthalmologic surgery such as cataract surgery, pterygium excision, strabismus surgery, and retinal detachment[] Prothrombotic state RA is associated with increased plasma levels of fibrinogen, von Willebrand factor, and plasminogen activator inhibitor 1, producing a prothrombotic state[]

  • Behçet Disease

    Systemic investigation revealed cardiac disfunction with cardiomegaly and progressive renal dysfunction, which indicated the presence of systemic AL-amyloidosis.[] After 3 months of treatment the right eye underwent cataract surgery, after which the protocol was continued.[] Amyloidosis may occur but is very uncommon. Differential diagnosis This depends on which systems are involved.[]

  • Systemic Lupus Erythematosus

    Oct 2016 Familial amyloid polyneuropathy (FAP) is a rare inherited autosomal dominant form of systemic amyloidosis, which classically presents with severe motor, sensory,[] The most frequent forms of damage were cataracts (11.9%), and avascular necrosis (unilateral and bilateral combined 10.2%).[] Posterior subcapsular cataracts and secondary open-angle glaucoma are common AE of the prolonged GC administration.[]

  • Familial Mediterranean Fever

    We presented a case of systemic amyloidosis with FMF, involving the bladder region, myocardium, and renal allograft, diagnosed after renal transplantation.[] Both cataract and glaucoma patients (50%) needed a surgical intervention. In 33.3% of patients, Behçet disease was present as a concurrent disease.[] It can also help prevent a serious complication called systemic amyloidosis. Expectations (prognosis) There is no known cure for familial Mediterranean fever.[]

  • Hodgkin Lymphoma

    […] lymphoma and tumors in the lungs, breasts or gastrointestinal system Vascular disease, including stroke Thyroid dysfunction Sterility Death 12.[] People who undergo radiation or who are on long-term steroid therapy have an increased risk for cataracts.[] Complication Renal amyloidosis followed by contracted kidney and uremia Intoxication Septic complication Cardiovascular disease Second malignancy, such as leukemia, non-Hodgkin's[]

  • Leprosy

    One frequent form of renal involvement is amyloidosis, especially in patients with lepromatous leprosy.[] Either of these leads to: Inability to close the eyelids (lagophthalmos) Keratitis due to exposure, absence of tears, and drying, leading to corneal ulcers Iridocyclitis Cataract[] (Courtesy of Tara Ramachandra) Lagophthalmos, iridocyclitis, corneal ulceration, and/or secondary cataract due to nerve damage and direct bacillary skin or eye invasion 6[]

  • Polymyalgia Rheumatica

    Primary systemic amyloidosis presenting as giant cell arteritis and polymyalgia rheumatica. Arthritis Rheum 1994;37:1621-1626. 53. Behn AR, Perera T, Myles A.[] "Comparator subject had less risk for developing cataracts than patients with PMR, but rates of other comorbidities were similar.[] These include higher blood sugar, weight gain, sleeplessness, osteoporosis (bone loss), cataracts, thinning of the skin and bruising.[]

  • Chronic Kidney Insufficiency

    Diabetes mellitus type 1 or type 2 High blood pressure High cholesterol Heart disease Liver disease Amyloidosis Sickle cell disease Systemic lupus erythematosus Vascular diseases[] […] taking prednisone for long periods of time, these effects can be significant, including weight gain (especially around the face and trunk), moodiness, sleep disturbances, cataracts[] In conclusion, the increased risk of thrombosis in patients with renal failure is related to changes in the coagulation cascade with increased levels of fibrinogen and plasma[]

  • Temporal Arteritis

    Primary systemic amyloidosis presenting as giant cell arteritis and polymyalgia rheumatica.[] However, long term use can lead to complications including high blood pressure, cataracts and glaucoma. In this case, the benefits far out-weigh the risks.[] […] malignancy, systemic infections, dental disease, trigeminal neuralgia, and amyloidosis in the appropriate clinical setting.[]

  • Nephrotic Syndrome

    It occurs in glomerular disease and thrombosis of a renal vein and as a complication of many systemic diseases, diabetes mellitus, amyloidosis, systemic lupus erythematosus[] Caution should be used when prescribing Acthar in patients with diabetes and myasthenia gravis Prolonged use of Acthar may produce cataracts, glaucoma and secondary ocular[] Erythrocyte sedimentation rate is increased due to increased fibrinogen & other plasma contents.[]

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