Catecholamine-Secreting Paraganglioma: Causes & Reasons

Possible Causes for Catecholamine-Secreting Paraganglioma

Hereditary Pheochromocytoma-Paraganglioma

The term pheochromocytoma (PHEO) is applied to catecholamine-secreting paragangliomas of the adrenal gland. [mhmedical.com]

Young AL, Baysal BE, Deb A, Young Jr WF 2002 Familial malignant catecholamine-secreting paraganglioma with prolonged survival associated with mutation in the succinate dehydrogenase [genetics.ouhsc.edu]

A pheochromocytoma, arising from the adrenal medulla, almost always secretes catecholamines, whereas paragangliomas (arising from paravertebral neuroendocrine tissues) can [symptoma.com]

Carotid Body Tumor

The second known case of a malignant catecholamine-secreting (DA)-secreting carotid body paraganglioma is presented. [ncbi.nlm.nih.gov]

(b) 111 In-Octreotide scan showing a catecholamine-secreting carotid body paraganglioma. [edmcasereports.com]

In addition, patients with rare catecholamine-secreting paragangliomas may benefit from additional monitoring by anesthesia during the procedure to control blood pressure [jnis.bmj.com]

Glomus Jugulare Tumor

Catecholamine secreting paragangliomas at the skull base. Skull Base Surg. 1996;6(1):35–45. doi: 10.1055/s-2008-1058911. [ncbi.nlm.nih.gov]

Although every paraganglioma may potentially secrete catecholamines, clinically functioning paragangliomas are only 1-3% as a four to fivefold elevation of serum norepinephrine [jpma.org.pk]

Sympathetic paragangliomas generally secrete catecholamines (epinephrine, norepinephrine) and are usually located in the retroperitoneal space, abdomen, or thorax; paragangliomas [eleccionens.com]

Pheochromocytoma

[…] chain); however, the tumor may develop anywhere in the body "catecholamine-secreting paragangliomas" ("extraadrenal pheochromocytomas"). [emedicine.com]

[…] the adrenal glands in response to stress) Parasympathetic paragangliomas — PGLs that usually do not secrete catecholamines Paragangliomas (PGLs) and pheochromocytomas (PCCs [chop.edu]

Pheochromocytomas and catecholamine-secreting paragangliomas have a similar clinical presentation, but the risk for associated neoplasms, risk for malignancy, and genetic [emedicine.com]

Non-Functioning Paraganglioma

Some of the tumors (named as functional paragangliomas) have been discovered to originate, synthesize, store and secrete catecholamines, which leads to elevated levels of [ncbi.nlm.nih.gov]

Extra-Adrenal Pheochromocytoma

Management of a catecholamine-secreting paraganglioma requiring aortic reconstruction. Vasc Endovascular Surg. 2010 Feb;44(2):150-4. (96.) [revistas.udea.edu.co]

Hypertension and unilateral renal ischemia (Page kidney) due to compression of a retroperitoneal paraganglioma. Am J Nephrol. 1996;16(2):91-4. (95.) [revistas.udea.edu.co]

Vagal Paraganglioma

Approximately 1% to 3% of paragangliomas secrete catecholamines. A fivefold increase in catecholamines is sufficient to produce symptoms. [entokey.com]

Paraganglioma cells commonly secrete hormones known as catecholamines, including adrenaline, which is the fight-or-flight hormone. [mayoclinic.org]

The most common symptoms arise from the compression of its adjacent structures, and only 5% secrete catecholamines like the paragangliomas of the adrenal gland also known [cureus.com]

Labile Hypertension

Most catecholamine-secreting paragangliomas are located in the abdomen and pelvis [ 2 ]. [ 123 I]Metaiodobenzylguanidine (MIBG) scintigraphy is commonly used to localize these [ndt.oxfordjournals.org]

Most catecholamine-secreting paragangliomas are located in the abdomen and pelvis [2]. [123I]Metaiodobenzylguanidine (MIBG) scintigraphy is commonly used to localize these [academic.oup.com]

catecholamines.1, 2 When the tumors arise from chromaffin tissue of the sympathetic ganglia in the thorax or abdomen they are known as paragangliomas or extra adrenal phaeochromocytoma [bioline.org.br]

Hemorrhagic Stroke

To describe a case of multiple catecholamine-secreting paragangliomas, with a hemorrhagic stroke as the main clinical manifestation. [ncbi.nlm.nih.gov]

Sympathetic paragangliomas are rare catecholamine-secreting tumors of extra-adrenal origin, and their diagnosis in children is even more infrequent. [ncbi.nlm.nih.gov]

Iodine I 123 metaiodobenzylguanidine scintigraphy showed high uptake in those same areas, consistent with the diagnosis of multiple catecholamine-secreting paragangliomas. [ncbi.nlm.nih.gov]

Cauda Equina Neoplasm

Paragangliomas arising outside of the skull base and neck are mostly sympathetic and secrete catecholamine, resulting in hyperadrenergic symptoms, including hypertension, [thenerve.net]

A sympathetic ganglion consists of chromaffin cells that can synthesize and secrete catecholamines, including norepinephrine. [thenerve.net]

Before resection, the likelihood of catecholamine secretion should be considered even in cases without hyperadrenergic symptoms. [thenerve.net]

Carney-Stratakis Syndrome

Coupled with his history of poorly controlled hypertension, a catecholamine-secreting paraganglioma was suspected. [imedpub.com]

Glomus Tumors, Familial Nonchromaffin Paragangliomas Pheochromocytomas (PCC) and paragangliomas (PGL) are rare catecholamine-secreting tumors that arise from the chromaffin [centogene.com]

catecholamines. [journals.lww.com]

Carney Triad

paraganglioma. [semanticscholar.org]

Bourke Published 1998 in The European respiratory journal Carney's syndrome consists of a combination of three rare tumours: gastric leiomyosarcoma, pulmonary chondroma and catecholamine-secreting [semanticscholar.org]

Pheochromocytoma-Islet Cell Tumor Syndrome

The clinical manifestations of this disorder consist in thoracic, abdominal, and pelvic catecholamine-secreting paragangliomas, parasympathetic head and neck paragangliomas [intechopen.com]

Of these tumors, catecholamine-secreting neoplasms are termed functioning paraganglioma or extraadrenal pheochromocytoma. [academic.oup.com]

(PCC) and paragangliomas (PGL) are rare catecholamine secreting tumors arising from chromaffin cells of adrenal medulla.[1] PCC/PGL may present as sporadic or familial disease [ncbi.nlm.nih.gov]

Epigastric Hernia

Laparoscopic management of a catecholamine-secreting paraganglioma in a 15-year-old boy We report the case of the surgical removal of a paravesical paraganglioma located on [websurg.com]

Jugular Foramen Syndrome

Matishiak MZ, Symon L, Cheeseman A, et al: Catecholamine-secreting paragangliomas of the base of the skull. J Neurosurg 66:604-608, 1987 21. [slideshare.net]

Schwaber MK, Glasscock ME, Nissen AJ, et al: Diagnosis and manage-ment of catecholamine secreting glomus tumors. Laryngoscope 94: 1008-1015, 1984 22. [slideshare.net]

Cardiomyopathy

BACKGROUND: Paragangliomas are catecholamine-secreting tumors of the paraganglia. [ncbi.nlm.nih.gov]

The literatures on catecholamine-induced cardiomyopathy are limited to several case reports,with few reports of studies on children. [ncbi.nlm.nih.gov]

Perioperative mortality of children with paraganglioma is high, but preoperative therapy and anesthetic management of paraganglioma resection are controversial in children [ncbi.nlm.nih.gov]

Disorder of Catecholamine Synthesis

(catecholamine-secreting tumors). [labtestsonline.org]

Pheochromocytoma is a neuroendocrine tumor of the medulla of the adrenal glands originating in the chromaffin cells, which secretes excessive amounts of catecholamines, usually [newworldencyclopedia.org]

Tests used for determining the presence of catecholamine-secreting tumors (pheochromocytomas and paragangliomas) include plasma catecholamines, urine catecholamines, plasma [labtestsonline.org]

Acute Myocardial Infarction

Paragangliomas, extra-adrenal pheochromocytomas, are rare catecholamine-secreting tumor. [ncbi.nlm.nih.gov]

Intestinal Pseudo-Obstruction

A rare cause of intestinal pseudo-obstruction Paraganglioma’s are rare, catecholamine-secreting tumours. [poj.peeters-leuven.be]

Acrodysostosis Type 1

Glomus Tumors, Familial Nonchromaffin Paragangliomas Pheochromocytomas (PCC) and paragangliomas (PGL) are rare catecholamine-secreting tumors that arise from the chromaffin [centogene.com]

Secreting paraganglioma is a tumor derived from extra-adrenal chromaffin cells of the sympathetic paravertebral ganglia of thorax, abdomen, and pelvis. [centogene.com]

Pheochromocytoma is a tumor arising from adrenomedullary chromaffin cells that commonly produce one or more catecholamine neurotransmitters: adrenalin, noradrenaline, and [centogene.com]

Ganglioneuroma

As such, paragangliomas in the HN area usually do not secret catecholamines. [medicine.uiowa.edu]

Amar et al., Changes in urinary total metanephrine excretion in recurrent and malignant pheochromocytomas and secreting paragangliomas. [charite.de]

As such, tumors arising from the paravertebral paraganglia are essentially "extra-adrenal pheochromocytoma" and frequently secret excess catecholamine. [medicine.uiowa.edu]

Activity of Mitochondrial Complex II Decreased

A SHD1 R589W mutation has been reported in a case of catecholamine-secreting abdominal paraganglioma, leading to lowered SDH activity and a pseudohypoxia response ( 23 ). [pnas.org]

Dilated Cardiomyopathy

[…] or secreting paraganglioma. [ncbi.nlm.nih.gov]

Cases already described are mainly related to high blood pressure, and rarely to an "acute catecholamine cardiomyopathy" more frequently found in adults with pheochromocytoma [ncbi.nlm.nih.gov]

Multiple Endocrine Neoplasia Type 2A

[…] of New Mexico Rehman Anis A Southern Illinois University BOOK Paragangliomas are rare, catecholamine (norepinephrine) secreting neuroendocrine tumors commonly located in [unboundmedicine.com]

GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE/176(1-2)/pp.16-21, 2017-01 Loss of SDHB Elevates Catecholamine Synthesis and Secretion Depending on ROS Production [trios.tsukuba.ac.jp]

Head-and-neck paragangliomas in the jugular foramen, ear, or carotid body are less differentiated tumors. [unboundmedicine.com]

Paralytic Ileus

Except for the paragangliomas that originate from the organ of Zuckerkandl and produce various catecholamines, functional paragangliomas in various body sites secrete only [jmedicalcasereports.biomedcentral.com]

Most paragangliomas with catecholamine hypersecretion are localized to the abdomen and pelvis [2]. [jmedicalcasereports.biomedcentral.com]

secretion [2]. [jmedicalcasereports.biomedcentral.com]

Gastric Leiomyosarcoma

The paragangliomas (diagnosed between age 12 to 48 years) are generally catecholamine secreting, they are present in multiple sites in 22% and may undergo malignant change [familialcancerdatabase.nl]

Hemothorax

Case Report Introduction Mediastinal paraganglioma is a rare neurogenic tumor that originates from paraganglia, which can either be functional when catecholamine is secreted [jtd.amegroups.com]

Most nonfunctional mediastinal paraganglioma are usually found incidentally. [jtd.amegroups.com]

18-Hydroxylase Deficiency

Additional Information Catecholamine-producing tumors may arise in the adrenal medulla (pheochromocytomas) or in extraadrenal chromaffin cells (secreting paragangliomas). [medicbind.com]

[…] high amounts of catecholamines, usually noradrenaline (norepinephrine) and adrenaline (epinephrine). [medicbind.com]

[…] neuroendocrine tumor of the medulla of the adrenal glands (originating in the chromaffin cells), or extra-adrenal chromaffin tissue that failed to involute after birth and secretes [medicbind.com]

Secondary Parkinsonism

Pheochromocytoma, paraganglioma, or other catecholamine secretive neoplasm. 18. Known hypersensitivity to the ingredients of IMPs used. 19. [clinicaltrialsregister.eu]

Psychosis

types of neural crest cell tumors that secrete catecholamines. [ncbi.nlm.nih.gov]

[…] examining the possible relationship of neural crest cell tumors to schizophrenia, the author found several case reports of psychosis resulting from pheochromocytomas and paragangliomas [ncbi.nlm.nih.gov]