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59 Possible Causes for Caused by Mutation in the Anoctamin 10 Gene, Neuronal Loss and Gliosis in the Inferior Olives

  • Adult-Onset Autosomal Recessive Cerebellar Ataxia

    Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] Neuropathological examination reveals loss of normal pigmentation in the substantia nigra, OPCA (atrophy of the cerebellum, basis pontis, and inferior olives), and atrophy[neuropathology-web.org]

  • Olivopontocerebellar Atrophy

    There is neuronal loss and gliosis in the inferior olives, pons, cerebellum, substantia nigra, locus ceruleus, striatum and the intermediolateral column of the spinal cord[dizziness-and-balance.com] Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] Neuropathological examination reveals loss of normal pigmentation in the substantia nigra, OPCA (atrophy of the cerebellum, basis pontis, and inferior olives), and atrophy[neuropathology-web.org]

    Missing: Caused by Mutation in the Anoctamin 10 Gene
  • Striatonigral Degeneration

    There is neuronal loss and gliosis in the inferior olives, pons, cerebellum, substantia nigra, locus ceruleus, striatum and the intermediolateral column of the spinal cord[dizziness-and-balance.com] Inferior olives and dentate nucleus were well outlined.[dokumen.tips] Microscopic examination revealed rarefied structure of both putamina, marked loss of large and small neurons, fibrillar gliosis, and proliferation of capillaries (Fig. 1 A[dokumen.tips]

    Missing: Caused by Mutation in the Anoctamin 10 Gene
  • Shy Drager Syndrome

    loss, gliosis, and microvacuolation in the involved neuronal systems.[emedicine.medscape.com] Patients with MSA-C primarily have shrinkage of the cerebellum, middle cerebellar peduncles, inferior olives, and basis pontis. [14] Histopathologic findings include neuronal[emedicine.medscape.com]

    Missing: Caused by Mutation in the Anoctamin 10 Gene
  • Left Ventricular Noncompaction

    LGMD2L is caused by a mutation on chromosome 11 in the ANO5 gene.[emedicine.medscape.com] ANO5 encodes a member of the Anoctamin family, comprised of at least 10 proteins all with 8 transmembrane domains.[emedicine.medscape.com]

    Missing: Neuronal Loss and Gliosis in the Inferior Olives
  • Limb-Girdle Muscular Dystrophy Type 2L

    […] by mutations in the Dysferlin ( DYSF ) gene. 10–12 The human Anoctamins (ANO) compose a family of at least ten proteins all exhibiting eight transmembrane domains and a DUF590[ncbi.nlm.nih.gov] LGMD2L is caused by a mutation on chromosome 11 in the ANO5 gene.[emedicine.medscape.com] […] characterized by initial distal limb weakness. 9 In the cases of dysferlinopathies, both a proximal LGMD2B phenotype and a distal Miyoshi myopathy phenotype (MM [MIM 254130 ]) are caused[ncbi.nlm.nih.gov]

    Missing: Neuronal Loss and Gliosis in the Inferior Olives
  • Ataxia

    Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] In addition, mild secondary neuronal cell loss with gliosis was noted in the dentate nucleus and inferior olive.[doi.org] Neuropathological examination reveals loss of normal pigmentation in the substantia nigra, OPCA (atrophy of the cerebellum, basis pontis, and inferior olives), and atrophy[neuropathology-web.org]

    Missing: Caused by Mutation in the Anoctamin 10 Gene
  • Limb-Girdle Muscular Dystrophy Type 1G

    LGMD2L is caused by a mutation on chromosome 11 in the ANO5 gene.[emedicine.medscape.com] ANO5 encodes a member of the Anoctamin family, comprised of at least 10 proteins all with 8 transmembrane domains.[emedicine.medscape.com]

    Missing: Neuronal Loss and Gliosis in the Inferior Olives
  • Muscular Dystrophy-Dystroglycanopathy Type C4

    LGMD2L is caused by a mutation on chromosome 11 in the ANO5 gene.[emedicine.medscape.com] ANO5 encodes a member of the Anoctamin family, comprised of at least 10 proteins all with 8 transmembrane domains.[emedicine.medscape.com]

    Missing: Neuronal Loss and Gliosis in the Inferior Olives
  • Sarcotubular Myopathy

    LGMD2L is caused by a mutation on chromosome 11 in the ANO5 gene.[emedicine.medscape.com] ANO5 encodes a member of the Anoctamin family, comprised of at least 10 proteins all with 8 transmembrane domains.[emedicine.medscape.com]

    Missing: Neuronal Loss and Gliosis in the Inferior Olives

Further symptoms