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35 Possible Causes for Caused by Mutation in the Laminin Gamma-2 Gene, Syndactyly Does Not Occur

  • Herlitz Disease

    Mutations in genes coding for laminin-332 subunits (alpha-3 chain, laminin beta-3 chain, laminin gamma-2 chain), collagen XVII ( BP180 ), a6 integrin, and b4 integrin have[emedicine.medscape.com] More than half of junctional epidermolysis bullosa cases are caused by one of two recurrent nonsense mutations in the LAMB3 gene, which is helpful for mutation analysis and[emedicine.medscape.com] These diseases all cause blistering in the lamina lucida and variable hemidesmosomal abnormalities.[emedicine.medscape.com]

  • Foot Deformity

    Syndactyly: Syndactyly is the presence of fused digits and may occur along with other congenital anomalies or as an isolated problem.[orthopedicsports.com] It rarely causes any problems and does not need any treatment.[orthopedicsports.com]

    Missing: Caused by Mutation in the Laminin Gamma-2 Gene
  • Hammer Toe

    Syndactyly: Syndactyly is the presence of fused digits and may occur along with other congenital anomalies or as an isolated problem.[oamortho.com] It rarely causes any problems and does not need any treatment.[oamortho.com]

    Missing: Caused by Mutation in the Laminin Gamma-2 Gene
  • Crossed Polysyndactyly

    On the other hand, synPolydactyly is classified as a form of syndactyly because Polydactyly does not occur in the absence of syndactyly (McKusick).[rrnursingschool.biz] This association has been classified as a form of Polydactyly because syndactyly does not occur in the absence of Polydactyly in these families (Temtamy and McKusick 1978;[rrnursingschool.biz] Polysyndactyly (preaxial Polydactyly IV, OMIM 174700) is a familial disorder involving a combination of preaxial Polydactyly and syndactyly of digits 3 and 4 (Fig. 6.24 a,[rrnursingschool.biz]

    Missing: Caused by Mutation in the Laminin Gamma-2 Gene
  • Junctional Epidermolysis Bullosa

    Each gene encodes one of the three chains of heterotrimer laminin-332 proteins (including the alpha-3 chain, beta-3 chain and gamma-2-chain) responsible for the adherence[ncbi.nlm.nih.gov] Mutations in genes coding for laminin-332 subunits (alpha-3 chain, laminin beta-3 chain, laminin gamma-2 chain), collagen XVII ( BP180 ), a6 integrin, and b4 integrin have[emedicine.medscape.com] The Herlitz junctional epidermolysis bullosa (H-JEB) subtype usually presents as a severe lethal inherited variant of epidermolysis bullosa (EB) caused by a homozygous mutation[ncbi.nlm.nih.gov]

    Missing: Syndactyly Does Not Occur
  • Epidermolysis Bullosa

    Mutations in genes coding for laminin-332 subunits (alpha-3 chain, laminin beta-3 chain, laminin gamma-2 chain), collagen XVII ( BP180 ), a6 integrin, and b4 integrin have[emedicine.medscape.com] More than half of junctional epidermolysis bullosa cases are caused by one of two recurrent nonsense mutations in the LAMB3 gene, which is helpful for mutation analysis and[emedicine.medscape.com] These diseases all cause blistering in the lamina lucida and variable hemidesmosomal abnormalities.[emedicine.medscape.com]

    Missing: Syndactyly Does Not Occur
  • Syndactyly

    This condition does not have a notable cause and may occur in isolation or is inherited.[epainassist.com] This Occur?[sickkids.ca] In some fetuses, this process does not occur completely between all fingers or toes and some residual webbing remains.[en.wikipedia.org]

    Missing: Caused by Mutation in the Laminin Gamma-2 Gene
  • Epidermolysis Bullosa Simplex

    Mutations in genes coding for laminin-332 subunits (alpha-3 chain, laminin beta-3 chain, laminin gamma-2 chain), collagen XVII ( BP180 ), a6 integrin, and b4 integrin have[emedicine.com] More than half of junctional epidermolysis bullosa cases are caused by one of two recurrent nonsense mutations in the LAMB3 gene, which is helpful for mutation analysis and[emedicine.com] These diseases all cause blistering in the lamina lucida and variable hemidesmosomal abnormalities.[emedicine.com]

    Missing: Syndactyly Does Not Occur
  • Dystrophic Epidermolysis Bullosa

    Mutations in genes coding for laminin-332 subunits (alpha-3 chain, laminin beta-3 chain, laminin gamma-2 chain), collagen XVII ( BP180 ), a6 integrin, and b4 integrin have[emedicine.medscape.com] More than half of junctional epidermolysis bullosa cases are caused by one of two recurrent nonsense mutations in the LAMB3 gene, which is helpful for mutation analysis and[emedicine.medscape.com] These diseases all cause blistering in the lamina lucida and variable hemidesmosomal abnormalities.[emedicine.medscape.com]

    Missing: Syndactyly Does Not Occur
  • Polydactyly

    Syndactyly and polydactyly are about equally common disorders. Combinations of both can occur as well - webbed extra fingers. Why does a child have this?[eatonhand.com] Sometimes the fingers don't split apart enough, and webbed fingers result: syndactyly . Sometimes a extra split forms and extra fingers result: polydactyly.[eatonhand.com]

    Missing: Caused by Mutation in the Laminin Gamma-2 Gene

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