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27 Possible Causes for CD27+ B Cells Decreased

  • Periodontitis

    Among these CD27 B cells, the proportion of the switched memory subset was significantly higher.[ncbi.nlm.nih.gov] At the same time, human B1 cells, which were previously associated with a regulatory function (CD20 CD69-CD43 CD27 CD11b ), decreased in SP patients.[ncbi.nlm.nih.gov] The RANKL expression increased in every B cell subset from the SP patients and was significantly greater in activated B cells than in the subjects without periodontitis.[ncbi.nlm.nih.gov]

  • Pregnancy

    Most CVID patients show a general decrease in the expression of CD27 in B cells.[ncbi.nlm.nih.gov] However, an assessment of the subpopulations of T and B cells and the outcome of pregnancy in women with CVID has not been reported till date.[ncbi.nlm.nih.gov]

  • PGM3-Related Congenital Disorder of Glycosylation

    Title Other Names: Phosphoglucomutase 3 deficiency; CID due to PGM3 deficiency; PGM3-related congenital disorder of glycosylation; Phosphoglucomutase 3 deficiency; CID due to PGM3 deficiency; PGM3-related congenital disorder of glycosylation; Combined immunodeficiency due to PGM3 deficiency; Immunodeficiency 23;[…][rarediseases.info.nih.gov]

  • Chronic Alcoholism

    The distribution of PB B-cell subsets (immature/regulatory, naïve, CD27(-) and CD27( ) memory B lymphocytes, and circulating plasmablasts of distinct immunoglobulin-Ig-isotypes[ncbi.nlm.nih.gov] RESULTS: Patients with AH showed significantly decreased numbers of total PB B lymphocytes (vs. controls and AWLD), at the expense of immature, memory, and, to a lesser extent[ncbi.nlm.nih.gov]

  • Autoimmune Thrombocytopenia

    Decreased frequencies of memory B cells in splenectomized individuals were observed, with a rapid decline of CD27 IgD and a slower decrease of CD27 IgD- and CD27-/IgD- cells[ncbi.nlm.nih.gov] cell activation.[ncbi.nlm.nih.gov] CD95 B cells were substantially increased in all subsets in patients with active AITP, indicating their enhanced activation status.[ncbi.nlm.nih.gov]

  • B-Cell Chronic Lymphocytic Leukemia

    […] of CD25 /CD127 cells.[stm.sciencemag.org] At day 169, CAR cells remained reasonably consistent with their day 56 counterparts, with the exception of a reduction in CD27 expression and a decrease in the percentage[stm.sciencemag.org] Fig. 4 Prolonged surface CAR19 expression and establishment of functional memory CART19 cells in vivo. ( A and B ) T cell immunophenotyping of CD4 (A) and CD8 (B) T cell subsets[stm.sciencemag.org]

  • Henoch-Schönlein Purpura

    The percentage of B10 cells and CD19 CD24 hi CD38 hi B cells was reduced in HSPN patients and that of CD19 CD24 hi CD27 B cells was decreased only in HSPN patients with hematuria[ncbi.nlm.nih.gov]

  • Recurrent Respiratory Papillomatosis

    Flow cytometry analysis of B-cell compartment showed that the frequency of both CD19 CD27 hi plasma cells and CD19 CD27 memory B cells were decreased in JORRP patients.[ncbi.nlm.nih.gov]

  • Idiopathic Neutropenia

    […] memory IgD - /CD27 B-cells was decreased in the patients.[ncbi.nlm.nih.gov] The proportion of CD19 cells did not differ between patients and controls; however the proportion of the naïve IgD /CD27 - B-cells was increased and the proportion of class-switched[ncbi.nlm.nih.gov]

  • Systemic Lupus Erythematosus

    There is decreased suppression of memory B cells with increased CD27 /IgD- which is related to increased disease activity and renal lupus [ 6, 7, 8 ].[pubs.sciepub.com] Polyclonal B-cell activation occurs in SLE and a shift towards immature B cells.[pubs.sciepub.com]

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