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820 Possible Causes for CD27+ B Cells Decreased, Desbuquois Dysplasia, Thiamine Decreased

  • Chronic Alcoholism

    The distribution of PB B-cell subsets (immature/regulatory, naïve, CD27(-) and CD27( ) memory B lymphocytes, and circulating plasmablasts of distinct immunoglobulin-Ig-isotypes[ncbi.nlm.nih.gov] This means the number of thiamine transporters to bring thiamine into the enterocyte was decreased.[ebmconsult.com] […] of the liver, decreased intestinal absorption, impaired conversion of thiamine to its active form (thiamine pyrophosphate), and increased demand to metabolise the carbohydrates[bestpractice.bmj.com]

    Missing: Desbuquois Dysplasia
  • Immunodeficiency Type 23

    […] resembling Desbuquois dysplasia.[scilit.net] Two of the three children had skeletal anomalies resembling Desbuquois dysplasia: short stature, brachydactyly, dysmorphic facial features, and intellectual disability.[f1000.com] Keywords: Bone marrow failure / Congenital Disorder of Glycosylation / Pgm3 / Severe combined immunodeficiency / whole‐exome sequencing / DESBUQUOIS‐LIKE DYSPLASIA Click here[scilit.net]

    Missing: Thiamine Decreased
  • Alcohol Abuse

    NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. Office of the Surgeon General (US); National Institute on Alcohol Abuse and Alcoholism (US); Substance Abuse and Mental Health Services Administration (US). The Surgeon General's Call to Action To Prevent and Reduce[…][ncbi.nlm.nih.gov]

    Missing: CD27+ B Cells Decreased Desbuquois Dysplasia
  • Metaphyseal Chondrodysplasia, Spahr Type

    Desbuquois Dysplasia ; 48. gPAPP Dysplasia ; 49. Pseudodiastrophic Dysplasia ; 50.[amazon.de] That, a modern study in humans showed increases and decreases in CBF depending on the cerebral region [122].[sarcomacancer.org] Desbuquois Dysplasia 48. gPAPP Dysplasia 49. Pseudodiastrophic Dysplasia 50.[amazon.it]

    Missing: CD27+ B Cells Decreased
  • Graves Disease

    Thyroid hemiagenesis is a rare congenital dysplasia, whereas a variety of pathological changes may occur in residual thyroid lobe. The most frequently described pathology in residual thyroid lobe is Graves' hyperthyroidism. Although I therapy has been generally recommended as the preferred treatment for Graves'[…][ncbi.nlm.nih.gov]

    Missing: CD27+ B Cells Decreased Desbuquois Dysplasia
  • Wernicke Encephalopathy

    As the mechanism of Wernicke encephalopathy, we thought that decreased ability to store thiamine due to liver cirrhosis led to depletion of thiamine faster than had been expected[ncbi.nlm.nih.gov] Thiamine deficiency decreased cerebral glucose metabolism and mitochondrial dysfunction depleted ATP and increased free radicals injury of neuronal elements (e.g., myelin[amboss.com] Other manifestations of thiamine deficiency involve the cardiovascular system (wet beriberi) and peripheral nervous system (nutritional polyneuropathy).[emedicine.medscape.com]

    Missing: CD27+ B Cells Decreased Desbuquois Dysplasia
  • Pregnancy

    Most CVID patients show a general decrease in the expression of CD27 in B cells.[ncbi.nlm.nih.gov] Moreover, thiamine pyrophosphate, an intermediate product of glycolysis/gluconeogenesis, significantly increased in the second trimester, and argininosuccinic acid and oxalosuccinic[ncbi.nlm.nih.gov] However, an assessment of the subpopulations of T and B cells and the outcome of pregnancy in women with CVID has not been reported till date.[ncbi.nlm.nih.gov]

    Missing: Desbuquois Dysplasia
  • Leigh's Disease

    Abstract A series of children with Leigh's disease had normal hepatic pyruvate carboxylase activity, increased cerebral thiamine diphosphate, and decreased cerebral thiamine[ncbi.nlm.nih.gov] […] and, subsequently, decreased thiamine uptake by components of the respiratory complex of the mitochondria.[dovepress.com] In their study, Gerards et al found a homozygous nonsense mutation in the thiamine transporter gene SLC19A3 (c.20 C A). 20 This mutation resulted in a premature stop codon[dovepress.com]

    Missing: CD27+ B Cells Decreased Desbuquois Dysplasia
  • Fetal Malnutrition

    Health Econ. 2017 Oct;26(10):1264-1277. doi: 10.1002/hec.3397. Epub 2016 Aug 19. Author information 1 School of Economics, Singapore Management University, Singapore. 2 Department of Economics, Ohio State University, Columbus, OH, USA. Abstract We report evidence of long-term adverse health impacts of fetal malnutrition[…][ncbi.nlm.nih.gov]

    Missing: CD27+ B Cells Decreased Desbuquois Dysplasia
  • Thiamine Deficiency

    Thiamine treatment decreased the serum concentrations of lactate and pyruvate in patient 2, but not patient 1.[ncbi.nlm.nih.gov] Alcohol especially decreases the amount of thiamine diphosphate.[oapublishinglondon.com] Decreased uptake of thiamine from the GI tract: Active transport of thiamine into enterocytes is disturbed during acute alcohol exposure.[en.wikipedia.org]

    Missing: CD27+ B Cells Decreased Desbuquois Dysplasia

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