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227 Possible Causes for CD4 Lymphocytes Decreased, Increased Susceptibility to Infections

  • Primary Immune Deficiency Disorder

    The most common symptom of PIDD is an increased susceptibility to infection.[symptoma.com] The percentage of CD4 T cells is low (about 25% of lymphocytes) and the CD4/C8 ratio is 0.5.[emedicine.medscape.com] Abstract: Patients with primary immunodeficiency diseases most often are recognized because of their increased susceptibility to infection (chronic or recurrent infections[asmscience.org]

  • Cartilage Hair Hypoplasia

    CONCLUSIONS: Humoral immunity is impaired in CHH and contributes to the increased susceptibility to infections.[ncbi.nlm.nih.gov] Of the patients, 57% had a decreased CD4 cell count which led to a decreased total count of T-lymphocytes in 52% and a subnormal CD4 /CD8 cell ratio in 32%.[ncbi.nlm.nih.gov] Defective cellular immunity had been observed in 88% and increased susceptibility to infections in 56% of the patients. Six patients had died of primary infections.[ncbi.nlm.nih.gov]

  • Wiskott Aldrich Syndrome

    Wiskott-Aldrich syndrome (WAS) is an X-linked recessive disorder characterized by thrombocytopenia, small platelets, eczema, increased susceptibility to infection, and immunodeficiency[ncbi.nlm.nih.gov] However, with respect to the major symptoms of WAS, none of these three patients showed either thrombocytopenia or increased susceptibility to infection, but one patient showed[ncbi.nlm.nih.gov] These immune problems vary in severity and include an increased susceptibility to infection from bacteria, viruses, and fungi.[ghr.nlm.nih.gov]

  • Acquired Immunodeficiency Syndrome

    […] microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms.[hon.ch] No side effects such as decreases in white blood cell counts or CD4 lymphocyte levels were seen during S-1 therapy.[ncbi.nlm.nih.gov] , and increased susceptibility to opportunistic infections and malignant neoplasms [ 1 ].[link.springer.com]

  • Congenital Acquired Immune Deficiency Syndrome

    KEY TERMS Agammaglobulinemia —The lack of gamma globulins in the blood, associated with an increased susceptibility to infection.[healthofchildren.com] As the infection progresses, it interferes more with the immune system, increasing the susceptibility to common infections like tuberculosis, as well as other opportunistic[icd.codes] Persistent bacterial infections - sinusitis, otitis and bronchitis. Increased susceptibility to opportunistic infections (OIs) and recurrent fungal yeast infections.[slideshare.net]

  • Acute Bronchitis

    Symptoms include labored breathing, the inability to forcefully blow air out of the lungs, and an increased susceptibility to respiratory tract infections.[encyclopedia.com] […] the CD4/CD8 ratio, activation of CD8 lymphocytes, and exudation as indicated by an increase in fluid phase fibrinogen.[ncbi.nlm.nih.gov] Sputum findings identified intense airway inflammation characterised by increased total cell and lymphocyte counts followed by an increase in neutrophils and a decrease in[ncbi.nlm.nih.gov]

  • Bronchitis

    Try to avoid being around smokers because even secondhand smoke can make you more susceptible to viral infections and increase congestion in your airway.[kidshealth.org] Peripheral blood CD4 T lymphocytes in the observation group patients expressed lower levels of nicotinic acetylcholine receptors α7 (α7nAChR) compared to the control group[ncbi.nlm.nih.gov] Symptoms include labored breathing, the inability to forcefully blow air out of the lungs, and an increased susceptibility to respiratory tract infections.[medical-dictionary.thefreedictionary.com]

  • Anemia

    Symptoms you may experience: Fatigue, weakness, irritability, pale skin, headaches, brittle nails, decreased appetite, increased susceptibility to infections, and a decreased[gluten.org] T-lymphocyte counts and Hb levels. 7,16 The causes of anemia in HIV/AIDS may include inflammatory cytokine production and suppression of hematopoiesis, decreased erythropoietin[ajmc.com] It also increases susceptibility to infection, and the likelihood of experiencing weakness or fatigue symptoms.[povertyactionlab.org]

  • Shwachman Syndrome

    Affected individuals with neutropenia may also have additional abnormalities believed to result from an increased susceptibility to infections.[rarediseases.org] Seven out of nine patients studied had at least one T-cell abnormality comprising a low percentage of total circulating T lymphocytes or CD3 /CD4 cell subpopulations or decreased[thedoctorsdoctor.com] These may include increased tooth decay (dental caries), mouth ulcers, and/or disease of the tissues that surround and support the teeth (periodontal disease).[rarediseases.org]

  • Adenovirus Infection

    Increasingly potent immunosuppressive agents have reduced the incidence of rejection of transplanted organs while increasing patient susceptibility to opportunistic infections[ncbi.nlm.nih.gov] An increase of lymphocyte numbers was clearly associated with a decrease of the plasma DNA load.[nature.com] Both TSA and MG-132 pretreatments could increase the CAR expression in the two cell lines, but the drug pretreatments could only make A549 cells more susceptible to adenovirus[ncbi.nlm.nih.gov]

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