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138 Possible Causes for cell transformation viral

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  • Hematopoietic Stem Cell Transplantation

    After decades since the discovery of natural killer (NK) cells as potential effector cells fighting malignantly transformed and virally infected cells, little progress has[]

  • Solanum

    Virally transformed normal human prostate epithelial PZ-HPV-7 cells and their cancer counterpart CA-HPV-10 cells, were used to evaluate the growth-inhibitory effects of the[] […] cancer cells without affecting normal prostate epithelial cells.[] Here we demonstrate that a polyphenolic extract derived from ripe berries of Solanum nigrum (SN) differentially causes cell cycle arrest and apoptosis in various human prostate[]

  • Influenza Virus Vaccine

    The viral propagation was determined on avian origin primary cell cultures, transformed mammalian cell lines, and in ECE.[] Transformed cell lines have attained regulatory approvals for vaccine production.[] Based on the fact that the avian influenza virus would infect the cells derived from its natural host, the viral growth characteristics were studied on chicken embryo-derived[]

  • Hairy Leukoplakia

    In latent transforming Epstein-Barr virus (EBV) infection, viral proteins that induce cell growth are expressed.[] In contrast to other permissive herpesvirus infections, expression of EBV transforming proteins within the permissively infected HLP tissue enables epithelial cell survival[] […] and may enhance viral replication.[]

  • Merkel Cell Carcinoma

    MCCs frequently contain Merkel cell polyomavirus (MCPyV) DNA and express viral transforming antigens, sT and tLT, but the role of these putative oncogenes in MCC development[] Merkel cell carcinoma (MCC) tumor cells express several markers detected in normal Merkel cells, a nonproliferative population of neuroendocrine cells that arise from epidermis[] , and this tumor's cell of origin, are unknown.[]

  • T-Cell Prolymphocytic Leukemia

    During latent infection, EBV continuously expresses a number of viral genes which are essential for cell transformation and maintenance of the malignant phenotype of EBV-related[]

  • Xeroderma Pigmentosum Variant

    […] production was not contributing to the increased transformation seen for these cells.[] XP variant cells were also found to produce lower than normal quantities of virus following infection with either damages or undamaged virus, suggesting that increased viral[]

  • Marginal Zone Lymphoma

    […] and other surface receptors, and (ii) direct transformation by intracellular viral proteins, the former being probably predominant in MZL.[] The role of HCV in lymphomagenesis is not yet fully understood but several mechanisms have been proposed including (i) chronic external stimulation through the B-cell receptor[]

  • Posttransplant Lymphoproliferative Disease

    (EBV) replication and transformation of B cells.[] Posttransplant lymphoproliferative disease (PTLD) after lung transplantation occurs due to immunosuppressant therapy which limits antiviral host immunity and permits Epstein-Barr viral[]

  • Adenovirus

    Human adenovirus (HAdV) E1B-55K is a multifunctional regulator of productive viral replication and oncogenic transformation in nonpermissive mammalian cells.[] Both early viral proteins recruit specific host factors to form an E3 ubiquitin ligase complex that targets antiviral host substrates for proteasomal degradation.[]

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