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120 Possible Causes for Central Focal Spikes, 'Eye of the Tiger' Sign on MRI, Jerk-Locked Premyoclonus Spikes

  • Benign Adult Familial Myoclonic Epilepsy

    T2 weighted brain MRI shows an ”eye of the tigersign corresponding to pallidal hypointensity with a high signal center.[neuroweb.us] , multifocal, or bilateral distribution and time locked to sharp-wave or spike-wave discharges on the contralateral central areas. 34, 35 ENM has a wide etiological spectrum[clinicalgate.com] […] cortical spikes detected by the jerk-locked back-averaging) ( Ikeda et al., 1990 ).[academic.oup.com]

  • Generalized Clonic or Tonic-Clonic Seizures

    premyoclonus spikes Hand tremor Neuronal loss in central nervous system Cutaneous photosensitivity Hyperreflexia Heterogeneous Weight loss Dystonia Splenomegaly Thrombocytopenia[mendelian.co] […] callosum Muscular hypotonia Infantile onset Intellectual disability, moderate Intention tremor Progressive neurologic deterioration Absence seizures Nevus EEG abnormality Jerk-locked[mendelian.co]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Epilepsy

    In infancy, the EEG background was normal (1), showed diffuse (3) or focal slowing that was temporal (1) and in the left hemisphere (1), and showed focal (central, temporal[brain.oxfordjournals.org] ) discharges or generalized spike wave and polyspike wave activity.[brain.oxfordjournals.org] After infancy, the EEG background was normal (5), showed diffuse slowing (10) or focal slowing that was bilateral fronto-temporal (2) and left temporal (1).[brain.oxfordjournals.org]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • Juvenile Myoclonic Epilepsy

    History Juvenile myoclonic epilepsy (JME) is diagnosed on the basis of clinical findings. Video-electroencephalography (EEG) monitoring of typical seizures is the criterion standard, but in the great majority of patients, a working diagnosis of probable JME is made on the basis of the clinical history, often with[…][emedicine.medscape.com]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • West Syndrome

    IARS2 encodes isoleucine-tRNA synthetase, which is aclass-1 amino acyl-tRNA synthetase. IARS2 mutations are reported to cause Leigh syndrome or cataracts, growth hormone deficiency, sensory neuropathy, sensorineural hearing loss, and skeletal dysphasia syndrome (CAGSSS). To our knowledge, IARS2 mutations and[…][ncbi.nlm.nih.gov]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • Idiopathic Generalized Epilepsy

    Epilepsia. 2012 Dec;53(12):2079-90. doi: 10.1111/j.1528-1167.2012.03723.x. Epub 2012 Oct 25. Author information 1 Department of Medicine, St. Vincent's Hospital, The University of Melbourne, Victoria Parade, Fitzroy, Victoria, Australia. udaya.seneviratne@svhm.org.au Abstract Prognosis describes the trajectory and long-term[…][ncbi.nlm.nih.gov]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • Organic Brain Syndrome

    Abstract This study addresses the prevalence of organic brain syndrome (OBS) among long-term toluene-exposed rotagravure workers who are still working. The prevalence of OBS in 22 workers exposed to toluene for a minimum of 12 years and 19 unexposed control subjects, matched for age and employment status,[…][ncbi.nlm.nih.gov]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • Encephalopathy

    Posterior reversible encephalopathy syndrome is an encephalopathy that can be clinically characterized by headache, altered mental status and/or seizures. Neuroimaging demonstrates usually reversible bilateral subcortical vasogenic occipital-parietal edema. Exact pathophysiology remains unclear but is commonly[…][ncbi.nlm.nih.gov]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • Juvenile Absence Epilepsy

    We describe a 68-year-old woman who had typical absence seizures since 14 years of age. The absences were refractory to treatment and persisted into adulthood, with no seizure-free periods until seizure control at 59 years of age. After six years of being seizure-free, she presented with an episode[…][ncbi.nlm.nih.gov]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes
  • Uremic Encephalopathy

    BACKGROUND AND PURPOSE: Uremic encephalopathy is a metabolic disorder in patients with renal failure. The purpose of this study was to describe the MR imaging findings of uremic encephalopathy. MATERIALS AND METHODS: This study retrospectively reviewed MR imaging findings in 10 patients with clinically proved uremic[…][ncbi.nlm.nih.gov]

    Missing: 'Eye of the Tiger' Sign on MRI Jerk-Locked Premyoclonus Spikes

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